|
1
|
Pardini B, Kumar R, Naccarati A, Prasad
RB, Forsti A, Polakova V, Vodickova L, Novotny J, Hemminki K and
Vodicka P: MTHFR and MTRR genotype and haplotype analysis and
colorectal cancer susceptibility in a case-control study from the
Czech Republic. Mutat Res. 721:74–80. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Cao HX, Gao CM, Takezaki T, Wu JZ, Ding
JH, Liu YT, Li SP, Su P, Cao J, Hamajima N and Tajima K: Genetic
polymorphisms of methylenetetrahydrofolate reductase and
susceptibility to colorectal cancer. Asian Pac J Cancer Prev.
9:203–208. 2008.PubMed/NCBI
|
|
3
|
Jemal A, Bray F, Center MM, Ferlay J, Ward
E and Forman D: Global cancer statistics. CA Cancer J Clin.
61:69–90. 2011. View Article : Google Scholar
|
|
4
|
Blount BC, Mack MM, Wehr CM, MacGregor JT,
Hiatt RA, Wang G, Wickramasinghe SN, Everson RB and Ames BN: Folate
deficiency causes uracil misincorporation into human DNA and
chromosome breakage: implications for cancer and neuronal damage.
Proc Natl Acad Sci USA. 94:3290–3295. 1997. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Choi SW and Mason JB: Folate and
carcinogenesis: an integrated scheme. J Nutr. 130:129–132.
2000.PubMed/NCBI
|
|
6
|
Cui LH, Shin MH, Kweon SS, Kim HN, Song
HR, Piao JM, Choi JS, Shim HJ, Hwang JE, Kim HR, et al:
Methylenetetrahydrofolate reductase C677T polymorphism in patients
with gastric and colorectal cancer in a Korean population. BMC
Cancer. 10:2362010. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Goyette P, Sumner JS, Milos R, Duncan AM,
Rosenblatt DS, Matthews RG and Rozen R: Human
methylenetetrahydrofolate reductase: isolation of cDNA, mapping and
mutation identification. Nat Genet. 7:195–200. 1994. View Article : Google Scholar
|
|
8
|
Pereira AC, Schettert IT, Morandini Filho
AA, Guerra-Shinohara EM and Krieger JE: Methylenetetrahydrofolate
reductase (MTHFR) c677t gene variant modulates the homocysteine
folate correlation in a mild folate-deficient population. Clin Chim
Acta. 340:99–105. 2004. View Article : Google Scholar
|
|
9
|
Ogino S and Wilson RB: Genotype and
haplotype distributions of MTHFR677C>T and 1298A>C single
nucleotide polymorphisms: a meta-analysis. J Hum Genet. 48:1–7.
2003.PubMed/NCBI
|
|
10
|
Chen J, Giovannucci E, Kelsey K, et al: A
methylenetetrahydrofolate reductase polymorphism and the risk of
colorectal cancer. Cancer Res. 56:4862–4864. 1996.PubMed/NCBI
|
|
11
|
van der Put NM, Gabreels F, Stevens EM,
Smeitink JA, Trijbels FJ, Eskes TK, van den Heuvel LP and Blom HJ:
A second common mutation in the methylenetetrahydrofolate reductase
gene: an additional risk factor for neural-tube defects? Am J Hum
Genet. 62:1044–1051. 1998.PubMed/NCBI
|
|
12
|
Keku T, Millikan R, Worley K, Winkel S,
Eaton A, Biscocho L, Martin C and Sandler R:
5,10-Methylenetetrahydrofolate reductase codon 677 and 1298
polymorphisms and colon cancer in African Americans and whites.
Cancer Epidemiol Biomarkers Prev. 11:1611–1621. 2002.PubMed/NCBI
|
|
13
|
Heijmans BT, Boer JM, Suchiman HE,
Cornelisse CJ, Westendorp RG, Kromhout D, Feskens EJ and Slagboom
PE: A common variant of the methylenetetrahydrofolate reductase
gene (1p36) is associated with an increased risk of cancer. Cancer
Res. 63:1249–1253. 2003.PubMed/NCBI
|
|
14
|
Shannon B, Gnanasampanthan S, Beilby J and
Iacopetta B: A polymorphism in the methylenetetrahydrofolate
reductase gene predisposes to colorectal cancers with
microsatellite instability. Gut. 50:520–524. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Yin G, Kono S, Toyomura K, Hagiwara T,
Nagano J, Mizoue T, Mibu R, Tanaka M, Kakeji Y, Maehara Y, et al:
Methylenetetrahydrofolate reductase C677T and A1298C polymorphisms
and colorectal cancer: the Fukuoka Colorectal Cancer Study. Cancer
Sci. 95:908–913. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Ma J, Stampfer MJ, Giovannucci E, et al:
Methylenetetrahydrofolate reductase polymorphism, dietary
interactions, and risk of colorectal cancer. Cancer Res.
57:1098–1102. 1997.PubMed/NCBI
|
|
17
|
Ryan BM, Molloy AM, McManus R, Arfin Q,
Kelleher D, Scott JM and Weir DG: The methylenetetrahydrofolate
reductase (MTHFR) gene in colorectal cancer: role in tumor
development and significance of allelic loss in tumor progression.
Int J Gastrointest Cancer. 30:105–111. 2001. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Sachse C, Smith G, Wilkie MJ, Barrett JH,
Waxman R, Sullivan F, Forman D, Bishop DT and Wolf CR; Colorectal
Cancer Study Group. A pharmacogenetic study to investigate the role
of dietary carcinogens in the etiology of colorectal cancer.
Carcinogenesis. 23:1839–1849. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Pufulete M, Al-Ghnaniem R, Leather AJ,
Appleby P, Gout S, Terry C, Emery PW and Sanders TA: Folate status,
genomic DNA hypomethylation, and risk of colorectal adenoma and
cancer: a case control study. Gastroenterology. 124:1240–1248.
2003. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Plaschke J, Schwanebeck U, Pistorius S,
Saeger HD and Schackert HK: Methylenetetrahydrofolate reductase
polymorphisms and risk of sporadic and hereditary colorectal cancer
with or without microsatellite instability. Cancer Lett.
191:179–185. 2003. View Article : Google Scholar
|
|
21
|
Toffoli G, Gafà R, Russo A, Lanza G,
Dolcetti R, Sartor F, Libra M, Viel A and Boiocchi M:
Methylenetetrahydrofolate reductase 677 C → T polymorphism and risk
of proximal colon cancer in north Italy. Clin Cancer Res.
9:743–748. 2003.
|
|
22
|
Ulvik A, Vollset SE, Hansen S, Gislefoss
R, Jellum E and Ueland PM: Colorectal cancer and the
methylenetetrahydrofolate reductase 677C → T and methionine
synthase 2756A → G polymorphisms: a study of 2,168 case-control
pairs from the JANUS cohort. Cancer Epidemiol Biomarkers Prev.
13:2175–2180. 2004.
|
|
23
|
Landi S, Gemignani F, Moreno V,
Gioia-Patricola L, Chabrier A, Guino E, Navarro M, de Oca J,
Capellà G and Canzian F; Bellvitge Colorectal Cancer Study Group. A
comprehensive analysis of phase I and phase II metabolism gene
polymorphisms and risk of colorectal cancer. Pharmacogenet
Genomics. 15:535–546. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Koushik A, Kraft P, Fuchs CS, Hankinson
SE, Willett WC, Giovannucci EL and Hunter DJ: Nonsynonymous
polymorphisms in genes in the one-carbon metabolism pathway and
associations with colorectal cancer. Cancer Epidemiol Biomarkers
Prev. 15:2408–2017. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Van Guelpen B, Hultdin J, Johansson I,
Hallmans G, Stenling R, Riboli E, Winkvist A and Palmqvist R: Low
folate levels may protect against colorectal cancer. Gut.
55:1461–1466. 2006.PubMed/NCBI
|
|
26
|
Battistelli S, Vittoria A, Stefanoni M,
Bing C and Roviello F: Total plasma homocysteine and
methylenetetrahydrofolate reductase C677T polymorphism in patients
with colorectal carcinoma. World J Gastroenterol. 12:6128–6132.
2006.PubMed/NCBI
|
|
27
|
Osian G, Procopciuc L and Vlad L: MTHFR
polymorphisms as prognostic factors in sporadic colorectal cancer.
J Gastrointestin Liver Dis. 16:251–256. 2007.PubMed/NCBI
|
|
28
|
Lima CS, Nascimento H, Bonadia LC, Teori
MT, Coy CS, Goes JR, Costa FF and Bertuzzo CS: Polymorphisms in
methylenetetrahydrofolate reductase gene (MTHFR) and the age of
onset of sporadic colorectal adenocarcinoma. Int J Colorectal Dis.
22:757–763. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Theodoratou E, Farrington SM, Tenesa A,
McNeill G, Cetnarskyj R, Barnetson RA, Porteous ME, Dunlop MG and
Campbell H: Dietary vitamin B6 intake and the risk of colorectal
cancer. Cancer Epidemiol Biomarkers Prev. 17:171–182. 2008.
View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Sharp L, Little J, Brockton NT, Cotton SC,
Masson LF, Haites NE and Cassidy J: Polymorphisms in the
methylenetetrahydrofolate reductase (MTHFR) gene, intakes of folate
and related B vitamins and colorectal cancer: a case-control study
in a population with relatively low folate intake. Br J Nutr.
99:379–389. 2008. View Article : Google Scholar
|
|
31
|
Eklöf V, Van Guelpen B, Hultdin J,
Johansson I, Hallmans G and Palmqvist R: The reduced folate carrier
(RFC1) 80G > A and folate hydrolase 1 (FOLH1) 1561C > T
polymorphisms and the risk of colorectal cancer: a nested
case-referent study. Scand J Clin Lab Invest. 68:393–401. 2008.
|
|
32
|
Küry S, Buecher B, Robiou-du-Pont S, Scoul
C, Colman H, Le Neel T, Le Houérou C, Faroux R, Ollivry J, Lafraise
B, Chupin LD, Sébille V and Bézieau S: Low-penetrance alleles
predisposing to sporadic colorectal cancers: a French
case-controlled genetic association study. BMC Cancer.
8:3262008.PubMed/NCBI
|
|
33
|
Derwinger K, Wettergren Y, Odin E,
Carlsson G and Gustavsson B: A study of the MTHFR gene polymorphism
C677T in colorectal cancer. Clin Colorectal Cancer. 8:43–48. 2009.
View Article : Google Scholar : PubMed/NCBI
|
|
34
|
de Vogel S, Wouters KA, Gottschalk RW, van
Schooten FJ, de Goeij AF, de Bruïne AP, Goldbohm RA, van den Brandt
PA, Weijenberg MP and van Engeland M: Genetic variants of methyl
metabolizing enzymes and epigenetic regulators: associations with
promoter CpG island hypermethylation in colorectal cancer. Cancer
Epidemiol Biomarkers Prev. 18:3086–3096. 2009.PubMed/NCBI
|
|
35
|
Fernández-Peralta AM, Daimiel L, Nejda N,
Iglesias D, Medina Arana V and González-Aguilera JJ: Association of
polymorphisms MTHFR C677T and A1298C with risk of colorectal
cancer, genetic and epigenetic characteristic of tumors, and
response to chemotherapy. Int J Colorectal Dis. 25:141–151.
2010.PubMed/NCBI
|
|
36
|
Gallegos-Arreola MP, Garcia-Ortiz JE,
Figuera LE, Puebla-Perez AM, Morgan-Villela G and Zuniga-Gonzalez
GM: Association of the 677C → T polymorphism in the MTHFR gene with
colorectal cancer in Mexican patients. Cancer Genomics Proteomics.
6:183–188. 2009.
|
|
37
|
Komlosi V, Hitre E, Pap E, Adleff V, Reti
A, Szekely E, Biro A, Rudnai P, Schoket B, Muller J, et al: SHMT1
1420 and MTHFR 677 variants are associated with rectal but not
colon cancer. BMC Cancer. 10:5252010. View Article : Google Scholar : PubMed/NCBI
|
|
38
|
Karpinski P, Myszka A, Ramsey D, Misiak B,
Gil J, Laczmanska I, Grzebieniak Z, Sebzda T, Smigiel R, Stembalska
A and Sasiadek MM: Polymorphisms in methyl-group metabolism genes
and risk of sporadic colorectal cancer with relation to the CpG
island methylator phenotype. Cancer Epidemiol. 34:338–344. 2010.
View Article : Google Scholar : PubMed/NCBI
|
|
39
|
Vossen CY, Hoffmeister M, Chang-Claude JC,
Rosendaal FR and Brenner H: Clotting factor gene polymorphisms and
colorectal cancer risk. J Clin Oncol. 29:1722–1727. 2011.
View Article : Google Scholar : PubMed/NCBI
|
|
40
|
Eussen SJ, Vollset SE, Igland J, Meyer K,
Fredriksen A, et al: Plasma folate, related genetic variants, and
colorectal cancer risk in EPIC. Cancer Epidemiol Biomarkers Prev.
19:1328–1340. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
41
|
Lee JE, Wei EK, Fuchs CS, Hunter DJ, Lee
IM, Selhub J, et al: Plasma folate, methylenetetrahydrofolate
reductase (MTHFR), and colorectal cancer risk in three large nested
case-control studies. Cancer Causes Control. 23:537–545. 2012.
View Article : Google Scholar
|
|
42
|
Park KS, Mok JW and Kim JC: The 677C >
T mutation in 5,10-methylenetetrahydrofolate reductase and
colorectal cancer risk. Genet Test. 3:233–236. 1999.
|
|
43
|
Matsuo K, Hamajima N, Hirai T, Kato T,
Inoue M, Takezaki T and Tajima K: Methionine synthase reductase
gene A66G polymorphism is associated with risk of colorectal
cancer. Asian Pac J Cancer Prev. 3:353–359. 2002.PubMed/NCBI
|
|
44
|
Huang P, Zhou ZY, Ma HT, Liu JY, Zhou YH,
Cao J, Ge HY, Yu PW and Takezaki T: MTHFR polymorphisms and
colorectal cancer susceptibility in Chongqing people. Acta
Academiae Medicinae Militaris Tertiae. 25:1710–1713. 2003.(In
Chinese).
|
|
45
|
Kim DH, Ahn YO, Lee BH, Tsuji E, Kiyohara
C and Kono S: Methylenetetrahydrofolate reductase polymorphism,
alcohol intake, and risks of colon and rectal cancers in Korea.
Cancer Lett. 216:199–205. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
46
|
Matsuo K, Ito H, Wakai K, Hirose K, Saito
T, Suzuki T, Kato T, Hirai T, Kanemitsu Y, Hamajima H and Tajima K:
One-carbon metabolism related gene polymorphisms interact with
alcohol drinking to influence the risk of colorectal cancer in
Japan. Carcinogenesis. 26:2164–2171. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
47
|
Jiang Q, Chen K, Ma X, Li Q, Yu W, Shu G
and Yao K: Diets, polymorphisms of methylenetetrahydrofolate
reductase, and the susceptibility of colon cancer and rectal
cancer. Cancer Detect Prev. 29:146–154. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
48
|
Miao XP, Yang S, Tan W, Zhang XM, et al:
Association between genetic variations in methylenetetrahydrofolate
reductase and risk of colorectal cancer in a Chinese population.
Chin J Prev Med. 39:409–411. 2005.(In Chinese).
|
|
49
|
Otani T, Iwasaki M, Hanaoka T, Kobayashi
M, Ishihara J, Natsukawa S, Shaura K, Koizumi Y, Kasuga Y,
Yoshimura K, Yoshida T and Tsugane S: Folate, vitamin B6, vitamin
B12, and vitamin B2 intake, genetic polymorphisms of related
enzymes, and risk of colorectal cancer in a hospital-based
case-control study in Japan. Nutr Cancer. 53:42–50. 2005.
View Article : Google Scholar
|
|
50
|
Wang J, Gajalakshmi V, Jiang J, Kuriki K,
Suzuki S, Nagaya T, Nakamura S, Akasaka S, Ishikawa H and Tokudome
S: Associations between 5,10-methylenetetrahydrofolate reductase
codon 677 and 1298 genetic polymorphisms and environmental factors
with reference to susceptibility to colorectal cancer: a
case-control study in an Indian population. Int J Cancer.
118:991–997. 2006. View Article : Google Scholar
|
|
51
|
Chang SC, Lin PC, Lin JK, Yang SH, Wang HS
and Li AF: Role of MTHFR polymorphisms and folate levels in
different phenotypes of sporadic colorectal cancers. Int J
Colorectal Dis. 22:483–489. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
52
|
Zeybek U, Yaylim I, Yilmaz H, Agaçhan B,
Ergen A, Arikan S, Bayrak S and Isbir T: Methylenetetrahydrofolate
reductase C677T polymorphism in patients with gastric and
colorectal cancer. Cell Biochem Funct. 25:419–422. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
53
|
Jin XX, Zhu ZZ, Wang AZ and Jia HR:
Association of methylenetetrahydrofolate reductase C677T
polymorphism with genetic susceptibility to colorectal cancer.
World Chin J Digestol. 15:2754–2757. 2007.(In Chinese).
|
|
54
|
Mokarram P, Naghibalhossaini F, Saberi
Firoozi M, Hosseini SV, Izadpanah A, Salahi H, Malek-Hosseini SA,
Talei A and Mojallal M: Methylenetetrahydrofolate reductase C677T
genotype affects promoter methylation of tumor-specific genes in
sporadic colorectal cancer through an interaction with
folate/vitamin B12 status. World J Gastroenterol. 14:3662–3671.
2008. View Article : Google Scholar
|
|
55
|
Haghighi MM, Radpour R, Mahmoudi T,
Mohebbi SR, Vahedi M and Zali MR: Association between MTHFR
polymorphism (C677T) with nonfamilial colorectal cancer. Oncol Res.
18:57–63. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
56
|
Zhang YL, Yuan XY, Zhang Z, Yang H, Zhou
YH, Pan YM, Zhou ZY, Liang HJ and Cao J: Relationship of genetic
polymorphisms in methylenetetrahydrofolate reductase and alcohol
drinking with the risk of colorectal cancer. Chin J Cancer Prev
Treat. 15:1298–1301. 2008.(In Chinese).
|
|
57
|
Promthet SS, Pientong C, Ekalaksananan T,
Wiangnon S, Poomphakwaen K, Songserm N, Chopjitt P, Moore MA and
Tokudome S: Risk factors for colon cancer in Northeastern Thailand:
interaction of MTHFR codon 677 and 1298 genotypes with
environmental factors. J Epidemiol. 20:329–338. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
58
|
Naghibalhossaini F, Mokarram P, Khalili I,
Vasei M, Hosseini SV, Ashktorab H, Rasti M and Abdollahi K: MTHFR
C677T and A1298C variant genotypes and the risk of microsatellite
instability among Iranian colorectal cancer patients. Cancer Genet
Cytogenet. 197:142–151. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
59
|
Kim JW, Park HM, Choi YK, Chong SY, Oh D
and Kim NK: Polymorphisms in genes involved in folate metabolism
and plasma DNA methylation in colorectal cancer patients. Oncol
Rep. 25:167–172. 2011.PubMed/NCBI
|
|
60
|
Chandy S, Sadananda Adiga MN, Ramachandra
N, Krishnamoorthy S, Ramaswamy G, Savithri HS and Krishnamoorthy L:
Association of methylenetetrahydrofolate reductase gene
polymorphisms and colorectal cancer in India. Indian J Med Res.
131:659–664. 2010.PubMed/NCBI
|
|
61
|
Zhu F, Wang YM and QY Z: A case-control
study of plasma homocysteine, serum folate, the polymorphism of
methylenetetrahydrofolate reductase in colorectal cancer. J
Southeast Univ Med Sci Edi. 29:88–92. 2010.
|
|
62
|
Kang BS, Ahn DH, Kim NK and Kim JW:
Relationship between metabolic syndrome and MTHFR polymorphism in
colorectal cancer. J Korean Soc Coloproctol. 27:78–82. 2011.
View Article : Google Scholar : PubMed/NCBI
|
|
63
|
Prasad VV and Wilkhoo H: Association of
the functional polymorphism C677T in the methylenetetrahydrofolate
reductase gene with colorectal, thyroid, breast, ovarian, and
cervical cancers. Onkologie. 34:422–426. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
64
|
Sameer AS, Shah ZA, Nissar S, Mudassar S
and Siddiqi MA: Risk of colorectal cancer associated with the
methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism in
the Kashmiri population. Genet Mol Res. 10:1200–1210. 2011.
View Article : Google Scholar : PubMed/NCBI
|
|
65
|
Li H, Xu WL, Shen HL, Chen QY, Hui LL,
Long LL and Zhu XL: Methylenetetrahydrofolate reductase genotypes
and haplotypes associated with susceptibility to colorectal cancer
in an eastern Chinese Han population. Genet Mol Res. 10:3738–3746.
2011. View Article : Google Scholar : PubMed/NCBI
|
|
66
|
Yin G, Ming H, Zheng X, Xuan Y, Liang J
and Jin X: Methylenetetrahydrofolate reductase C677T gene
polymorphism and colorectal cancer risk: A case-control study.
Oncol Lett. 4:365–369. 2012.PubMed/NCBI
|
|
67
|
Kim J, Cho YA, Kim DH, Lee BH, Hwang DY,
Jeong J, Lee HJ, Matsuo K, Tajima K and Ahn YO: Dietary intake of
folate and alcohol, MTHFR C677T polymorphism, and colorectal cancer
risk in Korea. Am J Clin Nutr. 95:405–412. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
68
|
El Awady MK, Karim AM, Hanna LS, El
Husseiny LA, El Sahar M, Menem HA and Meguid NA:
Methylenetetrahydrofolate reductase gene polymorphisms and the risk
of colorectal carcinoma in a sample of Egyptian individuals. Cancer
Biomark. 5:233–240. 2009.PubMed/NCBI
|
|
69
|
Guimarães JL, de Ayrizono ML, Coy CS and
Lima CS: Gene polymorphisms involved in folate and methionine
metabolism and increased risk of sporadic colorectal
adenocarcinoma. Tumour Biol. 32:853–861. 2011.PubMed/NCBI
|
|
70
|
Slattery ML, Potter JD, Samowitz W,
Schaffer D and Leppert M: Methylenetetrahydrofolate reductase,
diet, and risk of colon cancer. Cancer Epidemiol Biomarkers Prev.
8:513–518. 1999.PubMed/NCBI
|
|
71
|
Curtin K, Bigler J, Slattery ML, Caan B,
Potter JD and Ulrich CM: MTHFR C677T and A1298C polymorphisms:
diet, estrogen, and risk of colon cancer. Cancer Epidemiol
Biomarkers Prev. 13:285–292. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
72
|
Murtaugh MA, Curtin K, Sweeney C, Wolff
RK, Holubkov R, Caan BJ and Slattery ML: Dietary intake of folate
and co-factors in folate metabolism, MTHFR polymorphisms, and
reduced rectal cancer. Cancer Causes Control. 18:153–163. 2007.
View Article : Google Scholar : PubMed/NCBI
|
|
73
|
Iacopetta B, Heyworth J, Girschik J, Grieu
F, Clayforth C and Fritschi L: The MTHFR C677T and DeltaDNMT3B
C-149T polymorphisms confer different risks for right- and
left-sided colorectal cancer. Int J Cancer. 125:84–90. 2009.
View Article : Google Scholar : PubMed/NCBI
|
|
74
|
Reeves SG, Meldrum C, Groombridge C,
Spigelman AD, Suchy J, Kurzawski G, Lubinski J, McElduff P and
Scott RJ: MTHFR 677 C>T and 1298 A>C polymorphisms and the
age of onset of colorectal cancer in hereditary nonpolyposis
colorectal cancer. Eur J Hum Genet. 17:629–635. 2009.
|
|
75
|
Yang XX, Li FX, Yi J, Li X, Sun JZ and Hu
NY: An association of methylenetetrahydrofolate reductase reductase
C677T and gastric cancer, colorectal cancer and lung cancer
susceptibility. Guangdong Med J. 31:2375–2377. 2010.(In
Chinese).
|
|
76
|
Zhu Q, Jin Z, Yuan Y, Lu Q, Ge D and Zong
M: Impact of MTHFR gene C677T polymorphism on Bcl-2 gene
methylation and protein expression in colorectal cancer. Scand J
Gastroenterol. 46:436–445. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
77
|
Le Marchand L, Wilkens LR, Kolonel LN and
Henderson BE: The MTHFR C677T polymorphism and colorectal cancer:
the multiethnic cohort study. Cancer Epidemiol Biomarkers Prev.
14:1198–1203. 2005.PubMed/NCBI
|