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Review

Nuclear magnetic resonance metabolomics and human liver diseases: The principles and evidence associated with protein and carbohydrate metabolism (Review)

  • Authors:
    • Laurence Le Moyec
    • Mohamed N. Triba
    • Pierre Nahon
    • Nadia Bouchemal
    • Edith Hantz
    • Corentine Goossens
    • Roland Amathieu
    • Philippe Savarin
  • View Affiliations / Copyright

    Affiliations: Unit of Integrative Biology for Exercise Adaptation (UBIAE), University of Evry Val d'Essonne, EA 7362, F‑91025 Evry, France, University of Paris 13, Sorbonne Paris Cité, CSPBAT Laboratory, UMR 7244, CNRS, F‑93000 Bobigny, France, Department of Hepatology, AP‑HP, Hôpital Jean Verdier, F‑93140 Bondy, France
  • Pages: 387-395
    |
    Published online on: March 3, 2017
       https://doi.org/10.3892/br.2017.868
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Abstract

During the last decade, metabolomics has become widely used in the field of human diseases. Numerous studies have demonstrated that this is a powerful technique for improving the understanding, diagnosis and management of various types of liver disease, such as acute and chronic liver diseases, and liver transplantation. Nuclear magnetic resonance (NMR) spectroscopy is one of the two most commonly applied methods for metabolomics. The aim of the present review was to investigate the results from recent key publications focusing on aspects of protein and carbohydrate metabolism. The review includes existing procedures, which are currently used for NMR data acquisition and statistical analysis. In addition, notable results obtained by these studies on protein and carbohydrate metabolism concerning human liver diseases are presented.
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Copy and paste a formatted citation
Spandidos Publications style
Le Moyec L, Triba MN, Nahon P, Bouchemal N, Hantz E, Goossens C, Amathieu R and Savarin P: Nuclear magnetic resonance metabolomics and human liver diseases: The principles and evidence associated with protein and carbohydrate metabolism (Review). Biomed Rep 6: 387-395, 2017.
APA
Le Moyec, L., Triba, M.N., Nahon, P., Bouchemal, N., Hantz, E., Goossens, C. ... Savarin, P. (2017). Nuclear magnetic resonance metabolomics and human liver diseases: The principles and evidence associated with protein and carbohydrate metabolism (Review). Biomedical Reports, 6, 387-395. https://doi.org/10.3892/br.2017.868
MLA
Le Moyec, L., Triba, M. N., Nahon, P., Bouchemal, N., Hantz, E., Goossens, C., Amathieu, R., Savarin, P."Nuclear magnetic resonance metabolomics and human liver diseases: The principles and evidence associated with protein and carbohydrate metabolism (Review)". Biomedical Reports 6.4 (2017): 387-395.
Chicago
Le Moyec, L., Triba, M. N., Nahon, P., Bouchemal, N., Hantz, E., Goossens, C., Amathieu, R., Savarin, P."Nuclear magnetic resonance metabolomics and human liver diseases: The principles and evidence associated with protein and carbohydrate metabolism (Review)". Biomedical Reports 6, no. 4 (2017): 387-395. https://doi.org/10.3892/br.2017.868
Copy and paste a formatted citation
x
Spandidos Publications style
Le Moyec L, Triba MN, Nahon P, Bouchemal N, Hantz E, Goossens C, Amathieu R and Savarin P: Nuclear magnetic resonance metabolomics and human liver diseases: The principles and evidence associated with protein and carbohydrate metabolism (Review). Biomed Rep 6: 387-395, 2017.
APA
Le Moyec, L., Triba, M.N., Nahon, P., Bouchemal, N., Hantz, E., Goossens, C. ... Savarin, P. (2017). Nuclear magnetic resonance metabolomics and human liver diseases: The principles and evidence associated with protein and carbohydrate metabolism (Review). Biomedical Reports, 6, 387-395. https://doi.org/10.3892/br.2017.868
MLA
Le Moyec, L., Triba, M. N., Nahon, P., Bouchemal, N., Hantz, E., Goossens, C., Amathieu, R., Savarin, P."Nuclear magnetic resonance metabolomics and human liver diseases: The principles and evidence associated with protein and carbohydrate metabolism (Review)". Biomedical Reports 6.4 (2017): 387-395.
Chicago
Le Moyec, L., Triba, M. N., Nahon, P., Bouchemal, N., Hantz, E., Goossens, C., Amathieu, R., Savarin, P."Nuclear magnetic resonance metabolomics and human liver diseases: The principles and evidence associated with protein and carbohydrate metabolism (Review)". Biomedical Reports 6, no. 4 (2017): 387-395. https://doi.org/10.3892/br.2017.868
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