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July-2017 Volume 7 Issue 1

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International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

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International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

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Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

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Review

Personalized medicine could transform healthcare (Review)

  • Authors:
    • Sunil Mathur
    • Joseph Sutton
  • View Affiliations / Copyright

    Affiliations: Molecular Drug Research Laboratory, Edinburgh Napier University, Edinburgh EH11 4BN, UK
  • Pages: 3-5
    |
    Published online on: June 2, 2017
       https://doi.org/10.3892/br.2017.922
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Abstract

Personalized medicine (PM) is about tailoring a treatment as individualized as the disease. The approach relies on identifying genetic, epigenomic, and clinical information that allows the breakthroughs in our understanding of how a person’s unique genomic portfolio makes them vulnerable to certain diseases. PM approach is a complete extension of traditional approach (One-Size-Fits-All) to increasing our ability to predict which medical treatments will be safe and effective for individual patient, and which ones will not be, based on the patient’s unique genetic profile. Implementation of PM has the potential to reduce financial and time expenditure, and increase quality of life and life extension of patients. Knowledge of PM facilitates earlier disease detection via enhanced use of existing biomarkers and detection of early genomic and epigenomic events in disease development, particularly carcinogenesis. The PM approach predominantly focuses on preventative medicine and favours taking pro-active actions rather than just reactive. This approach delays or prevents the need to apply more severe treatments which are usually less tolerated and with increased quality of life and financial considerations. Increasing healthcare costs have placed additional pressure on government funded healthcare systems globally, especially regarding end of life care. PM may increase the effectiveness of existing treatments and negate the inherent problems associated with non-PM approaches. PM is a young but rapidly expanding field of healthcare where a physician can select a treatment based on a patient’s genetic profile that may not only minimize harmful side effects and guarantee a more successful result, but can be less cost effective compared with a ‘trial-and-error’ approach to disease treatment. The less efficient non-PM (‘trial-and-error’) approach, which can lead to drug toxicity, severe side effects, reactive treatment and misdiagnosis continue to contribute to increasing healthcare costs. Increased patient stratification will allow for the enhanced application of PM and pro-active treatment regimens, resulting in reduced costs and quality of life enhancement.
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Copy and paste a formatted citation
Spandidos Publications style
Mathur S and Sutton J: Personalized medicine could transform healthcare (Review). Biomed Rep 7: 3-5, 2017.
APA
Mathur, S., & Sutton, J. (2017). Personalized medicine could transform healthcare (Review). Biomedical Reports, 7, 3-5. https://doi.org/10.3892/br.2017.922
MLA
Mathur, S., Sutton, J."Personalized medicine could transform healthcare (Review)". Biomedical Reports 7.1 (2017): 3-5.
Chicago
Mathur, S., Sutton, J."Personalized medicine could transform healthcare (Review)". Biomedical Reports 7, no. 1 (2017): 3-5. https://doi.org/10.3892/br.2017.922
Copy and paste a formatted citation
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Spandidos Publications style
Mathur S and Sutton J: Personalized medicine could transform healthcare (Review). Biomed Rep 7: 3-5, 2017.
APA
Mathur, S., & Sutton, J. (2017). Personalized medicine could transform healthcare (Review). Biomedical Reports, 7, 3-5. https://doi.org/10.3892/br.2017.922
MLA
Mathur, S., Sutton, J."Personalized medicine could transform healthcare (Review)". Biomedical Reports 7.1 (2017): 3-5.
Chicago
Mathur, S., Sutton, J."Personalized medicine could transform healthcare (Review)". Biomedical Reports 7, no. 1 (2017): 3-5. https://doi.org/10.3892/br.2017.922
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