<em>Staphylococcus aureus</em> mediastinitis following a skin infection in a non‑immunocompromised patient: A case report

Mantzouranis,Konstantinos; Georgakopoulou,Vasiliki Epameinondas; Mermigkis,Dimitrios; Damaskos,Christos; Garmpis,Nikolaos; Papalexis,Petros; Gkoufa,Aikaterini; Drossos,Panagiotis; Chlapoutakis,Serafeim; Garmpi,Anna; Sklapani,Pagona; Trakas,Nikolaos; Tsiafaki,Xanthi

doi:10.3892/br.2021.1480

December-2021 Volume 15 Issue 6

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December-2021 Volume 15 Issue 6

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Case Report Open Access

Staphylococcus aureus mediastinitis following a skin infection in a non‑immunocompromised patient: A case report

Authors:
- Konstantinos Mantzouranis
- Vasiliki Epameinondas Georgakopoulou
- Dimitrios Mermigkis
- Christos Damaskos
- Nikolaos Garmpis
- Petros Papalexis
- Aikaterini Gkoufa
- Panagiotis Drossos
- Serafeim Chlapoutakis
- Anna Garmpi
- Pagona Sklapani
- Nikolaos Trakas
- Xanthi Tsiafaki
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Affiliations: 1st Pulmonology Department Sismanogleio Hospital, 15126 Athens, Greece, Pulmonology Department, Laiko General Hospital, Medical School, National and Kapodistrian University of Athens, 11527 Athens, Greece, Renal Transplantation Unit, Laiko General Hospital, Medical School, National and Kapodistrian University of Athens, 11527 Athens, Greece, N.S. Christeas Laboratory of Experimental Surgery and Surgical Research; Medical School, National and Kapodistrian University of Athens, 11527 Athens, Greece, First Department of Propedeutic Internal Medicine, Laiko General Hospital, Medical School, National and Kapodistrian University of Athens, 11527 Athens, Greece, First Department of Internal Medicine, Laiko General Hospital, Medical School, National and Kapodistrian University of Athens, 11527 Athens, Greece, Department of Biomedical Sciences, University of West Attica, 12243 Athens, Greece, Department of Thoracic Surgery, Agios Savvas Hospital, 11522 Athens, Greece, Department of Cytology, Mitera Hospital, 15123 Athens, Greece, Department of Biochemistry, Sismanogleio Hospital, 15126 Athens, Greece

Copyright: © Mantzouranis et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
Article Number: 104
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Published online on: October 21, 2021

https://doi.org/10.3892/br.2021.1480
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Abstract

Mediastinitis is a severe inflammation of the structures located in the mid‑chest cavity. Three main causes of infective mediastinitis are traditionally recognized: Deep infection of a sternal wound following cardiothoracic surgery, perforation of the esophagus, and the descending necrotizing mediastinitis as a result of odontogenic, pharyngeal or cervical infections. Mediastinitis, as a complication of skin infection with hematogenous spread is infrequent. Methicillin‑resistant Staphylococcus aureus (MRSA) is a gram‑positive bacteria, and is responsible for numerous severe infections. MRSA mediastinitis is a rare infection and is typically associated with complications of sternotomy and retropharyngeal abscesses. Here, the second known case of mediastinitis of a hematogenous origin in a non‑immunocompromised 41‑year‑old patient following primary skin infection, accompanied by sternal osteomyelitis, lung consolidation and pleural effusion is described; MRSA was the responsible pathogen. The clinical course was favorable after 6 weeks of antibiotics administration without drainage or surgical intervention.

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Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

Staphylococcus aureus mediastinitis following a skin infection in a non‑immunocompromised patient: A case report

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