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Review

Betatrophin provides a new insight into diabetes treatment and lipid metabolism (Review)

  • Authors:
    • Jin‑Zhou Zhu
    • Chao‑Hui Yu
    • You‑Ming Li
  • View Affiliations / Copyright

    Affiliations: Department of Gastroenterology and Hepatology, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, Zhejiang 310003, P.R. China
  • Pages: 447-451
    |
    Published online on: May 20, 2014
       https://doi.org/10.3892/br.2014.284
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Abstract

Replenishing the insulin?producing ??cell mass is considered to be a potential cure for diabetes. A recent study identified a secreted protein, known as betatrophin, which potently induces pancreatic ??cell proliferation. Notably, a number of studies reportedly identified betatrophin, which is also known as lipasin, atypical angiopoietin?like 8 and refeeding?induced fat and liver protein, and considered to be a novel regulator in lipid metabolism according to the studies. The identification of betatrophin was considered to create novel opportunities for potential diabetes therapy. In the present study, the current knowledge of betatrophin is reviewed, with regards to its character and function in lipid homeostasis and pancreatic ??cell proliferation.
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Copy and paste a formatted citation
Spandidos Publications style
Zhu JZ, Yu CH and Li YM: Betatrophin provides a new insight into diabetes treatment and lipid metabolism (Review). Biomed Rep 2: 447-451, 2014.
APA
Zhu, J., Yu, C., & Li, Y. (2014). Betatrophin provides a new insight into diabetes treatment and lipid metabolism (Review). Biomedical Reports, 2, 447-451. https://doi.org/10.3892/br.2014.284
MLA
Zhu, J., Yu, C., Li, Y."Betatrophin provides a new insight into diabetes treatment and lipid metabolism (Review)". Biomedical Reports 2.4 (2014): 447-451.
Chicago
Zhu, J., Yu, C., Li, Y."Betatrophin provides a new insight into diabetes treatment and lipid metabolism (Review)". Biomedical Reports 2, no. 4 (2014): 447-451. https://doi.org/10.3892/br.2014.284
Copy and paste a formatted citation
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Spandidos Publications style
Zhu JZ, Yu CH and Li YM: Betatrophin provides a new insight into diabetes treatment and lipid metabolism (Review). Biomed Rep 2: 447-451, 2014.
APA
Zhu, J., Yu, C., & Li, Y. (2014). Betatrophin provides a new insight into diabetes treatment and lipid metabolism (Review). Biomedical Reports, 2, 447-451. https://doi.org/10.3892/br.2014.284
MLA
Zhu, J., Yu, C., Li, Y."Betatrophin provides a new insight into diabetes treatment and lipid metabolism (Review)". Biomedical Reports 2.4 (2014): 447-451.
Chicago
Zhu, J., Yu, C., Li, Y."Betatrophin provides a new insight into diabetes treatment and lipid metabolism (Review)". Biomedical Reports 2, no. 4 (2014): 447-451. https://doi.org/10.3892/br.2014.284
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