Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Oncology Letters
      • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Biomedical Reports
      • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • Information for Authors
    • Information for Reviewers
    • Information for Librarians
    • Information for Advertisers
    • Conferences
  • Language Editing
Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • For Authors
    • For Reviewers
    • For Librarians
    • For Advertisers
    • Conferences
  • Language Editing
Login Register Submit
  • This site uses cookies
  • You can change your cookie settings at any time by following the instructions in our Cookie Policy. To find out more, you may read our Privacy Policy.

    I agree
Search articles by DOI, keyword, author or affiliation
Search
Advanced Search
presentation
Biomedical Reports
Join Editorial Board Propose a Special Issue
Print ISSN: 2049-9434 Online ISSN: 2049-9442
Journal Cover
January-2018 Volume 8 Issue 1

Full Size Image

Sign up for eToc alerts
Recommend to Library

Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

Journal Cover
January-2018 Volume 8 Issue 1

Full Size Image

Sign up for eToc alerts
Recommend to Library

  • Article
  • Citations
    • Cite This Article
    • Download Citation
    • Create Citation Alert
    • Remove Citation Alert
    • Cited By
  • Similar Articles
    • Related Articles (in Spandidos Publications)
    • Similar Articles (Google Scholar)
    • Similar Articles (PubMed)
  • Download PDF
  • Download XML
  • View XML
Article

Cardiovascular characteristics of chronic fatigue syndrome

  • Authors:
    • Sara Bozzini
    • Andrea Albergati
    • Enrica Capelli
    • Lorenzo Lorusso
    • Carmine Gazzaruso
    • Gabriele Pelissero
    • Colomba Falcone
  • View Affiliations / Copyright

    Affiliations: Interdepartmental Center for Research in Molecular Medicine (CIRMC), University of Pavia, I-27100 Pavia, Italy, Department of Neurology, Istituti Clinici di Pavia e Vigevano, University Hospital, I-27100 Pavia, Italy, Department of Earth and Environmental Sciences, University of Pavia, I-27100 Pavia, Italy, Department of Neurology, Mellino Mellini Hospital, I-25082 Chiari BS, Italy, IRCCS San Donato Hospital, San Donato Milanese, I-20097 Milan, Italy
  • Pages: 26-30
    |
    Published online on: November 28, 2017
       https://doi.org/10.3892/br.2017.1024
  • Expand metrics +
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Metrics: Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )
Cited By (CrossRef): 0 citations Loading Articles...

This article is mentioned in:



Abstract

Patients with chronic fatigue syndrome (CFS) commonly exhibit orthostatic intolerance. Abnormal sympathetic predominance in the autonomic cardiovascular response to gravitational stimuli was previously described in numerous studies. The aim of the current study was to describe cardiological and clinical characteristics of Italian patients with CFS. All of the patients were of Caucasian ethnicity and had been referred to our center, the Cardiology Department of the University Hospital of Pavia (Pavia, Italy) with suspected CFS. A total of 44 patients with suspected CFS were included in the present study and the diagnosis was confirmed in 19 patients according to recent clinical guidelines. The characteristics at baseline of the population confirm findings from various previous reports regarding the prevalence in females with a female to male ratio of 4:1, the age of onset of the pathology and the presence of previous infection by the Epstein-Barr virus, cytomegalovirus and other human herpesviruses. Despite the current data indicating that the majority of the cardiological parameters investigated are not significantly different in patients with and without CFS, a significant association between the disease and low levels of blood pressure was identified. Other pilot studies revealed a higher prevalence of hypotension and orthostatic intolerance in patients with CFS. Furthermore, many of the CFS symptoms, including fatigue, vertigo, decreased concentration, tremors and nausea, may be explained by hypotension.
View Figures
View References

1 

Fukuda K, Straus SE, Hickie I, Sharpe MC, Dobbins JG and Komaroff A; International Chronic Fatigue Syndrome Study Group, : The chronic fatigue syndrome: A comprehensive approach to its definition and study. Ann Intern Med. 121:953–959. 1994. View Article : Google Scholar : PubMed/NCBI

2 

Brurberg KG, Fønhus MS, Larun L, Flottorp S and Malterud K: Case definitions for chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME): A systematic review. BMJ Open. 4:e0039732014. View Article : Google Scholar : PubMed/NCBI

3 

Fischer DB, William AH, Strauss AC, Unger ER, Jason L, Marshall GD Jr and Dimitrakoff JD: Chronic Fatigue Syndrome: The Current Status and Future Potentials of Emerging Biomarkers. Fatigue. 2:93–109. 2014.PubMed/NCBI

4 

Wyller VB, Saul JP, Walløe L and Thaulow E: Sympathetic cardiovascular control during orthostatic stress and isometric exercise in adolescent chronic fatigue syndrome. Eur J Appl Physiol. 102:623–632. 2008. View Article : Google Scholar : PubMed/NCBI

5 

Meeus M, Goubert D, De Backer F, Struyf F, Hermans L, Coppieters I, De Wandele I, Da Silva H and Calders P: Heart rate variability in patients with fibromyalgia and patients with chronic fatigue syndrome: A systematic review. Semin Arthritis Rheum. 43:279–287. 2013. View Article : Google Scholar : PubMed/NCBI

6 

Miwa K: Cardiac dysfunction and orthostatic intolerance in patients with myalgic encephalomyelitis and a small left ventricle. Heart Vessels. 30:484–489. 2015. View Article : Google Scholar : PubMed/NCBI

7 

Wyller VB, Barbieri R and Saul JP: Blood pressure variability and closed-loop baroreflex assessment in adolescent chronic fatigue syndrome during supine rest and orthostatic stress. Eur J Appl Physiol. 111:497–507. 2011. View Article : Google Scholar : PubMed/NCBI

8 

Falcone C, de Servi S, Poma E, Campana C, Sciré A, Montemartini C and Specchia G: Clinical significance of exercise-induced silent myocardial ischemia in patients with coronary artery disease. J Am Coll Cardiol. 9:295–299. 1987. View Article : Google Scholar : PubMed/NCBI

9 

Turnbull N, Shaw EJ, Baker R, Dunsdon S, Costin N, Britton G, et al: Chronic fatigue syndrome/myalgic encephalomyelitis (or encephalopathy): diagnosis and management of chronic fatigue syndrome/myalgic encephalomyelitis (or encephalopathy) in adults and children. Royal College of General Practitioners, London. 2007.

10 

Reyes M, Gary HE Jr, Dobbins JG, Randall B, Steele L, Fukuda K, Holmes GP, Connell DG, Mawle AC, Schmid DS, et al: Surveillance for chronic fatigue syndrome - four U.S. cities, September 1989 through August 1993. MMWR CDC Surveill Summ. 46:1–13. 1997.PubMed/NCBI

11 

Bansal AS, Bradley AS, Bishop KN, Kiani-Alikhan S and Ford B: Chronic fatigue syndrome, the immune system and viral infection. Brain Behav Immun. 26:24–31. 2012. View Article : Google Scholar : PubMed/NCBI

12 

Underhill RA: Myalgic encephalomyelitis, chronic fatigue syndrome: An infectious disease. Med Hypotheses. 85:765–773. 2015. View Article : Google Scholar : PubMed/NCBI

13 

Jason LA, Richman JA, Rademaker AW, Jordan KM, Plioplys AV, Taylor RR, McCready W, Huang CF and Plioplys S: A community-based study of chronic fatigue syndrome. Arch Intern Med. 159:2129–2137. 1999. View Article : Google Scholar : PubMed/NCBI

14 

Lloyd AR, Hickie I, Boughton CR, Spencer O and Wakefield D: Prevalence of chronic fatigue syndrome in an Australian population. Med J Aust. 153:522–528. 1990.PubMed/NCBI

15 

Lawrie SM and Pelosi AJ: Chronic fatigue syndrome in the community. Prevalence and associations. Br J Psychiatry. 166:793–797. 1995. View Article : Google Scholar : PubMed/NCBI

16 

Johnston SC, Staines DR and Marshall-Gradisnik SM: Epidemiological characteristics of chronic fatigue syndrome/myalgic encephalomyelitis in Australian patients. Clin Epidemiol. 8:97–107. 2016. View Article : Google Scholar : PubMed/NCBI

17 

Glaser R and Kiecolt-Glaser JK: Stress-associated immune modulation: Relevance to viral infections and chronic fatigue syndrome. Am J Med. 105(3A): 35S–42S. 1998. View Article : Google Scholar : PubMed/NCBI

18 

Bozzini S, Boiocchi C, Carlo-Stella N, Ricevuti G and Cuccia M: The possible underworld of Chronic Fatigue Syndrome: From neurotransmitters polymorphisms to disease. J Neurol Res. 2:16–24. 2012.

19 

Pasi A, Bozzini S, Carlo-Stella N, Martinetti M, Bombardieri S, De Silvestri A, Salvaneschi L and Cuccia M: Excess of activating killer cell immunoglobulin like receptors and lack of HLA-Bw4 ligands: A two edged weapon in chronic fatigue syndrome. Mol Med Rep. 4:535–540. 2011.PubMed/NCBI

20 

Carlo-Stella N, Bozzini S, De Silvestri A, Sbarsi I, Pizzochero C, Lorusso L, Martinetti M and Cuccia M: Molecular study of receptor for advanced glycation endproduct gene promoter and identification of specific HLA haplotypes possibly involved in chronic fatigue syndrome. Int J Immunopathol Pharmacol. 22:745–754. 2009. View Article : Google Scholar : PubMed/NCBI

21 

Ortega-Hernandez OD, Cuccia M, Bozzini S, Bassi N, Moscavitch S, Diaz-Gallo LM, Blank M, Agmon-Levin N and Shoenfeld Y: Autoantibodies, polymorphisms in the serotonin pathway, and human leukocyte antigen class II alleles in chronic fatigue syndrome: Are they associated with age at onset and specific symptoms? Ann N Y Acad Sci. 1173:589–599. 2009. View Article : Google Scholar : PubMed/NCBI

22 

van't Leven M, Zielhuis GA, van der Meer JW, Verbeek AL and Bleijenberg G: Fatigue and chronic fatigue syndrome-like complaints in the general population. Eur J Public Health. 20:251–257. 2010. View Article : Google Scholar : PubMed/NCBI

23 

Flores S, Brown A, Adeoye S, Jason LA and Evans M: Examining the impact of obesity on individuals with chronic fatigue syndrome. Workplace Health Saf. 61:299–307. 2013. View Article : Google Scholar : PubMed/NCBI

24 

Wyller VB and Helland IB: Relationship between autonomic cardiovascular control, case definition, clinical symptoms, and functional disability in adolescent chronic fatigue syndrome: An exploratory study. Biopsychosoc Med. 7:52013. View Article : Google Scholar : PubMed/NCBI

25 

Newton JL, Sheth A, Shin J, Pairman J, Wilton K, Burt JA and Jones DE: Lower ambulatory blood pressure in chronic fatigue syndrome. Psychosom Med. 71:361–365. 2009. View Article : Google Scholar : PubMed/NCBI

26 

Frith J, Zalewski P, Klawe JJ, Pairman J, Bitner A, Tafil-Klawe M and Newton JL: Impaired blood pressure variability in chronic fatigue syndrome - a potential biomarker. QJM. 105:831–838. 2012. View Article : Google Scholar : PubMed/NCBI

Related Articles

  • Abstract
  • View
  • Download
  • Twitter
Copy and paste a formatted citation
Spandidos Publications style
Bozzini S, Albergati A, Capelli E, Lorusso L, Gazzaruso C, Pelissero G and Falcone C: Cardiovascular characteristics of chronic fatigue syndrome. Biomed Rep 8: 26-30, 2018.
APA
Bozzini, S., Albergati, A., Capelli, E., Lorusso, L., Gazzaruso, C., Pelissero, G., & Falcone, C. (2018). Cardiovascular characteristics of chronic fatigue syndrome. Biomedical Reports, 8, 26-30. https://doi.org/10.3892/br.2017.1024
MLA
Bozzini, S., Albergati, A., Capelli, E., Lorusso, L., Gazzaruso, C., Pelissero, G., Falcone, C."Cardiovascular characteristics of chronic fatigue syndrome". Biomedical Reports 8.1 (2018): 26-30.
Chicago
Bozzini, S., Albergati, A., Capelli, E., Lorusso, L., Gazzaruso, C., Pelissero, G., Falcone, C."Cardiovascular characteristics of chronic fatigue syndrome". Biomedical Reports 8, no. 1 (2018): 26-30. https://doi.org/10.3892/br.2017.1024
Copy and paste a formatted citation
x
Spandidos Publications style
Bozzini S, Albergati A, Capelli E, Lorusso L, Gazzaruso C, Pelissero G and Falcone C: Cardiovascular characteristics of chronic fatigue syndrome. Biomed Rep 8: 26-30, 2018.
APA
Bozzini, S., Albergati, A., Capelli, E., Lorusso, L., Gazzaruso, C., Pelissero, G., & Falcone, C. (2018). Cardiovascular characteristics of chronic fatigue syndrome. Biomedical Reports, 8, 26-30. https://doi.org/10.3892/br.2017.1024
MLA
Bozzini, S., Albergati, A., Capelli, E., Lorusso, L., Gazzaruso, C., Pelissero, G., Falcone, C."Cardiovascular characteristics of chronic fatigue syndrome". Biomedical Reports 8.1 (2018): 26-30.
Chicago
Bozzini, S., Albergati, A., Capelli, E., Lorusso, L., Gazzaruso, C., Pelissero, G., Falcone, C."Cardiovascular characteristics of chronic fatigue syndrome". Biomedical Reports 8, no. 1 (2018): 26-30. https://doi.org/10.3892/br.2017.1024
Follow us
  • Twitter
  • LinkedIn
  • Facebook
About
  • Spandidos Publications
  • Careers
  • Cookie Policy
  • Privacy Policy
How can we help?
  • Help
  • Live Chat
  • Contact
  • Email to our Support Team