Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Oncology Letters
      • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Biomedical Reports
      • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • Information for Authors
    • Information for Reviewers
    • Information for Librarians
    • Information for Advertisers
    • Conferences
  • Language Editing
Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • For Authors
    • For Reviewers
    • For Librarians
    • For Advertisers
    • Conferences
  • Language Editing
Login Register Submit
  • This site uses cookies
  • You can change your cookie settings at any time by following the instructions in our Cookie Policy. To find out more, you may read our Privacy Policy.

    I agree
Search articles by DOI, keyword, author or affiliation
Search
Advanced Search
presentation
Biomedical Reports
Join Editorial Board Propose a Special Issue
Print ISSN: 2049-9434 Online ISSN: 2049-9442
Journal Cover
May-2015 Volume 3 Issue 3

Full Size Image

Sign up for eToc alerts
Recommend to Library

Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

Journal Cover
May-2015 Volume 3 Issue 3

Full Size Image

Sign up for eToc alerts
Recommend to Library

  • Article
  • Citations
    • Cite This Article
    • Download Citation
    • Create Citation Alert
    • Remove Citation Alert
    • Cited By
  • Similar Articles
    • Related Articles (in Spandidos Publications)
    • Similar Articles (Google Scholar)
    • Similar Articles (PubMed)
  • Download PDF
  • Download XML
  • View XML
Article

Topical application of a cleanser containing extracts of Diospyros kaki folium, Polygonum cuspidatum and Castanea crenata var. dulcis reduces skin oil content and pore size in human skin

  • Authors:
    • Bo Mi Lee
    • Sungkwan An
    • Soo‑Yeon Kim
    • Hyun Joo Han
    • Yu‑Jin Jeong
    • Kyoung‑Rok Lee
    • Nam Kyung Roh
    • Kyu Joong Ahn
    • In‑Sook An
    • Hwa Jun Cha
  • View Affiliations / Copyright

    Affiliations: Korea Institute for Skin and Clinical Sciences and Molecular-Targeted Drug Research Center, Konkuk University, Seoul 143‑701, Republic of Korea, AMI Cosmetics Co., Ltd., Seoul 121‑888, Republic of Korea, Department of Dermatology, Konkuk University School of Medicine, Seoul 143‑701, Republic of Korea
  • Pages: 343-346
    |
    Published online on: February 25, 2015
       https://doi.org/10.3892/br.2015.435
  • Expand metrics +
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Metrics: Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )
Cited By (CrossRef): 0 citations Loading Articles...

This article is mentioned in:



Abstract

The effects of skin pores on skin topographic features can be reduced by decreasing excessive production and accumulation of sebum and elimination of comedones. Therefore, a cosmetic cleanser that regulates sebum homeostasis is required. In the present study, the effects of a cosmetic cleanser that contained Diospyros kaki folium, Polygonum cuspidatum and Castanea crenata var. dulcis (DPC) was examined on the removal of sebum and on skin pore size. Healthy volunteers (n=23) aged 20‑50 years were asked to apply the test materials to the face. Skin oil content, pore size, pore number and extracted sebum surface area were measured using various measurement methods. All the measurements were performed at pre‑ and post‑application of the test materials. When the cosmetic cleanser containing DPC was applied to the skin, the oil content decreased by 77.3%, from 6.19 to 1.40. The number of skin pores decreased by 24.83%, from 125.39 to 94.23. Skin pore size decreased from 0.07 to 0.02 µm3 (71.43% decrease). The amount of extracted sebum increased by 335% when the DPC cleanser was used. Compared to the control cleanser, skin oil content was significantly decreased when the cleanser that contained DPC was used. The cleanser containing DPC also decreased pore size and number. Finally, the DPC cleanser easily removed solidified sebum from the skin.
View Figures

Figure 1

Figure 2

Figure 3

Figure 4

View References

1 

Zouboulis CC, Baron JM, Böhm M, Kippenberger S, Kurzen H, Reichrath J and Thielitz A: Frontiers in sebaceous gland biology and pathology. Exp Dermatol. 17:542–551. 2008. View Article : Google Scholar : PubMed/NCBI

2 

Picardo M, Ottaviani M, Camera E and Mastrofrancesco A: Sebaceous gland lipids. Dermatoendocrinol. 1:68–71. 2009. View Article : Google Scholar : PubMed/NCBI

3 

Cheng Y, Dong Y, Wang J, et al: Moisturizing and anti-sebum secretion effects of cosmetic application on human facial skin. J Cosmet Sci. 60:7–14. 2009.PubMed/NCBI

4 

Uhoda E, Piérard-Franchimont C, Petit L and Piérard GE: The conundrum of skin pores in dermocosmetology. Dermatology. 210:3–7. 2005. View Article : Google Scholar : PubMed/NCBI

5 

Roh M, Han M, Kim D and Chung K: Sebum output as a factor contributing to the size of facial pores. Br J Dermatol. 155:890–894. 2006. View Article : Google Scholar : PubMed/NCBI

6 

Roh M, Goo B, Jung J, Chung H and Chung K: Treatment of enlarged pores with the quasi long-pulsed versus Q-switched 1064 nm Nd:YAG lasers: A split-face, comparative, controlled study. Laser Ther. 20:175–180. 2011. View Article : Google Scholar : PubMed/NCBI

7 

Cunliffe WJ, Holland DB and Jeremy A: Comedone formation: Etiology, clinical presentation, and treatment. Clin Dermatol. 22:367–374. 2004. View Article : Google Scholar : PubMed/NCBI

8 

Chen G, Wei SH, Huang J and Sun J: A novel C-glycosylflavone from the leaves of Diospyros kaki. J Asian Nat Prod Res. 11:503–507. 2009. View Article : Google Scholar : PubMed/NCBI

9 

Yamada Y, Yamamoto A, Yoneda N and Nakatani N: Identification of kaempferol from the leaves of Diospyros kaki and its antimicrobial activity against streptococcus mutans. Biocontrol Sci. 4:97–100. 1999. View Article : Google Scholar

10 

Bei W, Zang L, Guo J, et al: Neuroprotective effects of a standardized flavonoid extract from Diospyros kaki leaves. J Ethnopharmacol. 126:134–142. 2009. View Article : Google Scholar : PubMed/NCBI

11 

Sakanaka S, Tachibana Y and Okada Y: Preparation and antioxidant properties of extracts of Japanese persimmon leaf tea (kakinoha cha). Food Chem. 89:569–575. 2005. View Article : Google Scholar

12 

Kirino A, Takasuka Y, Nishi A, Kawabe S, Yamashita H, Kimoto M, Ito H and Tsuji H: Analysis and functionality of major polyphenolic components of Polygonum cuspidatum (itadori). J Nutr Sci Vitaminol (Tokyo). 58:278–286. 2012. View Article : Google Scholar : PubMed/NCBI

13 

Leu YL, Hwang TL, Hu JW and Fang JY: Anthraquinones from Polygonum cuspidatum as tyrosinase inhibitors for dermal use. Phytother Res. 22:552–556. 2008. View Article : Google Scholar : PubMed/NCBI

14 

Zahedi HS, Jazayeri S, Ghiasvand R, Djalali M and Eshraghian MR: Effects of Polygonum cuspidatum containing resveratrol on inflammation in male professional basketball players. Int J Prev Med. 4 (Suppl 1):S1–S4. 2013.PubMed/NCBI

15 

Ghanim H, Sia CL, Abuaysheh S, Korzeniewski K, Patnaik P, Marumganti A, Chaudhuri A and Dandona P: An antiinflammatory and reactive oxygen species suppressive effects of an extract of Polygonum cuspidatum containing resveratrol. J Clin Endocrinol Metab. 95:E1–E8. 2010. View Article : Google Scholar : PubMed/NCBI

16 

Chi YS, Heo MY, Chung JH, Jo BK and Kim HP: Effects of the chestnut inner shell extract on the expression of adhesion molecules, fibronectin and vitronectin, of skin fibroblasts in culture. Arch Pharm Res. 25:469–474. 2002. View Article : Google Scholar : PubMed/NCBI

17 

Slotosch CM, Kampf G and Löffler H: Effects of disinfectants and detergents on skin irritation. Contact Dermat. 57:235–241. 2007. View Article : Google Scholar

18 

Nilius B, Prenen J and Owsianik G: Irritating channels: The case of TRPA1. J Physiol. 589:1543–1549. 2011. View Article : Google Scholar : PubMed/NCBI

19 

Mittal M, Siddiqui MR, Tran K, Reddy SP and Malik AB: Reactive oxygen species in inflammation and tissue injury. Antioxid Redox Signal. 20:1126–1167. 2014. View Article : Google Scholar : PubMed/NCBI

20 

Naha PC, Davoren M, Lyng FM and Byrne HJ: Reactive oxygen species (ROS) induced cytokine production and cytotoxicity of PAMAM dendrimers in J774A.1 cells. Toxicol Appl Pharmacol. 246:91–99. 2010. View Article : Google Scholar : PubMed/NCBI

21 

Bikowski JB and Del Rosso JQ: Demodex dermatitis: A retrospective analysis of clinical diagnosis and successful treatment with topical crotamiton. J Clin Aesthet Dermatol. 2:20–25. 2009.PubMed/NCBI

22 

Jarmuda S, O'Reilly N, Zaba R, Jakubowicz O, Szkaradkiewicz A and Kavanagh K: Potential role of Demodex mites and bacteria in the induction of rosacea. J Med Microbiol. 61:1504–1510. 2012. View Article : Google Scholar : PubMed/NCBI

Related Articles

  • Abstract
  • View
  • Download
  • Twitter
Copy and paste a formatted citation
Spandidos Publications style
Lee BM, An S, Kim SY, Han HJ, Jeong YJ, Lee KR, Roh NK, Ahn KJ, An IS, Cha HJ, Cha HJ, et al: Topical application of a cleanser containing extracts of Diospyros kaki folium, Polygonum cuspidatum and Castanea crenata var. dulcis reduces skin oil content and pore size in human skin. Biomed Rep 3: 343-346, 2015.
APA
Lee, B.M., An, S., Kim, S., Han, H.J., Jeong, Y., Lee, K. ... Cha, H.J. (2015). Topical application of a cleanser containing extracts of Diospyros kaki folium, Polygonum cuspidatum and Castanea crenata var. dulcis reduces skin oil content and pore size in human skin. Biomedical Reports, 3, 343-346. https://doi.org/10.3892/br.2015.435
MLA
Lee, B. M., An, S., Kim, S., Han, H. J., Jeong, Y., Lee, K., Roh, N. K., Ahn, K. J., An, I., Cha, H. J."Topical application of a cleanser containing extracts of Diospyros kaki folium, Polygonum cuspidatum and Castanea crenata var. dulcis reduces skin oil content and pore size in human skin". Biomedical Reports 3.3 (2015): 343-346.
Chicago
Lee, B. M., An, S., Kim, S., Han, H. J., Jeong, Y., Lee, K., Roh, N. K., Ahn, K. J., An, I., Cha, H. J."Topical application of a cleanser containing extracts of Diospyros kaki folium, Polygonum cuspidatum and Castanea crenata var. dulcis reduces skin oil content and pore size in human skin". Biomedical Reports 3, no. 3 (2015): 343-346. https://doi.org/10.3892/br.2015.435
Copy and paste a formatted citation
x
Spandidos Publications style
Lee BM, An S, Kim SY, Han HJ, Jeong YJ, Lee KR, Roh NK, Ahn KJ, An IS, Cha HJ, Cha HJ, et al: Topical application of a cleanser containing extracts of Diospyros kaki folium, Polygonum cuspidatum and Castanea crenata var. dulcis reduces skin oil content and pore size in human skin. Biomed Rep 3: 343-346, 2015.
APA
Lee, B.M., An, S., Kim, S., Han, H.J., Jeong, Y., Lee, K. ... Cha, H.J. (2015). Topical application of a cleanser containing extracts of Diospyros kaki folium, Polygonum cuspidatum and Castanea crenata var. dulcis reduces skin oil content and pore size in human skin. Biomedical Reports, 3, 343-346. https://doi.org/10.3892/br.2015.435
MLA
Lee, B. M., An, S., Kim, S., Han, H. J., Jeong, Y., Lee, K., Roh, N. K., Ahn, K. J., An, I., Cha, H. J."Topical application of a cleanser containing extracts of Diospyros kaki folium, Polygonum cuspidatum and Castanea crenata var. dulcis reduces skin oil content and pore size in human skin". Biomedical Reports 3.3 (2015): 343-346.
Chicago
Lee, B. M., An, S., Kim, S., Han, H. J., Jeong, Y., Lee, K., Roh, N. K., Ahn, K. J., An, I., Cha, H. J."Topical application of a cleanser containing extracts of Diospyros kaki folium, Polygonum cuspidatum and Castanea crenata var. dulcis reduces skin oil content and pore size in human skin". Biomedical Reports 3, no. 3 (2015): 343-346. https://doi.org/10.3892/br.2015.435
Follow us
  • Twitter
  • LinkedIn
  • Facebook
About
  • Spandidos Publications
  • Careers
  • Cookie Policy
  • Privacy Policy
How can we help?
  • Help
  • Live Chat
  • Contact
  • Email to our Support Team