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Review

Moieties in antidiabetic drugs as a target of insulin receptors in association with common neurological disorders (Review)

  • Authors:
    • David Calderón Guzmán
    • Hugo Juárez Olguín
    • Ernestina Hernández García
    • Maribel Ortiz Herrera
    • Norma Osnaya Brizuela
  • View Affiliations / Copyright

    Affiliations: Laboratory of Neurochemistry, National Institute of Pediatrics, Faculty of Medicine, National Autonomous University of Mexico, Mexico City, CP 04530, Mexico, Laboratory of Pharmacology, National Institute of Pediatrics, Faculty of Medicine, National Autonomous University of Mexico, Mexico City, CP 04530, Mexico, Laboratory of Experimental Bacteriology, National Institute of Pediatrics, Faculty of Medicine, National Autonomous University of Mexico, Mexico City, CP 04530, Mexico
  • Pages: 395-399
    |
    Published online on: February 26, 2016
       https://doi.org/10.3892/br.2016.616
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Abstract

Insulin is a peptide that can be harmful with regards to neuroplasticity, neuroprotection and neuromodulation. Furthermore, the role of insulin highlights its relevance in the progress of diverse clinical disorders as well as in the mechanisms associated with certain pathogenesis and their evolution towards diabetes, obesity and neurodegenerative diseases. The precise molecular mechanisms by which these diseases are induced remain to be elucidated. The benefits in knowing/discovering these mechanisms in animal models and humans cannot be undermined. An in depth understanding of the principal risk factors leading to obesity and their management is vital in the implementation of early‑life strategies of intervention and prevention, with a view to avoid adverse late‑life outcomes. Therefore, the aim of the present study was to review their possible association with antidiabetic drugs.
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Copy and paste a formatted citation
Spandidos Publications style
Calderón Guzmán D, Juárez Olguín H, Hernández García E, Ortiz Herrera M and Osnaya Brizuela N: Moieties in antidiabetic drugs as a target of insulin receptors in association with common neurological disorders (Review). Biomed Rep 4: 395-399, 2016.
APA
Calderón Guzmán, D., Juárez Olguín, H., Hernández García, E., Ortiz Herrera, M., & Osnaya Brizuela, N. (2016). Moieties in antidiabetic drugs as a target of insulin receptors in association with common neurological disorders (Review). Biomedical Reports, 4, 395-399. https://doi.org/10.3892/br.2016.616
MLA
Calderón Guzmán, D., Juárez Olguín, H., Hernández García, E., Ortiz Herrera, M., Osnaya Brizuela, N."Moieties in antidiabetic drugs as a target of insulin receptors in association with common neurological disorders (Review)". Biomedical Reports 4.4 (2016): 395-399.
Chicago
Calderón Guzmán, D., Juárez Olguín, H., Hernández García, E., Ortiz Herrera, M., Osnaya Brizuela, N."Moieties in antidiabetic drugs as a target of insulin receptors in association with common neurological disorders (Review)". Biomedical Reports 4, no. 4 (2016): 395-399. https://doi.org/10.3892/br.2016.616
Copy and paste a formatted citation
x
Spandidos Publications style
Calderón Guzmán D, Juárez Olguín H, Hernández García E, Ortiz Herrera M and Osnaya Brizuela N: Moieties in antidiabetic drugs as a target of insulin receptors in association with common neurological disorders (Review). Biomed Rep 4: 395-399, 2016.
APA
Calderón Guzmán, D., Juárez Olguín, H., Hernández García, E., Ortiz Herrera, M., & Osnaya Brizuela, N. (2016). Moieties in antidiabetic drugs as a target of insulin receptors in association with common neurological disorders (Review). Biomedical Reports, 4, 395-399. https://doi.org/10.3892/br.2016.616
MLA
Calderón Guzmán, D., Juárez Olguín, H., Hernández García, E., Ortiz Herrera, M., Osnaya Brizuela, N."Moieties in antidiabetic drugs as a target of insulin receptors in association with common neurological disorders (Review)". Biomedical Reports 4.4 (2016): 395-399.
Chicago
Calderón Guzmán, D., Juárez Olguín, H., Hernández García, E., Ortiz Herrera, M., Osnaya Brizuela, N."Moieties in antidiabetic drugs as a target of insulin receptors in association with common neurological disorders (Review)". Biomedical Reports 4, no. 4 (2016): 395-399. https://doi.org/10.3892/br.2016.616
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