Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Oncology Letters
      • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Biomedical Reports
      • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • Information for Authors
    • Information for Reviewers
    • Information for Librarians
    • Information for Advertisers
    • Conferences
  • Language Editing
Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • For Authors
    • For Reviewers
    • For Librarians
    • For Advertisers
    • Conferences
  • Language Editing
Login Register Submit
  • This site uses cookies
  • You can change your cookie settings at any time by following the instructions in our Cookie Policy. To find out more, you may read our Privacy Policy.

    I agree
Search articles by DOI, keyword, author or affiliation
Search
Advanced Search
presentation
Biomedical Reports
Join Editorial Board Propose a Special Issue
Print ISSN: 2049-9434 Online ISSN: 2049-9442
Journal Cover
November-2018 Volume 9 Issue 5

Full Size Image

Sign up for eToc alerts
Recommend to Library

Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

Journal Cover
November-2018 Volume 9 Issue 5

Full Size Image

Sign up for eToc alerts
Recommend to Library

  • Article
  • Citations
    • Cite This Article
    • Download Citation
    • Create Citation Alert
    • Remove Citation Alert
    • Cited By
  • Similar Articles
    • Related Articles (in Spandidos Publications)
    • Similar Articles (Google Scholar)
    • Similar Articles (PubMed)
  • Download PDF
  • Download XML
  • View XML
Review Open Access

Understanding psoriasis: Role of miRNAs (Review)

  • Authors:
    • Teodora Larisa Timis
    • Remus Ioan Orasan
  • View Affiliations / Copyright

    Affiliations: Department of Physiology, 'Iuliu Hatieganu' University of Medicine and Pharmacy, 400006 Cluj-Napoca, Romania
    Copyright: © Timis et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Pages: 367-374
    |
    Published online on: September 11, 2018
       https://doi.org/10.3892/br.2018.1146
  • Expand metrics +
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Metrics: Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )
Cited By (CrossRef): 0 citations Loading Articles...

This article is mentioned in:



Abstract

Psoriasis is a chronic, immune-mediated inflammatory skin disease, with a multifactorial etiology and important immunologic, genetic and environmental components. Psoriasis vulgaris represents its most common form, with a variable prevalence across the globe. Although its pathogenesis remains to be fully elucidated, a lack of balance in the epigenetic network has been shown to trigger certain elements of this disease, possibly altering its outcome. MicroRNAs are small non-coding RNA molecules involved in RNA-silencing and the post-transcriptional regulation of gene expression, which also appear to mediate the immune dysfunction in psoriasis. Although microRNA research is a new field in dermatology and psoriasis, there is rapidly accumulating evidence for its major contribution in the pathogenesis of chronic inflammatory conditions, including psoriasis and other dermatological disorders. Furthermore, circulating miRNAs identified in patients' blood samples have been identified as promising biomarkers of diagnosis, prognosis or treatment response. Extended investigations in this field are required, as until now, the exact involvement of miRNAs in psoriasis have remained to be entirely elucidated. This short review highlights a number of the roles of miRNAs found in different stages of psoriasis.
View Figures

Figure 1

Figure 2

Figure 3

Figure 4

Figure 5

View References

1 

Nestle FO, Kaplan DH and Barker J: Psoriasis. N Engl J Med. 361:496–509. 2009. View Article : Google Scholar : PubMed/NCBI

2 

Gudjonsson JE and Elder JT: Psoriasis: Epidemiology. Clin Dermatol. 25:535–546. 2007. View Article : Google Scholar : PubMed/NCBI

3 

Huang RY, Li L, Wang MJ, Chen XM, Huang QC and Lu CJ: An Exploration of the role of MicroRNAs in psoriasis: A systematic review of the literature. Medicine (Baltimore). 94:e20302015. View Article : Google Scholar : PubMed/NCBI

4 

Ortega C, Fernández-A S, Carrillo JM, Romero P, Molina IJ, Moreno JC and Santamaría M: IL-17-producing CD8+ T lymphocytes from psoriasis skin plaques are cytotoxic effector cells that secrete Th17-related cytokines. J Leukoc Biol. 86:435–443. 2009. View Article : Google Scholar : PubMed/NCBI

5 

Ross K: Towards topical microRNA-directed therapy for epidermal disorders. J Control Release. 269:136–147. 2018. View Article : Google Scholar : PubMed/NCBI

6 

Soltanzadeh-Yamchi M, Shahbazi M, Aslani S and Mohammadnia-Afrouzi M: MicroRNA signature of regulatory T cells in health and autoimmunity. Biomed Pharmacother. 100:316–323. 2018. View Article : Google Scholar : PubMed/NCBI

7 

Ruksha TG, Komina AV and Palkina NV: MicroRNA in skin diseases. Eur J Dermatol. 27:343–352. 2017.PubMed/NCBI

8 

Liu Y and Liu Q: MicroRNAs as regulatory elements in psoriasis. Open Med (Wars). 11:336–340. 2016.PubMed/NCBI

9 

Barca-Mayo O and Lu QR: Fine-tuning oligodendrocyte development by microRNAs. Front Neurosci. 6:132012. View Article : Google Scholar : PubMed/NCBI

10 

Hawkes JE, Nguyen GH, Fujita M, Florell SR, Callis Duffin K, Krueger GG and O'Connell RM: microRNAs in psoriasis. J Invest Dermatol. 136:365–371. 2016. View Article : Google Scholar : PubMed/NCBI

11 

Jiang M, Sun Z, Dang E, Li B, Fang H, Li J, Gao L, Zhang K and Wang G: TGFβ/SMAD/microRNA-486-3p signaling axis mediates keratin 17 expression and keratinocyte hyperproliferation in psoriasis. J Invest Dermatol. 137:2177–2186. 2017. View Article : Google Scholar : PubMed/NCBI

12 

Degueurce G, D'Errico I, Pich C, Ibberson M, Schütz F, Montagner A, Sgandurra M, Mury L, Jafari P, Boda A, et al: Identification of a novel PPARβ/δ/miR-21-3p axis in UV-induced skin inflammation. EMBO Mol Med. 8:919–936. 2016. View Article : Google Scholar : PubMed/NCBI

13 

Boele J, Persson H, Shin JW, Ishizu Y, Newie IS, Søkilde R, Hawkins SM, Coarfa C, Ikeda K, Takayama K, et al: PAPD5-mediated 3 adenylation and subsequent degradation of miR-21 is disrupted in proliferative disease. Proc Natl Acad Sci USA. 111:11467–11472. 2014. View Article : Google Scholar : PubMed/NCBI

14 

Guinea-Viniegra J, Jiménez M, Schonthaler HB, Navarro R, Delgado Y, Concha-Garzón MJ, Tschachler E, Obad S, Daudén E and Wagner EF: Targeting miR-21 to treat psoriasis. Sci Transl Med. 6:225re12014. View Article : Google Scholar : PubMed/NCBI

15 

Masalha M, Sidi Y and Avni D: The contribution of feedback loops between miRNAs, cytokines and growth factors to the pathogenesis of psoriasis. Exp Dermatol. 27:603–610. 2018. View Article : Google Scholar : PubMed/NCBI

16 

Stepicheva NA and Song JL: Function and regulation of microRNA-31 in development and disease. Mol Reprod Dev. 83:654–674. 2016. View Article : Google Scholar : PubMed/NCBI

17 

Yan S, Xu Z, Lou F, Zhang L, Ke F, Bai J, Liu Z, Liu J, Wang H, Zhu H, et al: NF-κB-induced microRNA-31 promotes epidermal hyperplasia by repressing protein phosphatase 6 in psoriasis. Nat Commun. 6:76522015. View Article : Google Scholar : PubMed/NCBI

18 

Xu N, Meisgen F, Butler LM, Han G, Wang XJ, Söderberg-Nauclér C, Ståhle M, Pivarcsi A and Sonkoly E: MicroRNA-31 is overexpressed in psoriasis and modulates inflammatory cytokine and chemokine production in keratinocytes via targeting serine/threonine kinase 40. J Immunol. 190:678–688. 2013. View Article : Google Scholar : PubMed/NCBI

19 

Hermann H, Runnel T, Aab A, Baurecht H, Rodriguez E, Magilnick N, Urgard E, Šahmatova L, Prans E, Maslovskaja J, et al: miR-146b probably assists miRNA-146a in the suppression of keratinocyte proliferation and inflammatory responses in psoriasis. J Invest Dermatol. 137:1945–1954. 2017. View Article : Google Scholar : PubMed/NCBI

20 

Ichihara A, Jinnin M, Yamane K, Fujisawa A, Sakai K, Masuguchi S, Fukushima S, Maruo K and Ihn H: microRNA-mediated keratinocyte hyperproliferation in psoriasis vulgaris. Br J Dermatol. 165:1003–1010. 2011. View Article : Google Scholar : PubMed/NCBI

21 

Zibert JR, Løvendorf MB, Litman T, Olsen J, Kaczkowski B and Skov L: MicroRNAs and potential target interactions in psoriasis. J Dermatol Sci. 58:177–185. 2010. View Article : Google Scholar : PubMed/NCBI

22 

Srivastava A, Nikamo P, Lohcharoenkal W, Li D, Meisgen F, Xu Landén N, Ståhle M, Pivarcsi A and Sonkoly E: MicroRNA-146a suppresses IL-17-mediated skin inflammation and is genetically associated with psoriasis. J Allergy Clin Immunol. 139:550–561. 2017. View Article : Google Scholar : PubMed/NCBI

23 

Pivarcsi A, Ståhle M and Sonkoly E: Genetic polymorphisms altering microRNA activity in psoriasis - a key to solve the puzzle of missing heritability? Exp Dermatol. 23:620–624. 2014. View Article : Google Scholar : PubMed/NCBI

24 

Guo Q, Zhang J, Li J, Zou L, Zhang J, Xie Z, Fu X, Jiang S, Chen G, Jia Q, et al: Forced miR-146a expression causes autoimmune lymphoproliferative syndrome in mice via downregulation of Fas in germinal center B cells. Blood. 121:4875–4883. 2013. View Article : Google Scholar : PubMed/NCBI

25 

Xia P, Fang X, Zhang ZH, Huang Q, Yan KX, Kang KF, Han L and Zheng ZZ: Dysregulation of miRNA146a versus IRAK1 induces IL-17 persistence in the psoriatic skin lesions. Immunol Lett. 148:151–162. 2012. View Article : Google Scholar : PubMed/NCBI

26 

Chatzikyriakidou A, Voulgari PV, Georgiou I and Drosos AA: The role of microRNA-146a (miR-146a) and its target IL-1R-associated kinase (IRAK1) in psoriatic arthritis susceptibility. Scand J Immunol. 71:382–385. 2010. View Article : Google Scholar : PubMed/NCBI

27 

Shams K, Kurowska-Stolarska M, Schütte F, Burden AD, McKimmie CS and Graham GJ: MicroRNA-146 and cell trauma down-regulate expression of the psoriasis-associated atypical chemokine receptor ACKR2. J Biol Chem. 293:3003–3012. 2018. View Article : Google Scholar : PubMed/NCBI

28 

Hou RX, Liu RF, Zhao XC, Jia YR, An P, Hao ZP, Li JQ, Li XH, Yin GH and Zhang KM: Increased miR-155-5p expression in dermal mesenchymal stem cells of psoriatic patients: Comparing the microRNA expression profile by microarray. Genet Mol Res. Sep 2–2016.(Epub ahead of print). doi: 10.4238/gmr.15038631. View Article : Google Scholar

29 

García-Rodríguez S, Arias-Santiago S, Blasco-Morente G, Orgaz-Molina J, Rosal-Vela A, Navarro P, Magro-Checa C, Martínez-López A, Ruiz JC, Raya E, et al: Increased expression of microRNA-155 in peripheral blood mononuclear cells from psoriasis patients is related to disease activity. J Eur Acad Dermatol Venereol. 31:312–322. 2017. View Article : Google Scholar : PubMed/NCBI

30 

Xu L and Leng H, Shi X, Ji J, Fu J and Leng H: miR-155 promotes cell proliferation and inhibits apoptosis by PTEN signaling pathway in the psoriasis. Biomed Pharmacother. 90:524–530. 2017. View Article : Google Scholar : PubMed/NCBI

31 

Xu Y, Ji Y, Lan X, Gao X, Chen HD and Geng L: miR 203 contributes to IL 17 induced VEGF secretion by targeting SOCS3 in keratinocytes. Mol Med Rep. 16:8989–8996. 2017. View Article : Google Scholar : PubMed/NCBI

32 

Primo MN, Bak RO, Schibler B and Mikkelsen JG: Regulation of pro-inflammatory cytokines TNFα and IL24 by microRNA-203 in primary keratinocytes. Cytokine. 60:741–748. 2012. View Article : Google Scholar : PubMed/NCBI

33 

Xu N, Brodin P, Wei T, Meisgen F, Eidsmo L, Nagy N, Kemeny L, Ståhle M, Sonkoly E and Pivarcsi A: miR-125b, a microRNA downregulated in psoriasis, modulates keratinocyte proliferation by targeting FGFR2. J Invest Dermatol. 131:1521–1529. 2011. View Article : Google Scholar : PubMed/NCBI

34 

Wei T, Folkersen L, Biskup E, Xu N, Manfe V, Niazi O and Gniadecki R: Ubiquitin-specific peptidase 2 as a potential link between microRNA-125b and psoriasis. Br J Dermatol. 176:723–731. 2017. View Article : Google Scholar : PubMed/NCBI

35 

Wang MJ, Xu YY, Huang RY, Chen XM, Chen HM, Han L, Yan YH and Lu CJ: Role of an imbalanced miRNAs axis in pathogenesis of psoriasis: Novel perspectives based on review of the literature. Oncotarget. 8:5498–5507. 2017.PubMed/NCBI

36 

Lerman G, Avivi C, Mardoukh C, Barzilai A, Tessone A, Gradus B, Pavlotsky F, Barshack I, Polak-Charcon S, Orenstein A, et al: MiRNA expression in psoriatic skin: Reciprocal regulation of hsa-miR-99a and IGF-1R. PLoS One. 6:e209162011. View Article : Google Scholar : PubMed/NCBI

37 

Lerman G, Sharon M, Leibowitz-Amit R, Sidi Y and Avni D: The crosstalk between IL-22 signaling and miR-197 in human keratinocytes. PLoS One. 9:e1074672014. View Article : Google Scholar : PubMed/NCBI

38 

Elharrar E, Masalha M, Lerman G, Leibowitz-Amit R, Kassem R, Harats M, Sidi Y and Avni D: Positive-negative feedback loop between MiR-197 and IL-17A signaling in human keratinocytes. Immunome Res. May 2–2016.(Epub ahead of print). doi: 10.4172/1745-7580.10000111. View Article : Google Scholar

39 

Wang R, Zhao Z, Zheng L, Xing X, Ba W, Zhang J, Huang M, Zhu W, Liu B, Meng X, et al: MicroRNA-520a suppresses the proliferation and mitosis of HaCaT cells by inactivating protein kinase B. Exp Ther Med. 14:6207–6212. 2017.PubMed/NCBI

40 

Wang X, Wang P, Zhu Y, Zhang Z, Zhang J and Wang H: MicroRNA-520a attenuates proliferation of Raji cells through inhibition of AKT1/NF-κB and PERK/eIF2α signaling pathway. Oncol Rep. 36:1702–1708. 2016. View Article : Google Scholar : PubMed/NCBI

41 

Van Gele M, Bracke S, de Medeiros Alves AK and Lambert J: Exploring the feasibility of whole blood to identify systemic miRNA biomarkers for patients with moderate to severe psoriasis. Eur J Dermatol. 26:195–198. 2016.PubMed/NCBI

42 

Liu Q, Wu DH, Han L, Deng JW, Zhou L, He R, Lu CJ and Mi QS: Roles of microRNAs in psoriasis: Immunological functions and potential biomarkers. Exp Dermatol. 26:359–367. 2017. View Article : Google Scholar : PubMed/NCBI

43 

Sonkoly E, Wei T, Janson PC, Sääf A, Lundeberg L, Tengvall-Linder M, Norstedt G, Alenius H, Homey B, Scheynius A, et al: MicroRNAs: Novel regulators involved in the pathogenesis of psoriasis? PLoS One. 2:e6102007. View Article : Google Scholar : PubMed/NCBI

Related Articles

  • Abstract
  • View
  • Download
  • Twitter
Copy and paste a formatted citation
Spandidos Publications style
Timis TL and Orasan RI: Understanding psoriasis: Role of miRNAs (Review). Biomed Rep 9: 367-374, 2018.
APA
Timis, T.L., & Orasan, R.I. (2018). Understanding psoriasis: Role of miRNAs (Review). Biomedical Reports, 9, 367-374. https://doi.org/10.3892/br.2018.1146
MLA
Timis, T. L., Orasan, R. I."Understanding psoriasis: Role of miRNAs (Review)". Biomedical Reports 9.5 (2018): 367-374.
Chicago
Timis, T. L., Orasan, R. I."Understanding psoriasis: Role of miRNAs (Review)". Biomedical Reports 9, no. 5 (2018): 367-374. https://doi.org/10.3892/br.2018.1146
Copy and paste a formatted citation
x
Spandidos Publications style
Timis TL and Orasan RI: Understanding psoriasis: Role of miRNAs (Review). Biomed Rep 9: 367-374, 2018.
APA
Timis, T.L., & Orasan, R.I. (2018). Understanding psoriasis: Role of miRNAs (Review). Biomedical Reports, 9, 367-374. https://doi.org/10.3892/br.2018.1146
MLA
Timis, T. L., Orasan, R. I."Understanding psoriasis: Role of miRNAs (Review)". Biomedical Reports 9.5 (2018): 367-374.
Chicago
Timis, T. L., Orasan, R. I."Understanding psoriasis: Role of miRNAs (Review)". Biomedical Reports 9, no. 5 (2018): 367-374. https://doi.org/10.3892/br.2018.1146
Follow us
  • Twitter
  • LinkedIn
  • Facebook
About
  • Spandidos Publications
  • Careers
  • Cookie Policy
  • Privacy Policy
How can we help?
  • Help
  • Live Chat
  • Contact
  • Email to our Support Team