Open Access

Advantages and challenges of stem cell therapy for osteoarthritis (Review)

  • Authors:
    • Stephanie Jyet Quan Loo
    • Nyet Kui Wong
  • View Affiliations

  • Published online on: June 10, 2021     https://doi.org/10.3892/br.2021.1443
  • Article Number: 67
  • Copyright: © Loo et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

Osteoarthritis (OA) is a degenerative disorder of the cartilage and is one of the leading causes of disability, particularly amongst the elderly, wherein patients with advanced‑stage OA experience chronic pain and functional impairment of the limbs, thus resulting in a significantly reduced quality of life. The currently available treatments primarily revolve around symptom management, and is thus palliative rather than curative. The aim of the present review is to briefly discuss the limitations of some of the currently available treatments for patients with OA, and highlight the value of the potential use of stem cells in cellular therapy, which is widely regarded as the breakthrough that can address the present unmet medical needs for treatment of degenerative diseases, such as OA. The advantages of stem cell therapy, particularly mesenchymal stem cells, and the challenges involved are also discussed in this review.

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August-2021
Volume 15 Issue 2

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Spandidos Publications style
Loo SJ and Loo SJ: Advantages and challenges of stem cell therapy for osteoarthritis (Review). Biomed Rep 15: 67, 2021
APA
Loo, S.J., & Loo, S.J. (2021). Advantages and challenges of stem cell therapy for osteoarthritis (Review). Biomedical Reports, 15, 67. https://doi.org/10.3892/br.2021.1443
MLA
Loo, S. J., Wong, N. K."Advantages and challenges of stem cell therapy for osteoarthritis (Review)". Biomedical Reports 15.2 (2021): 67.
Chicago
Loo, S. J., Wong, N. K."Advantages and challenges of stem cell therapy for osteoarthritis (Review)". Biomedical Reports 15, no. 2 (2021): 67. https://doi.org/10.3892/br.2021.1443