An infant presenting with Kawasaki disease following immunization for influenza: A case report

Jeong,Seung Woo; Kim,Do Hee; Han,Mi Young; Cha,Sung‑Ho; Yoon,Kyung Lim

doi:10.3892/br.2018.1043

March-2018 Volume 8 Issue 3

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March-2018 Volume 8 Issue 3

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Case Report

An infant presenting with Kawasaki disease following immunization for influenza: A case report

Authors:
- Seung Woo Jeong
- Do Hee Kim
- Mi Young Han
- Sung‑Ho Cha
- Kyung Lim Yoon
View Affiliations / Copyright

Affiliations: Department of Pediatrics, Kyung Hee University Hospital at Gangdong, Kyung Hee University School of Medicine, Seoul 05278, Republic of Korea, Department of Pediatrics, Kyung Hee University Hospital, Kyung Hee University School of Medicine, Seoul 02447, Republic of Korea
Pages: 301-303
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Published online on: January 16, 2018

https://doi.org/10.3892/br.2018.1043
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Abstract

Kawasaki disease (KD) is a childhood vascular disorder of unknown etiology. Concerns have recently been raised regarding vaccinations as a potential risk factor for KD. In addition, various forms of vasculitis have been reported as adverse events following administration after various vaccines. Patients exhibiting post vaccination KD have previously been described; however, thus far, to the best of our knowledge, only one patient exhibiting post influenza vaccination KD has been reported in Japan. The present study describes a case of KD 24 h after immunization with influenza in an infant (age, 18 months) following 6 days of high fever, a body rash that had persisted for 2 days and nonsuppurative bilateral conjunctivitis. To the best of the authors' knowledge, this is the first reported case in Korea and the present study reviews various recent studies regarding vasculitis following vaccination and the causal association between them.

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1	Sundel RP and Petty RE: Kasawaki diseaseTextbook of Pediatric Rheumatology. 6th. Classidy JT, Laxer RM, Petty RE and Lindsley CB: Elsevier Saunders; Philadelphia: pp. 505–520. 2011, View Article : Google Scholar
2	Miron D, Fink D and Hashkes PJ: Kawasaki disease in an infant following immunisation with hepatitis B vaccine. Clin Rheumatol. 22:461–463. 2003. View Article : Google Scholar
3	Schmöeller D, Keiserman MW, Staub HL, Velho FP and de Fátima Grohe M: Yellow fever vaccination and Kawasaki disease. Pediatr Infect Dis J. 28:1037–1038. 2009. View Article : Google Scholar
4	Shimada S, Watanabe T and Sato S: A Patient with Kawasaki Disease Following Influenza Vaccinations. Pediatr Infect Dis J. 34:9132015. View Article : Google Scholar
5	Bonetto C, Trotta F, Felicetti P, Alarcón GS, Santuccio C, Bachtiar NS, Pernus YB, Chandler R, Girolomoni G, Hadden RDM, et al: Vasculitis as an adverse event following immunization-Systematic literature review. Vaccine. 2015.
6	Abrams JY, Weintraub ES, Baggs JM, McCarthy NL, Schonberger LB, Lee GM, Klein NP, Belongia EA, Jackson ML, Naleway AL, et al: Childhood vaccines and Kawasaki disease, Vaccine Safety Datalink, 1996–2006. Vaccine. 33:382–387. 2015. View Article : Google Scholar
7	Zafrir Y, Agmon-Levin N and Shoenfeld Y: Post-influenza vaccination vasculitides: A possible new entity. J Clin Rheumatol. 15:269–270. 2009. View Article : Google Scholar
8	Hoffman GS and Calabrese LH: Vasculitis: Determinants of disease patterns. Nat Rev Rheumatol. 10:454–462. 2014. View Article : Google Scholar
9	Guillevin L: Infections in vasculitis. Best Pract Res Clin Rheumatol. 27:19–31. 2013. View Article : Google Scholar
10	Principi N, Rigante D and Esposito S: The role of infection in Kawasaki syndrome. J Infect. 67:1–10. 2013. View Article : Google Scholar

Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

An infant presenting with Kawasaki disease following immunization for influenza: A case report

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Abstract

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