Clinical presentation and treatment of gastric metastasis from other malignancies of solid organs

Namikawa,Tsutomu; Munekage,Eri; Ogawa,Maho; Oki,Toyokazu; Munekage,Masaya; Maeda,Hiromichi; Kitagawa,Hiroyuki; Sugimoto,Takeki; Kobayashi,Michiya; Hanazaki,Kazuhiro

doi:10.3892/br.2017.943

August-2017 Volume 7 Issue 2

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August-2017 Volume 7 Issue 2

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Article

Clinical presentation and treatment of gastric metastasis from other malignancies of solid organs

Authors:
- Tsutomu Namikawa
- Eri Munekage
- Maho Ogawa
- Toyokazu Oki
- Masaya Munekage
- Hiromichi Maeda
- Hiroyuki Kitagawa
- Takeki Sugimoto
- Michiya Kobayashi
- Kazuhiro Hanazaki
View Affiliations / Copyright

Affiliations: Department of Surgery, Kochi Medical School, Nankoku, Kochi 783‑8505, Japan, Cancer Treatment Center, Kochi Medical School, Nankoku, Kochi 783‑8505, Japan
Pages: 159-162
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Published online on: July 6, 2017

https://doi.org/10.3892/br.2017.943
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Abstract

The aim of the present study was to analyze the clinicopathologic features and treatment outcomes of gastric metastasis from other malignancies of solid organs. A review was conducted of patients with metastatic tumors in the stomach from other malignancies of solid organs detected endoscopically at the Department of Surgery, Kochi Medical School, from January 1991 to December 2015. Seven patients (four men and three women), with a median age of 64 years (range, 42‑71 years), had metastatic gastric tumors. Median tumor size was 7.3 cm (range, 2.5‑12.0 cm). The primary malignancy leading to metastatic tumors in the stomach was esophageal cancer in three patients, breast cancer in two patients, renal cell carcinoma in one patient, and ovarian cancer in one patient. Gastric metastasis presented as solitary lesions in six patients and as multiple lesions in one patient. Four patients had solitary gastric metastasis, whereas three had multiple metastases in other organs. The median tumor size was significantly smaller in patients with solitary rather than multiple metastases (4.6 vs. 12.0 cm, respectively; P=0.038). Three patients received systemic therapy and four underwent surgical resection of the metastatic tumor, and of these, only one was alive 58 months after surgery. Clinicians should be aware of the possible existence of metastatic gastric cancer, especially in breast carcinoma and esophageal cancer. Surgical resection may considerably improve patients' quality of life, and could be of benefit when there is a risk of bleeding and/or a solitary metastasis.

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Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

Clinical presentation and treatment of gastric metastasis from other malignancies of solid organs

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