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Review

Cell death, dysglycemia and myocardial infarction (Review)

  • Authors:
    • Xiao‑Fang Tian
    • Ming‑Xia Cui
    • Shi‑Wei Yang
    • Yu‑Jie Zhou
    • Da‑Yi Hu
  • View Affiliations / Copyright

    Affiliations: Key Laboratory of Preclinical Study for New Drugs of Gansu Province, Department of Pharmacology, School of Basic Medical Sciences, Lanzhou University, Lanzhou, Gansu 730000, P.R. China, 12th Ward, Department of Cardiology, Beijing An Zhen Hospital, Capital Medical University, Beijing Institute of Heart Lung and Blood Vessel Disease, The Key Laboratory of Remodeling-Related Cardiovascular Disease, Ministry of Education, Beijing 100029, P.R. China, Department of Cardiology, People's Hospital Affiliated to Peking University, Beijing 100044, P.R. China
  • Pages: 341-346
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    Published online on: February 25, 2013
       https://doi.org/10.3892/br.2013.67
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Abstract

Dysglycemia (hyper- and hypoglycemia) has been associated with higher mortality among patients suffering from myocardial infarction (MI). Moreover, dysglycemia may induce cell death. Cell death (necrosis, apoptosis and autophagy) is a ubiquitous process that characterizes the course of several diseases, including MI, and occurs in diverse forms varying in mechanism, pattern and consequence. Therefore, cell death is a potential pathway through which dysglycemia affects the outcome of MI and it is essential to regulate myocardial cell death in the treatment of patients with MI caused by dysglycemia. In this review, we summarized the mechanisms of MI at the cellular level and the regulatory effects of dysglycemia on myocardial cell death. The ability to modulate myocardial cell death may be a promising target of new treatments aimed at limiting MI caused by dysglycemia. However, further research is required to elucidate the mechanisms underlying cell death regulation in MI caused by dysglycemia.
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Copy and paste a formatted citation
Spandidos Publications style
Tian XF, Cui MX, Yang SW, Zhou YJ and Hu DY: Cell death, dysglycemia and myocardial infarction (Review). Biomed Rep 1: 341-346, 2013.
APA
Tian, X., Cui, M., Yang, S., Zhou, Y., & Hu, D. (2013). Cell death, dysglycemia and myocardial infarction (Review). Biomedical Reports, 1, 341-346. https://doi.org/10.3892/br.2013.67
MLA
Tian, X., Cui, M., Yang, S., Zhou, Y., Hu, D."Cell death, dysglycemia and myocardial infarction (Review)". Biomedical Reports 1.3 (2013): 341-346.
Chicago
Tian, X., Cui, M., Yang, S., Zhou, Y., Hu, D."Cell death, dysglycemia and myocardial infarction (Review)". Biomedical Reports 1, no. 3 (2013): 341-346. https://doi.org/10.3892/br.2013.67
Copy and paste a formatted citation
x
Spandidos Publications style
Tian XF, Cui MX, Yang SW, Zhou YJ and Hu DY: Cell death, dysglycemia and myocardial infarction (Review). Biomed Rep 1: 341-346, 2013.
APA
Tian, X., Cui, M., Yang, S., Zhou, Y., & Hu, D. (2013). Cell death, dysglycemia and myocardial infarction (Review). Biomedical Reports, 1, 341-346. https://doi.org/10.3892/br.2013.67
MLA
Tian, X., Cui, M., Yang, S., Zhou, Y., Hu, D."Cell death, dysglycemia and myocardial infarction (Review)". Biomedical Reports 1.3 (2013): 341-346.
Chicago
Tian, X., Cui, M., Yang, S., Zhou, Y., Hu, D."Cell death, dysglycemia and myocardial infarction (Review)". Biomedical Reports 1, no. 3 (2013): 341-346. https://doi.org/10.3892/br.2013.67
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