Antineoplaston treatment for advanced hepatocellular carcinoma.

  • Authors:
    • T Kumabe
    • H Tsuda
    • M Uchida
    • Y Ogoh
    • N Hayabuchi
    • M Sata
    • O Nakashima
    • H Hara
  • View Affiliations

  • Published online on: November 1, 1998     https://doi.org/10.3892/or.5.6.1363
  • Pages: 1363-1370
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Abstract

Antineoplaston A10 injection (antineoplaston A10 I) exhibited cystostatic growth inhibition of human hepatocellular carcinoma (HCC) cells in vitro and showed minimum adverse effects in a phase I clinical trial. Advanced HCC is hard to control because the potent anticancer drugs or embolizations easily induce hepatic failure. We review herein 2 cases of advanced HCC treated with antineoplaston A10 I. Both cases showed interesting responses to antineoplaston A10 I. One showed massive coagulation necrosis of tumors after intra-arterial infusion of antineoplaston A10 I and the other showed resolution of portal vein tumor thrombosis with systemic infusion of antineoplaston A10 I. The usefulness of anti-neoplaston A10 I in terminal staged HCC is discussed.

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November 1998
Volume 5 Issue 6

Print ISSN: 1021-335X
Online ISSN:1791-2431

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APA
Kumabe, T., Tsuda, H., Uchida, M., Ogoh, Y., Hayabuchi, N., Sata, M. ... Hara, H. (1998). Antineoplaston treatment for advanced hepatocellular carcinoma.. Oncology Reports, 5, 1363-1370. https://doi.org/10.3892/or.5.6.1363
MLA
Kumabe, T., Tsuda, H., Uchida, M., Ogoh, Y., Hayabuchi, N., Sata, M., Nakashima, O., Hara, H."Antineoplaston treatment for advanced hepatocellular carcinoma.". Oncology Reports 5.6 (1998): 1363-1370.
Chicago
Kumabe, T., Tsuda, H., Uchida, M., Ogoh, Y., Hayabuchi, N., Sata, M., Nakashima, O., Hara, H."Antineoplaston treatment for advanced hepatocellular carcinoma.". Oncology Reports 5, no. 6 (1998): 1363-1370. https://doi.org/10.3892/or.5.6.1363