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Article Open Access

Effect of the roselle (Hibiscus sabdariffa L.) calyces drink on the physiological parameters of healthy adult subjects

  • Authors:
    • Ajeng Diantini
    • Syamsul Rahmat
    • Annisa Alpiani
    • Sri Adi Sumiwi
    • Leonardo Lubis
    • Jutti Levita
  • View Affiliations / Copyright

    Affiliations: Department of Pharmacology and Clinical Pharmacy, Faculty of Pharmacy, Universitas Padjadjaran, Bandung, West Java 45363, Indonesia, Department of Anatomy, Physiology, and Cell Biology, Faculty of Medicine, Universitas Padjadjaran, Bandung, West Java 45363, Indonesia
    Copyright: © Diantini et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Article Number: 89
    |
    Published online on: August 26, 2021
       https://doi.org/10.3892/br.2021.1465
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Abstract

The calyx of roselle (Hibiscus sabdariffa L.) has been the focus of attention of several studies, and although earlier studies on this plant showed it to possess antilipidemic and antidiabetic activities, none of these studies have assessed the effects of this plant on the physiological parameters of healthy subjects. The present study determined the effects of roselle calyx beverages on blood pressure, abdominal circumference, body mass index (BMI), hematological and urinary parameters, and the lipid profile of healthy subjects. Healthy subjects (n=30) were treated with a 200 ml roselle calyx beverage each morning and evening for 30 consecutive days. Every week the subjects were asked to perform some physical activity by following the Young Men's Christian Association step test. This study used a pre‑post quasi‑experimental design. Blood samples were taken before (day‑0) and after the intervention (day‑30). There was an increase in the levels of high‑density lipoproteins (from 47.0 to 49.5 mg/dl; P=0.015), and a significant decrease in both systolic and diastolic (P=0.036 and P=0.030, respectively), and the abdominal circumference of the subjects (P=0.005). However, total cholesterol levels (191.2 to 191.9 mg/dl; P=0.821) and low‑density lipoprotein levels (129.8 to 133.5 mg/dl; P=0.249) were slightly increased, although not significantly. A lower level of triglycerides (114.3 to 107.4 mg/dl; P=0.269) and very‑low‑density lipoprotein levels (22.8 to 21.4 mg/dl; P=0.681) was observed. No significant differences were detected in the BMI or the urinalysis parameters were identified. Based on these results, roselle (Hibiscus sabdariffa L.) may be used as a supplement to prospectively improve the health status of subjects. No serious adverse effects were observed during this trial.
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1 

Susilawati Y, Rahmatullah TS, Muhtadi A, Sofyan FF and Tjitraresmi A: Aktivitas antihipertensi ekstrak kering terstandarisasi kelopak bunga rosela (Hibiscus sabdariffa L.) hasil produksi skala pilot. J Sains Kes. 1:554–560. 2018.

2 

Abubakar SM, Ukeyima MT, Spencer JPE and Lovegrove JA: Acute effects of Hibiscus sabdariffa calyces on postprandial blood pressure, vascular function, blood lipids, biomarkers of insulin resistance and inflammation in humans. Nutrients. 11(341)2019.PubMed/NCBI View Article : Google Scholar

3 

McKay DL, Chen CY, Saltzman E and Blumberg JB: Hibiscus sabdariffa L. tea (tisane) lowers blood pressure in prehypertensive and mildly hypertensive adults. J Nutr. 140:298–303. 2010.PubMed/NCBI View Article : Google Scholar

4 

Herrera-Arellano A, Miranda-Sánchez J, Avila-Castro P, Herrera-Alvarez S, Jiménez-Ferrer JE, Zamilpa A, Román-Ramos R, Ponce-Monter H and Tortoriello J: Clinical effects produced by a standardized herbal medicinal product of Hibiscus sabdariffa on patients with hypertension. A randomized, double-blind, lisinopril-controlled clinical trial. Planta Med. 73:6–12. 2007.PubMed/NCBI View Article : Google Scholar

5 

Mozaffari-Khosravi H, Jalali-Khanabadi BA, Afkhami-Ardekani M, Fatehi F and Noori-Shadkam M: The effects of sour tea (Hibiscus sabdariffa) on hypertension in patients with type II diabetes. J Hum Hypertens. 23:48–54. 2009.PubMed/NCBI View Article : Google Scholar

6 

Tazoho G, Gouado I, Ndomou M, Bonsi S, Wamba Y and Agbor E: Clinical, hematological and biochemical health benefit effects of Hibiscus sabdariffa Lin dried calyces beverage in human. Food Nutr Sci. 7:383–395. 2016.

7 

Salami SO and Afolaya AJ: Suitability of roselle-hibiscus sabdariffa L. as raw material for soft drink production. J Foof Quality. 2020(8864142)2020.

8 

Indonesian National Standard SNI 01-2891-1992. Uji Makanan dan Minuman. Badan Standardisasi Nasional (BSN), Jakarta, Indonesia.

9 

Giusti MM and Wrolstad RE: Characterization and measurement of anthocyanins by UV-Visible Spectroscopy. Current Protocols in Food Analytical Chemistry. F1.2.1.–F1.2.13. 2001.

10 

Beutner F, Ubrich R, Zachariae S, Engel C, Sandri M, Teren A and Gielen S: Validation of a brief step-test protocol for estimation of peak oxygen uptake. Eur J Prev Cardiol. 22:503–512. 2015.PubMed/NCBI View Article : Google Scholar

11 

Teren A, Zachariae S, Beutner F, Ubrich R, Sandri M, Engel C, Löffler M and Gielen S: Incremental value of veterans specific activity questionnaire and the YMCA-step test for the assessment of cardiorespiratory fitness in population-based studies. Eur J Prev Cardiol. 23:1221–1227. 2016.PubMed/NCBI View Article : Google Scholar

12 

Casadei K and Kiel J: Anthropometric Μeasurement. StatPearls Publishing, Treasure Island, FL, 2021.

13 

Black DR, Coster DC and Paige SR: Physiological health parameters among college students to promote chronic disease prevention and health promotion. Prev Med Rep. 7:64–73. 2017.PubMed/NCBI View Article : Google Scholar

14 

Mutakin M, Irawan RM, Ratnasari T, Saraswati PI, Salma SP, Iskartama MJ, Megantara S and Levita J: Urinary sodium/potassium ratio and the effect of diet salt to blood pressure. SAJ Pharma Pharmacol. 5(301)2018.

15 

Corder CJ, Rathi BM, Sharif S and Leslie SW: 24-Hour Urine Collection. StatPearls Publishing, Treasure Island, FL, 2021.

16 

Milani DAQ and Jialal I: Urinalysis. StatPearls Publishing, Treasure Island, FL, 2021.

17 

Wu HY, Yang KM and Chiang PY: Roselle anthocyanins: Antioxidant properties and stability to heat and pH. Molecules. 23(1357)2018.PubMed/NCBI View Article : Google Scholar

18 

Mgaya-Kilima B, Remberg SF, Chove BE and Wicklund T: Physiochemical and antioxidant properties of roselle-mango juice blends; effects of packaging material, storage temperature and time. Food Sci Nutr. 3:100–109. 2015.PubMed/NCBI View Article : Google Scholar

19 

Bamishaiye EI, Olayemi FF and Bamishaiye OM: Effects of boiling time on mineral and vitamin c content of three varieties of Hibiscus sabdriffa drink in Nigeria. World J Agric Sci. 7:62–67. 2011.

20 

Aina JO and Shodipe AA: Colour stability and vitamin C retention of roselle juice (Hibiscus sabdariffa L) in different packaging materials. Nutr Food Sci. 36:90–95. 2006.

21 

Amor BB and Allaf K: Impact of texturing using instant pressure drop treatment prior to solvent extraction of anthocyanins from Malaysian Roselle (Hibiscus sabdariffa). Food Chem. 115:820–825. 2009.

22 

Cisse M, Vaillant F, Kane A, Ndiaye O and Dornier M: Impact of the extraction procedure on the kinetics of anthocyanin and colour degradation of roselle extracts during storage. J Sci Food Agri. 92:1214–1221. 2012.PubMed/NCBI View Article : Google Scholar

23 

Reis JF, Monteiro VV, de Souza Gomes R, do Carmo MM, da Costa GV, Ribera PC and Monteiro MC: Action mechanism and cardiovascular effect of anthocyanins: A systematic review of animal and human studies. J Transl Med. 14(315)2016.PubMed/NCBI View Article : Google Scholar

24 

Byrne JA, Grieve DJ, Bendall JK, Li JM, Gove C, Lambeth JD, Cave AC and Shah AM: Contrasting roles of NADPH oxidase isoforms in pressure-overload versus angiotensin II-induced cardiac hypertrophy. Circ Res. 93:802–805. 2003.PubMed/NCBI View Article : Google Scholar

25 

Ariviani S, Fauza G and Pawestri C: Development of dark roselle (Hibiscus sabdariffa) as potentially antioxidant isotonic drinks and its capability to improve physical fitness. Agritech. 37:386–394. 2017.

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Copy and paste a formatted citation
Spandidos Publications style
Diantini A, Rahmat S, Alpiani A, Sumiwi SA, Lubis L and Levita J: Effect of the roselle (<em>Hibiscus sabdariffa</em> L.) calyces drink on the physiological parameters of healthy adult subjects. Biomed Rep 15: 89, 2021.
APA
Diantini, A., Rahmat, S., Alpiani, A., Sumiwi, S.A., Lubis, L., & Levita, J. (2021). Effect of the roselle (<em>Hibiscus sabdariffa</em> L.) calyces drink on the physiological parameters of healthy adult subjects. Biomedical Reports, 15, 89. https://doi.org/10.3892/br.2021.1465
MLA
Diantini, A., Rahmat, S., Alpiani, A., Sumiwi, S. A., Lubis, L., Levita, J."Effect of the roselle (<em>Hibiscus sabdariffa</em> L.) calyces drink on the physiological parameters of healthy adult subjects". Biomedical Reports 15.5 (2021): 89.
Chicago
Diantini, A., Rahmat, S., Alpiani, A., Sumiwi, S. A., Lubis, L., Levita, J."Effect of the roselle (<em>Hibiscus sabdariffa</em> L.) calyces drink on the physiological parameters of healthy adult subjects". Biomedical Reports 15, no. 5 (2021): 89. https://doi.org/10.3892/br.2021.1465
Copy and paste a formatted citation
x
Spandidos Publications style
Diantini A, Rahmat S, Alpiani A, Sumiwi SA, Lubis L and Levita J: Effect of the roselle (<em>Hibiscus sabdariffa</em> L.) calyces drink on the physiological parameters of healthy adult subjects. Biomed Rep 15: 89, 2021.
APA
Diantini, A., Rahmat, S., Alpiani, A., Sumiwi, S.A., Lubis, L., & Levita, J. (2021). Effect of the roselle (<em>Hibiscus sabdariffa</em> L.) calyces drink on the physiological parameters of healthy adult subjects. Biomedical Reports, 15, 89. https://doi.org/10.3892/br.2021.1465
MLA
Diantini, A., Rahmat, S., Alpiani, A., Sumiwi, S. A., Lubis, L., Levita, J."Effect of the roselle (<em>Hibiscus sabdariffa</em> L.) calyces drink on the physiological parameters of healthy adult subjects". Biomedical Reports 15.5 (2021): 89.
Chicago
Diantini, A., Rahmat, S., Alpiani, A., Sumiwi, S. A., Lubis, L., Levita, J."Effect of the roselle (<em>Hibiscus sabdariffa</em> L.) calyces drink on the physiological parameters of healthy adult subjects". Biomedical Reports 15, no. 5 (2021): 89. https://doi.org/10.3892/br.2021.1465
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