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Review Open Access

Importance of gut microbiome regulation for the prevention and recovery process after SARS‑CoV‑2 respiratory viral infection (Review)

  • Authors:
    • Nuroh Najmi
    • Imam Megantara
    • Lovita Andriani
    • Hanna Goenawan
    • Ronny Lesmana
  • View Affiliations / Copyright

    Affiliations: Department of Oral Biology, Faculty of Dentistry, Universitas Padjadjaran, Bandung, West Java 45363, Indonesia, Division of Biological Activty Central Laboratory, Universitas Padjadjaran, Bandung, West Java 45363, Indonesia, Faculty of Animal Husbandry, Universitas Padjadjaran, Bandung, West Java 45363, Indonesia
    Copyright: © Najmi et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Article Number: 25
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    Published online on: February 14, 2022
       https://doi.org/10.3892/br.2022.1508
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Abstract

Infection with severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2) has been reported to affect organs other than the lungs, including the liver, brain, kidneys and intestine, and gastrointestinal symptoms, such as nausea, vomiting, diarrhea and abdominal discomfort, have also been reported. Thus, SARS‑CoV‑2 could potentially directly or indirectly regulate the gut microbiome profile and its homeostasis. The abundance of Coprobacillus, Clostridium ramosum and Clostridium are associated with the severity of COVID‑19, and Firmicutes, Bacteriodetes, Proteobacteria and Actinobacteria are also related to COVID‑19 infection. The four phyla are correlated with the severity of COVID‑19 infection in patients. The modulation of factors that control the physiological growth of the gut microbiome will determine the proportionate ratio of microbiome types (profile). Taken together, gut microbiome profile alterations in COVID‑19 patients may have a cross effect with the modulation of cytokine levels in COVID‑19 infection. With these findings, several factors that regulate gut microbiome homeostasis may support the degree of the clinical symptoms and hasten the recovery process after COVID‑19 infection.
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Copy and paste a formatted citation
Spandidos Publications style
Najmi N, Megantara I, Andriani L, Goenawan H and Lesmana R: Importance of gut microbiome regulation for the prevention and recovery process after SARS‑CoV‑2 respiratory viral infection (Review). Biomed Rep 16: 25, 2022.
APA
Najmi, N., Megantara, I., Andriani, L., Goenawan, H., & Lesmana, R. (2022). Importance of gut microbiome regulation for the prevention and recovery process after SARS‑CoV‑2 respiratory viral infection (Review). Biomedical Reports, 16, 25. https://doi.org/10.3892/br.2022.1508
MLA
Najmi, N., Megantara, I., Andriani, L., Goenawan, H., Lesmana, R."Importance of gut microbiome regulation for the prevention and recovery process after SARS‑CoV‑2 respiratory viral infection (Review)". Biomedical Reports 16.4 (2022): 25.
Chicago
Najmi, N., Megantara, I., Andriani, L., Goenawan, H., Lesmana, R."Importance of gut microbiome regulation for the prevention and recovery process after SARS‑CoV‑2 respiratory viral infection (Review)". Biomedical Reports 16, no. 4 (2022): 25. https://doi.org/10.3892/br.2022.1508
Copy and paste a formatted citation
x
Spandidos Publications style
Najmi N, Megantara I, Andriani L, Goenawan H and Lesmana R: Importance of gut microbiome regulation for the prevention and recovery process after SARS‑CoV‑2 respiratory viral infection (Review). Biomed Rep 16: 25, 2022.
APA
Najmi, N., Megantara, I., Andriani, L., Goenawan, H., & Lesmana, R. (2022). Importance of gut microbiome regulation for the prevention and recovery process after SARS‑CoV‑2 respiratory viral infection (Review). Biomedical Reports, 16, 25. https://doi.org/10.3892/br.2022.1508
MLA
Najmi, N., Megantara, I., Andriani, L., Goenawan, H., Lesmana, R."Importance of gut microbiome regulation for the prevention and recovery process after SARS‑CoV‑2 respiratory viral infection (Review)". Biomedical Reports 16.4 (2022): 25.
Chicago
Najmi, N., Megantara, I., Andriani, L., Goenawan, H., Lesmana, R."Importance of gut microbiome regulation for the prevention and recovery process after SARS‑CoV‑2 respiratory viral infection (Review)". Biomedical Reports 16, no. 4 (2022): 25. https://doi.org/10.3892/br.2022.1508
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