Subungual onychomycosis due to Aspergillus niger mimicking a glomus tumor: A case report

Matsuyama,Yumi; Nakamura,Tomoki; Hagi,Tomohito; Asanuma,Kunihiro; Sudo,Akihiro

doi:10.3892/br.2017.994

December-2017 Volume 7 Issue 6

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December-2017 Volume 7 Issue 6

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Case Report

Subungual onychomycosis due to Aspergillus niger mimicking a glomus tumor: A case report

Authors:
- Yumi Matsuyama
- Tomoki Nakamura
- Tomohito Hagi
- Kunihiro Asanuma
- Akihiro Sudo
View Affiliations / Copyright

Affiliations: Department of Orthopaedic Surgery, Mie University Graduate School of Medicine, Edobashi, Tsu-city, Mie 514-8507, Japan
Pages: 532-534
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Published online on: September 29, 2017

https://doi.org/10.3892/br.2017.994
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Abstract

Onychomycosis is a common nail infection caused by dermatophytes, while non-dermatophytes including Aspergillus spp. are causes of nail onychomycosis. Aspergillus niger is not common as a cause of nail onychomycosis. In the current study we present a 60-year-old woman with subungual onychomycosis due to Aspergillus niger mimicking a glomus tumor. Physical examination revealed right thumb had a black color of nail bed. Localized tenderness and severe pain were observed. However, the cold sensitivity test, Love's pin test and Hildreth's test were negative. On radiograph, bone erosion was found in a part of distal phalanx at the right thumb. Magnetic resonance imaging identified a mass at the subungual space, which exhibited low signal intensity on T1-weighted images and high signal intensity on T2-weighted images. The differential diagnosis included glomus tumor and infection. The histological findings demonstrated dichotomous septate hyphae. The culture was positive for Aspergillus niger. The results suggested that when physical examination is not typical for a glomus tumor, other diseases may be considered. Additionally, frozen section diagnosis may be useful.

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Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

Subungual onychomycosis due to Aspergillus niger mimicking a glomus tumor: A case report

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