Moieties in antidiabetic drugs as a target of insulin receptors in association with common neurological disorders (Review)

  • Authors:
    • David Calderón Guzmán
    • Hugo Juárez Olguín
    • Ernestina Hernández García
    • Maribel Ortiz Herrera
    • Norma Osnaya Brizuela
  • View Affiliations

  • Published online on: February 26, 2016     https://doi.org/10.3892/br.2016.616
  • Pages: 395-399
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Abstract

Insulin is a peptide that can be harmful with regards to neuroplasticity, neuroprotection and neuromodulation. Furthermore, the role of insulin highlights its relevance in the progress of diverse clinical disorders as well as in the mechanisms associated with certain pathogenesis and their evolution towards diabetes, obesity and neurodegenerative diseases. The precise molecular mechanisms by which these diseases are induced remain to be elucidated. The benefits in knowing/discovering these mechanisms in animal models and humans cannot be undermined. An in depth understanding of the principal risk factors leading to obesity and their management is vital in the implementation of early‑life strategies of intervention and prevention, with a view to avoid adverse late‑life outcomes. Therefore, the aim of the present study was to review their possible association with antidiabetic drugs.
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April-2016
Volume 4 Issue 4

Print ISSN: 2049-9434
Online ISSN:2049-9442

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Spandidos Publications style
Calderón Guzmán D, Juárez Olguín H, Hernández García E, Ortiz Herrera M and Osnaya Brizuela N: Moieties in antidiabetic drugs as a target of insulin receptors in association with common neurological disorders (Review). Biomed Rep 4: 395-399, 2016
APA
Calderón Guzmán, D., Juárez Olguín, H., Hernández García, E., Ortiz Herrera, M., & Osnaya Brizuela, N. (2016). Moieties in antidiabetic drugs as a target of insulin receptors in association with common neurological disorders (Review). Biomedical Reports, 4, 395-399. https://doi.org/10.3892/br.2016.616
MLA
Calderón Guzmán, D., Juárez Olguín, H., Hernández García, E., Ortiz Herrera, M., Osnaya Brizuela, N."Moieties in antidiabetic drugs as a target of insulin receptors in association with common neurological disorders (Review)". Biomedical Reports 4.4 (2016): 395-399.
Chicago
Calderón Guzmán, D., Juárez Olguín, H., Hernández García, E., Ortiz Herrera, M., Osnaya Brizuela, N."Moieties in antidiabetic drugs as a target of insulin receptors in association with common neurological disorders (Review)". Biomedical Reports 4, no. 4 (2016): 395-399. https://doi.org/10.3892/br.2016.616