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Article

Aortic wall proteomic analysis in spontaneously hypertensive rats with a blood pressure decrease induced by 6-week load-free swimming

  • Authors:
    • Hong Feng
    • Haiying Li
    • Derong Zhang
    • Yungang Zhao
    • Ning Jiang
    • Xiaoling Zhao
    • Yu Zhang
    • Junzhen Tan
    • Wen Fang
    • Yong Zhang
    • Wei Liu
  • View Affiliations / Copyright

    Affiliations: Tianjin Key Laboratory of Exercise Physiology and Sports Medicine, Tianjin University of Sport, Tianjin 300381, P.R. China, Institute of Health and Environmental Medicine, Tianjin 300050, P.R. China, Department of Health and Exercise Science, Tianjin University of Sport, Tianjin 300381, P.R. China, Department of Family Planning, The Second Affiliated Hospital of Tianjin Medical University, Tianjin 300211, P.R. China, School of Integrative Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 300193, P.R. China, Department of Graduate, Tianjin University of Sport, Tianjin 300381, P.R. China
  • Pages: 681-686
    |
    Published online on: July 10, 2015
       https://doi.org/10.3892/br.2015.488
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Abstract

Decreased arterial compliance is one of the earliest detectable manifestations of adverse structural and functional changes within the vessel wall in hypertension. The proteomic approach is a powerful technique to analyze a complex mixture of proteins in various settings. Physical activity level was negatively associated with blood pressure. Sixteen 4‑week‑old male spontaneously hypertensive rats (SHR) and 16 Wistar‑Kyoto (WKY) rats were randomly divided into four groups: i) SHR exercise group, ii) SHR rest group, iii) WKY exercise group and iv) WKY rest group. In the SHR and WKY exercise groups, rats were treated with a 6‑week load‑free swimming protocol (1 h/day, 5 days/week). The blood pressure of the rats was tested by the CODATM2 single non‑invasive blood pressure measurement appliance. After the 6‑week swimming protocol, the total aorta excluding abdominal aorta was extracted. The proteins were separated by two‑dimensional gel electrophoresis and identified via LC‑mass spectrometry (MS)/MS. After 6‑week load‑free swimming, blood pressure decreased in the SHRs. Compared with sedentary SHRs, 11 spots on the 2D‑gel showed a significant difference in exercised SHRs. Nine of these were chosen for further identification. There were 5 upregulated proteins (long‑chain specific acyl‑CoA dehydrogenase, heat shock protein β‑1, isocitrate dehydrogenase subunit α, actin, α cardiac muscle 1 preprotein and calmodulin isoform 2) and 4 downregulated proteins (adipocyte‑type fatty acid‑binding protein, tubulin β‑2C chain, 78 kDa glucose‑regulated protein precursor and mimecan). Proteomics is an effective method to identify the target proteins of exercise intervention for hypertension.
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1 

Cavalcante JL, Lima JA, Redheuil A and Al-Mallah MH: Aortic stiffness: Current understanding and future directions. J Am Coll Cardiol. 57:1511–1522. 2011. View Article : Google Scholar : PubMed/NCBI

2 

Aebersold R and Mann M: Mass spectrometry-based proteomics. Nature. 422:198–207. 2003. View Article : Google Scholar : PubMed/NCBI

3 

Bian YL, Qi YX, Yan ZQ, Long DK, Shen BR and Jiang ZL: A proteomic analysis of aorta from spontaneously hypertensive rat: RhoGDI alpha upregulation by angiotensin II via AT(1) receptor. Eur J Cell Biol. 87:101–110. 2008. View Article : Google Scholar : PubMed/NCBI

4 

Horta PP, de Carvalho JJ and Mandarim-de-Lacerda CA: Exercise training attenuates blood pressure elevation and adverse remodeling in the aorta of spontaneously hypertensive rats. Life Sci. 77:3336–3343. 2005. View Article : Google Scholar : PubMed/NCBI

5 

Kimura H, Kon N, Furukawa S, Mukaida M, Yamakura F, Matsumoto K, Sone H and Murakami-Murofushi K: Effect of endurance exercise training on oxidative stress in spontaneously hypertensive rats (SHR) after emergence of hypertension. Clin Exp Hypertens. 32:407–415. 2010. View Article : Google Scholar : PubMed/NCBI

6 

Bobillier Chaumont S, Maupoil V, Jacques Lahet J and Berthelot A: Effect of exercise training on metallothionein levels of hypertensive rats. Med Sci Sports Exerc. 33:724–728. 2001. View Article : Google Scholar : PubMed/NCBI

7 

Zhang J, Ren CX, Qi YF, Lou LX, Chen L, Zhang LK, Wang X and Tang C: Exercise training promotes expression of apelin and APJ of cardiovascular tissues in spontaneously hypertensive rats. Life Sci. 79:1153–1159. 2006. View Article : Google Scholar : PubMed/NCBI

8 

Bradford MM: A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem. 72:248–254. 1976. View Article : Google Scholar : PubMed/NCBI

9 

Jenö P, Mini T, Moes S, Hintermann E and Horst M: Internal sequences from proteins digested in polyacrylamide gels. Anal Biochem. 224:75–82. 1995. View Article : Google Scholar : PubMed/NCBI

10 

Song YJ, Sawamura M, Ikeda K, et al: Training in swimming reduces blood pressure and increase muscle transportactivity as well as GLUT 4 contents in stroke-prone spontaneously hypertensive rats. Appl Human Sci. 17:275–280. 1998. View Article : Google Scholar : PubMed/NCBI

11 

Vogt M, Ott B, Rupp H and Jacob R: Significance of physical exercise in hypertension. Influence of water temperature and beta-blockade on blood pressure, degree of cardiac hypertrophy and cardiac function in swimming training of spontaneously hypertensive rats. Basic Res Cardiol. 81 (Suppl 1):157–169. 1986.PubMed/NCBI

12 

Zimmerman AW and Veerkamp JH: New insights into the structure and function of fatty acid-binding proteins. Cell Mol Life Sci. 59:1096–1116. 2002. View Article : Google Scholar : PubMed/NCBI

13 

Fu Y, Luo N and Lopes-Virella MF: Oxidized LDL induces the expression of ALBP/aP2 mRNA and protein in human THP-1 macrophages. J Lipid Res. 41:2017–2023. 2000.PubMed/NCBI

14 

Haunerland NH and Spener F: Fatty acid-binding proteins-insights from genetic manipulations. Prog Lipid Res. 43:328–349. 2004. View Article : Google Scholar : PubMed/NCBI

15 

Makowski L and Hotamisligil GS: The role of fatty acid binding proteins in metabolic syndrome and atherosclerosis. Curr Opin Lipidol. 16:543–548. 2005. View Article : Google Scholar : PubMed/NCBI

16 

Lin QQ, Lin R, Ji QL, Zhang JY, Wang WR, Yang LN and Zhang KF: Effect of exercise training on renal function and renal aquaporin-2 expression in rats with chronic heart failure. Clin Exp Pharmacol Physiol. 38:179–185. 2011. View Article : Google Scholar : PubMed/NCBI

17 

Quinones QJ, de Ridder GG and Pizzo SV: GRP78: A chaperone with diverse roles beyond the endoplasmic reticulum. Histol Histopathol. 23:1409–1416. 2008.PubMed/NCBI

18 

González B, Hernando R and Manso R: Stress proteins of 70 kDa in chronically exercised skeletal muscle. Pflugers Arch. 440:42–49. 2000. View Article : Google Scholar : PubMed/NCBI

19 

Um HS, Kang EB, Leem YH, Cho IH, Yang CH, Chae KR, Hwang DY and Cho JY: Exercise training acts as a therapeutic strategy for reduction of the pathogenic phenotypes for Alzheimer's disease in an NSE/APPsw-transgenic model. Int J Mol Med. 22:529–539. 2008.PubMed/NCBI

20 

Murlasits Z, Lee Y and Powers SK: Short-term exercise does not increase ER stress protein expression in cardiac muscle. Med Sci Sports Exerc. 39:1522–1528. 2007. View Article : Google Scholar : PubMed/NCBI

21 

Iozzo RV: The family of the small leucine-rich proteoglycans: Key regulators of matrix assembly and cellular growth. Crit Rev Biochem Mol Biol. 32:141–174. 1997. View Article : Google Scholar : PubMed/NCBI

22 

Kampmann A, Fernández B, Deindl E, Kubin T, Pipp F, Eitenmüller I, Hoefer IE, Schaper W and Zimmermann R: The proteoglycan osteoglycin/mimecan is correlated with arteriogenesis. Mol Cell Biochem. 322:15–23. 2009. View Article : Google Scholar : PubMed/NCBI

23 

Shanahan CM, Cary NR, Osbourn JK and Weissberg PL: Identification of osteoglycin as a component of the vascular matrix. Differential expression by vascular smooth muscle cells during neointima formation and in atherosclerotic plaques. Arterioscler Thromb Vasc Biol. 17:2437–2447. 1997. View Article : Google Scholar : PubMed/NCBI

24 

Fernández B, Kampmann A, Pipp F, Zimmermann R and Schaper W: Osteoglycin expression and localization in rabbit tissues and atherosclerotic plaques. Mol Cell Biochem. 246:3–11. 2003. View Article : Google Scholar : PubMed/NCBI

25 

Lea W, Abbas AS, Sprecher H, Vockley J and Schulz H: Long-chain acyl-CoA dehydrogenase is a key enzyme in the mitochondrial beta-oxidation of unsaturated fatty acids. Biochim Biophys Acta. 1485:121–128. 2000. View Article : Google Scholar : PubMed/NCBI

26 

Cox KB, Hamm DA, Millington DS, Matern D, Vockley J, Rinaldo P, Pinkert CA, Rhead WJ, Lindsey JR and Wood PA: Gestational, pathologic and biochemical differences between very long-chain acyl-CoA dehydrogenase deficiency and long-chain acyl-CoA dehydrogenase deficiency in the mouse. Hum Mol Genet. 10:2069–2077. 2001. View Article : Google Scholar : PubMed/NCBI

27 

van Vlies N, Tian L, Overmars H, Bootsma AH, Kulik W, Wanders RJ, Wood PA and Vaz FM: Characterization of carnitine and fatty acid metabolism in the long-chain acyl-CoA dehydrogenase-deficient mouse. Biochem J. 387:185–193. 2005. View Article : Google Scholar : PubMed/NCBI

28 

Jüllig M, Hickey AJ, Chai CC, Skea GL, Middleditch MJ, Costa S, Choong SY, Philips AR and Cooper GJ: Is the failing heart out of fuel or a worn engine running rich? A study of mitochondria in old spontaneously hypertensive rats. Proteomics. 8:2556–2572. 2008. View Article : Google Scholar : PubMed/NCBI

29 

Ciocca DR, Oesterreich S, Chamness GC, McGuire WL and Fuqua SA: Biological and clinical implications of heat shock protein 27,000 (Hsp27): A review. J Natl Cancer Inst. 85:1558–1570. 1993. View Article : Google Scholar : PubMed/NCBI

30 

Ibitayo AI, Sladick J, Tuteja S, Louis-Jacques O, Yamada H, Groblewski G, Welsh M and Bitar KN: HSP27 in signal transduction and association with contractile proteins in smooth muscle cells. Am J Physiol. 277:G445–G454. 1999.PubMed/NCBI

31 

Park HK, Park EC, Bae SW, Park MY, Kim SW, Yoo HS, Tudev M, Ko YH, Choi YH, Kim S, et al: Expression of heat shock protein 27 in human atherosclerotic plaques and increased plasma level of heat shock protein 27 in patients with acute coronary syndrome. Circulation. 114:886–893. 2006. View Article : Google Scholar : PubMed/NCBI

32 

Salinthone S, Tyagi M and Gerthoffer WT: Small heat shock proteins in smooth muscle. Pharmacol Ther. 119:44–54. 2008. View Article : Google Scholar : PubMed/NCBI

33 

Cupp JR and McAlister-Henn L: Cloning and characterization of the gene encoding the IDH1 subunit of NAD(+)-dependent isocitrate dehydrogenase from Saccharomyces cerevisiae. J Biol Chem. 267:16417–16423. 1992.PubMed/NCBI

34 

Keys DA and McAlister-Henn L: Subunit structure, expression, and function of NAD(H)-specific isocitrate dehydrogenase in Saccharomyces cerevisiae. J Bacteriol. 172:4280–4287. 1990.PubMed/NCBI

35 

de Jong L, Elzinga SD, McCammon MT, Grivell LA and van der Spek H: Increased synthesis and decreased stability of mitochondrial translation products in yeast as a result of loss of mitochondrial (NAD(+))-dependent isocitrate dehydrogenase. FEBS Lett. 483:62–66. 2000. View Article : Google Scholar : PubMed/NCBI

36 

Sun B, Wang JH, Lv YY, Zhu SS, Yang J and Ma JZ: Proteomic adaptation to chronic high intensity swimming training in the rat heart. Comp Biochem Physiol Part D Genomics Proteomics. 3:108–117. 2008. View Article : Google Scholar : PubMed/NCBI

37 

Bizeau ME, Willis WT and Hazel JR: Differential responses to endurance training in subsarcolemmal and intermyofibrillar mitochondria. J Appl Physiol (1985). 85:1279–1284. 1998.PubMed/NCBI

38 

Mogensen J, Klausen IC, Pedersen AK, Egeblad H, Bross P, Kruse TA, Gregersen N, Hansen PS, Baandrup U and Borglum AD: Alpha-cardiac actin is a novel disease gene in familial hypertrophic cardiomyopathy. J Clin Invest. 103:R39–R43. 1999. View Article : Google Scholar : PubMed/NCBI

39 

Matsson H, Eason J, Bookwalter CS, Klar J, Gustavsson P, Sunnegårdh J, Enell H, Jonzon A, Vikkula M, Gutierrez I, et al: Alpha-cardiac actin mutations produce atrial septal defects. Hum Mol Genet. 17:256–265. 2008. View Article : Google Scholar : PubMed/NCBI

40 

Mogensen J, Perrot A, Andersen PS, Havndrup O, Klausen IC, Christiansen M, Bross P, Egeblad H, Bundgaard H, Osterziel KJ, et al: Clinical and genetic characteristics of alpha cardiac actin gene mutations in hypertrophic cardiomyopathy. J Med Genet. 41:e102004. View Article : Google Scholar : PubMed/NCBI

41 

Van Breemen C, Aaronson P and Loutzenhiser R: Sodium-calcium interactions in mammalian smooth muscle. Pharmacol Rev. 30:167–208. 1978.PubMed/NCBI

42 

Usui T, Okada M, Hara Y and Yamawaki H: Exploring calmodulin-related proteins, which mediate development of hypertension, in vascular tissues of spontaneous hypertensive rats. Biochem Biophys Res Commun. 405:47–51. 2011. View Article : Google Scholar : PubMed/NCBI

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Copy and paste a formatted citation
Spandidos Publications style
Feng H, Li H, Zhang D, Zhao Y, Jiang N, Zhao X, Zhang Y, Tan J, Fang W, Zhang Y, Zhang Y, et al: Aortic wall proteomic analysis in spontaneously hypertensive rats with a blood pressure decrease induced by 6-week load-free swimming. Biomed Rep 3: 681-686, 2015.
APA
Feng, H., Li, H., Zhang, D., Zhao, Y., Jiang, N., Zhao, X. ... Liu, W. (2015). Aortic wall proteomic analysis in spontaneously hypertensive rats with a blood pressure decrease induced by 6-week load-free swimming. Biomedical Reports, 3, 681-686. https://doi.org/10.3892/br.2015.488
MLA
Feng, H., Li, H., Zhang, D., Zhao, Y., Jiang, N., Zhao, X., Zhang, Y., Tan, J., Fang, W., Zhang, Y., Liu, W."Aortic wall proteomic analysis in spontaneously hypertensive rats with a blood pressure decrease induced by 6-week load-free swimming". Biomedical Reports 3.5 (2015): 681-686.
Chicago
Feng, H., Li, H., Zhang, D., Zhao, Y., Jiang, N., Zhao, X., Zhang, Y., Tan, J., Fang, W., Zhang, Y., Liu, W."Aortic wall proteomic analysis in spontaneously hypertensive rats with a blood pressure decrease induced by 6-week load-free swimming". Biomedical Reports 3, no. 5 (2015): 681-686. https://doi.org/10.3892/br.2015.488
Copy and paste a formatted citation
x
Spandidos Publications style
Feng H, Li H, Zhang D, Zhao Y, Jiang N, Zhao X, Zhang Y, Tan J, Fang W, Zhang Y, Zhang Y, et al: Aortic wall proteomic analysis in spontaneously hypertensive rats with a blood pressure decrease induced by 6-week load-free swimming. Biomed Rep 3: 681-686, 2015.
APA
Feng, H., Li, H., Zhang, D., Zhao, Y., Jiang, N., Zhao, X. ... Liu, W. (2015). Aortic wall proteomic analysis in spontaneously hypertensive rats with a blood pressure decrease induced by 6-week load-free swimming. Biomedical Reports, 3, 681-686. https://doi.org/10.3892/br.2015.488
MLA
Feng, H., Li, H., Zhang, D., Zhao, Y., Jiang, N., Zhao, X., Zhang, Y., Tan, J., Fang, W., Zhang, Y., Liu, W."Aortic wall proteomic analysis in spontaneously hypertensive rats with a blood pressure decrease induced by 6-week load-free swimming". Biomedical Reports 3.5 (2015): 681-686.
Chicago
Feng, H., Li, H., Zhang, D., Zhao, Y., Jiang, N., Zhao, X., Zhang, Y., Tan, J., Fang, W., Zhang, Y., Liu, W."Aortic wall proteomic analysis in spontaneously hypertensive rats with a blood pressure decrease induced by 6-week load-free swimming". Biomedical Reports 3, no. 5 (2015): 681-686. https://doi.org/10.3892/br.2015.488
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