Epigenetic modulation during hippocampal development (Review)

  • Authors:
    • Si‑Jing Fan
    • An‑Bang Sun
    • Lian Liu
  • View Affiliations

  • Published online on: October 18, 2018     https://doi.org/10.3892/br.2018.1160
  • Pages: 463-473
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Abstract

The hippocampus is located in the limbic system and is vital in learning ability, memory formation and emotion regulation, and is associated with depression, epilepsy and mental retardation in an abnormal developmental situation. Several factors have been found to modulate the development of the hippocampus, and epigenetic modification have a crucial effect in this progress. The present review summarizes the epigenetic modifications, including DNA methylation, histone acetylation, and non‑coding RNAs, regulating all stages of hippocampal development, focusing on the growth of Ammon's horn and the dentate gyrus in humans and rodents. These modifications may significantly affect hippocampal development and health in addition to cognitive processes.
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December-2018
Volume 9 Issue 6

Print ISSN: 2049-9434
Online ISSN:2049-9442

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Spandidos Publications style
Fan SJ, Sun AB and Liu L: Epigenetic modulation during hippocampal development (Review). Biomed Rep 9: 463-473, 2018
APA
Fan, S., Sun, A., & Liu, L. (2018). Epigenetic modulation during hippocampal development (Review). Biomedical Reports, 9, 463-473. https://doi.org/10.3892/br.2018.1160
MLA
Fan, S., Sun, A., Liu, L."Epigenetic modulation during hippocampal development (Review)". Biomedical Reports 9.6 (2018): 463-473.
Chicago
Fan, S., Sun, A., Liu, L."Epigenetic modulation during hippocampal development (Review)". Biomedical Reports 9, no. 6 (2018): 463-473. https://doi.org/10.3892/br.2018.1160