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Review

Endometriosis research using capture microdissection techniques: Progress and future applications (Review)

  • Authors:
    • Luyang Zhao
    • Chenglei Gu
    • Ke Huang
    • Weidong Han
    • Meng Fu
    • Yuanguang Meng
  • View Affiliations / Copyright

    Affiliations: Department of Gynecology and Obstetrics, Chinese People's Liberation Army (PLA) Medical School, Chinese PLA General Hospital, Beijing 100853, P.R. China, Department of Molecular Biology, Institute of Basic Medicine, PLA Medical School, Chinese PLA General Hospital, Beijing 100853, P.R. China
  • Pages: 531-540
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    Published online on: September 15, 2016
       https://doi.org/10.3892/br.2016.758
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Abstract

Endometriosis is a common gynecological disease with high prevalence, while its etiology and pathophysiology have remained to be fully elucidated. Previous evidence suggested that this disorder may be in part or completely of somatic origin. However, traditional endometrial samples may not be ideal for investigation, as target cells, including epithelial and stromal cells, in endometriotic lesions are too sparse to be analyzed. Recently, capture microdissection techniques have been used to overcome these limitations and eliminate tissue heterogeneity in endometriosis research. Therefore, the present review summarized the alterations in epithelial and stromal cells in endometriosis tissues isolated through capture microdissection, outlined recent progress and provided directions for future investigation of the pathogenesis of endometriosis.
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Copy and paste a formatted citation
Spandidos Publications style
Zhao L, Gu C, Huang K, Han W, Fu M and Meng Y: Endometriosis research using capture microdissection techniques: Progress and future applications (Review). Biomed Rep 5: 531-540, 2016.
APA
Zhao, L., Gu, C., Huang, K., Han, W., Fu, M., & Meng, Y. (2016). Endometriosis research using capture microdissection techniques: Progress and future applications (Review). Biomedical Reports, 5, 531-540. https://doi.org/10.3892/br.2016.758
MLA
Zhao, L., Gu, C., Huang, K., Han, W., Fu, M., Meng, Y."Endometriosis research using capture microdissection techniques: Progress and future applications (Review)". Biomedical Reports 5.5 (2016): 531-540.
Chicago
Zhao, L., Gu, C., Huang, K., Han, W., Fu, M., Meng, Y."Endometriosis research using capture microdissection techniques: Progress and future applications (Review)". Biomedical Reports 5, no. 5 (2016): 531-540. https://doi.org/10.3892/br.2016.758
Copy and paste a formatted citation
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Spandidos Publications style
Zhao L, Gu C, Huang K, Han W, Fu M and Meng Y: Endometriosis research using capture microdissection techniques: Progress and future applications (Review). Biomed Rep 5: 531-540, 2016.
APA
Zhao, L., Gu, C., Huang, K., Han, W., Fu, M., & Meng, Y. (2016). Endometriosis research using capture microdissection techniques: Progress and future applications (Review). Biomedical Reports, 5, 531-540. https://doi.org/10.3892/br.2016.758
MLA
Zhao, L., Gu, C., Huang, K., Han, W., Fu, M., Meng, Y."Endometriosis research using capture microdissection techniques: Progress and future applications (Review)". Biomedical Reports 5.5 (2016): 531-540.
Chicago
Zhao, L., Gu, C., Huang, K., Han, W., Fu, M., Meng, Y."Endometriosis research using capture microdissection techniques: Progress and future applications (Review)". Biomedical Reports 5, no. 5 (2016): 531-540. https://doi.org/10.3892/br.2016.758
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