Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Oncology Letters
      • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Biomedical Reports
      • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • Information for Authors
    • Information for Reviewers
    • Information for Librarians
    • Information for Advertisers
    • Conferences
  • Language Editing
Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • For Authors
    • For Reviewers
    • For Librarians
    • For Advertisers
    • Conferences
  • Language Editing
Login Register Submit
  • This site uses cookies
  • You can change your cookie settings at any time by following the instructions in our Cookie Policy. To find out more, you may read our Privacy Policy.

    I agree
Search articles by DOI, keyword, author or affiliation
Search
Advanced Search
presentation
Biomedical Reports
Join Editorial Board Propose a Special Issue
Print ISSN: 2049-9434 Online ISSN: 2049-9442
Journal Cover
February-2023 Volume 18 Issue 2

Full Size Image

Sign up for eToc alerts
Recommend to Library

Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

Journal Cover
February-2023 Volume 18 Issue 2

Full Size Image

Sign up for eToc alerts
Recommend to Library

  • Article
  • Citations
    • Cite This Article
    • Download Citation
    • Create Citation Alert
    • Remove Citation Alert
    • Cited By
  • Similar Articles
    • Related Articles (in Spandidos Publications)
    • Similar Articles (Google Scholar)
    • Similar Articles (PubMed)
  • Download PDF
  • Download XML
  • View XML
Article

Analysis of pharmacological interventions among hospitalised patients with COVID‑19: A focus on severe cases

  • Authors:
    • Yasutaka Shinoda
    • Kengo Ohashi
    • Tomoko Matsuoka
    • Tomoaki Yoshimura
  • View Affiliations / Copyright

    Affiliations: Department of Pharmacy, Ogaki Municipal Hospital, Ogaki, Gifu 503‑8502, Japan
  • Article Number: 11
    |
    Published online on: December 6, 2022
       https://doi.org/10.3892/br.2022.1593
  • Expand metrics +
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Metrics: Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )
Cited By (CrossRef): 0 citations Loading Articles...

This article is mentioned in:



Abstract

Existing recommendations regarding pharmaceutical interventions for patients with coronavirus disease 2019 (COVID‑19) focus on outpatient, inpatient and post‑discharge care. However, there are no studies examining the actual activities of pharmacists in relation to hospitalised patients. The present study aimed to identify pharmacists' roles by analysing cases of pharmaceutical interventions, particularly for patients admitted to high‑care units. Pharmacological interventions were provided to patients with severe COVID‑19 or patients at high risk of severe disease in 2021. These pharmaceutical interventions were analysed and evaluated. Pharmacists also developed a COVID‑19 drug compatibility chart for use by care team members. In the present study, 54 patients were included, of which 33 were severe cases. A total of 28 patients (52%) received pharmacological interventions and 25 of them were severe cases. Out of 68 pharmacological interventions, interventions for antimicrobial agents were the most common (28 interventions), followed by nutrition and anti‑COVID‑19 drug‑related interventions. In addition, the need for interventions relating to drug compatibility was reduced by ~43% after the drug compatibility chart was implemented. In conclusion, pharmacists have a responsibility to improve the quality of pharmacotherapy for patients with COVID‑19. They should focus on creating specific pharmacotherapy tools for patients with COVID‑19 and supporting appropriate antimicrobial use for secondary bacterial infections.
View Figures

Figure 1

View References

1 

Chu DK, Akl EA, Duda S, Solo K, Yaacoub S and Schünemann HJ: COVID-19 Systematic Urgent Review Group Effort (SURGE) study authors. Physical distancing, face masks, and eye protection to prevent person-to-person transmission of SARS-CoV-2 and COVID-19: A systematic review and meta-analysis. Lancet. 395:1973–1987. 2020.PubMed/NCBI View Article : Google Scholar

2 

Mistretta FA, Luzzago S, Molendini LO, Ferro M, Dossena E, Mastrilli F, Musi G and de Cobelli O: A guide for oncologic patient management during COVID-19 pandemic: The initial experience of an Italian oncologic hub with exemplificative focus on Uro-oncologic patients. Cancers (Basel). 12(1513)2020.PubMed/NCBI View Article : Google Scholar

3 

Song Z, Hu Y, Ren Z, Wang G, Liu S, Zheng S, Yang L and Zhao R: Optimal management of the public and patients by pharmacists in the era of COVID-19: An evidence-based review and practical recommendations. Front Public Health. 9(758325)2022.PubMed/NCBI View Article : Google Scholar

4 

Li M, Razaki H, Mui V, Rao P and Brocavich S: The pivotal role of pharmacists during the 2019 coronavirus pandemic. J Am Pharm Assoc (2003). 60:e73–e75. 2020.PubMed/NCBI View Article : Google Scholar

5 

Nguy J, Hitchen SA, Hort AL, Huynh C and Rawlins MDM: The role of a Coronavirus disease 2019 pharmacist: An Australian perspective. Int J Clin Pharm. 42:1379–1384. 2020.PubMed/NCBI View Article : Google Scholar

6 

Song Z, Hu Y, Zheng S, Yang L and Zhao R: Hospital pharmacists' pharmaceutical care for hospitalized patients with COVID-19: Recommendations and guidance from clinical experience. Res Social Adm Pharm. 17:2027–2031. 2021.PubMed/NCBI View Article : Google Scholar

7 

Gillespie L, Khan RZ, Stillson JE, Bunch CM, Shariff FS, Speybroeck J, Grisoli A, Schmidt MW, Phyu H, Jablonski J, et al: Impact of a clinical pharmacist on ultrasound-guided venous thromboembolism screening in hospitalized COVID-19 patients: A pilot prospective study. J Pharm Health Care Sci. 7(19)2021.PubMed/NCBI View Article : Google Scholar

8 

Lat I, Paciullo C, Daley MJ, MacLaren R, Bolesta S, McCann J, Stollings JL, Gross K, Foos SA, Roberts RJ, et al: Position paper on critical care pharmacy services: 2020 Update. Crit Care Med. 48:e813–e834. 2020.PubMed/NCBI View Article : Google Scholar

9 

Kondo M, Tanaka C, Tagami T, Nagano M, Sugaya K, Tagui N, Kaneko J, Kudo S, Kuno M, Unemoto K and Takase H: Utility of a compatibility chart for continuous infusions in the intensive care unit. J Nippon Med Sch. 89:227–232. 2022.PubMed/NCBI View Article : Google Scholar

10 

Maison O, Tardy C, Cabelguenne D, Parat S, Ducastelle S, Piriou V, Lepape A and Lalande L: Drug incompatibilities in intravenous therapy: Evaluation and proposition of preventive tools in intensive care and hematology units. Eur J Clin Pharmacol. 75:179–187. 2019.PubMed/NCBI View Article : Google Scholar

11 

Oda Y, Shimada M, Shiraishi S and Kurai O: Treatment and outcome of COVID-19 patients in a specialized hospital during the third wave: Advance of age and increased mortality compared with the first/second waves. JA Clin Rep. 7(85)2021.PubMed/NCBI View Article : Google Scholar

12 

Klopotowska JE, Kuiper R, van Kan HJ, de Pont AC, Dijkgraaf MG, Lie-A-Huen L, Vroom MB and Smorenburg SM: On-ward participation of a hospital pharmacist in a Dutch intensive care unit reduces prescribing errors and related patient harm: An intervention study. Crit Care. 14(R174)2010.PubMed/NCBI View Article : Google Scholar

13 

Ahmed N, Khan M, Saleem W, Karobari MI, Mohamed RN, Heboyan A, Rabaan AA, Mutair AA, Alhumaid S, Alsadiq SA, et al: Evaluation of Bi-Lateral Co-Infections and antibiotic resistance rates among COVID-19 patients. Antibiotics (Basel). 11(276)2022.PubMed/NCBI View Article : Google Scholar

14 

Cai Z, Yang Y and Zhang J: Obesity is associated with severe disease and mortality in patients with coronavirus disease 2019 (COVID-19): A meta-analysis. BMC Public Health. 21(1505)2021.PubMed/NCBI View Article : Google Scholar

15 

Dadras O, SeyedAlinaghi S, Karimi A, Shamsabadi A, Qaderi K, Ramezani M, Mirghaderi SP, Mahdiabadi S, Vahedi F, Saeidi S, et al: COVID-19 mortality and its predictors in the elderly: A systematic review. Health Sci Rep. 5(e657)2022.PubMed/NCBI View Article : Google Scholar

16 

Guan WJ, Ni ZY, Hu Y, Liang WH, Ou CQ, He JX, Liu L, Shan H, Lei CL, Hui DSC, et al: Clinical characteristics of coronavirus disease 2019 in China. N Engl J Med. 382:1708–1720. 2020.PubMed/NCBI View Article : Google Scholar

17 

Langford BJ, So M, Raybardhan S, Leung V, Westwood D, MacFadden DR, Soucy JR and Daneman N: Bacterial co-infection and secondary infection in patients with COVID-19: A living rapid review and meta-analysis. Clin Microbiol Infect. 26:1622–1629. 2020.PubMed/NCBI View Article : Google Scholar

18 

Terada M, Ohtsu H, Saito S, Hayakawa K, Tsuzuki S, Asai Y, Matsunaga N, Kutsuna S, Sugiura W and Ohmagari N: Risk factors for severity on admission and the disease progression during hospitalisation in a large cohort of patients with COVID-19 in Japan. BMJ Open. 11(e047007)2021.PubMed/NCBI View Article : Google Scholar

Related Articles

  • Abstract
  • View
  • Download
  • Twitter
Copy and paste a formatted citation
Spandidos Publications style
Shinoda Y, Ohashi K, Matsuoka T and Yoshimura T: Analysis of pharmacological interventions among hospitalised patients with COVID‑19: A focus on severe cases. Biomed Rep 18: 11, 2023.
APA
Shinoda, Y., Ohashi, K., Matsuoka, T., & Yoshimura, T. (2023). Analysis of pharmacological interventions among hospitalised patients with COVID‑19: A focus on severe cases. Biomedical Reports, 18, 11. https://doi.org/10.3892/br.2022.1593
MLA
Shinoda, Y., Ohashi, K., Matsuoka, T., Yoshimura, T."Analysis of pharmacological interventions among hospitalised patients with COVID‑19: A focus on severe cases". Biomedical Reports 18.2 (2023): 11.
Chicago
Shinoda, Y., Ohashi, K., Matsuoka, T., Yoshimura, T."Analysis of pharmacological interventions among hospitalised patients with COVID‑19: A focus on severe cases". Biomedical Reports 18, no. 2 (2023): 11. https://doi.org/10.3892/br.2022.1593
Copy and paste a formatted citation
x
Spandidos Publications style
Shinoda Y, Ohashi K, Matsuoka T and Yoshimura T: Analysis of pharmacological interventions among hospitalised patients with COVID‑19: A focus on severe cases. Biomed Rep 18: 11, 2023.
APA
Shinoda, Y., Ohashi, K., Matsuoka, T., & Yoshimura, T. (2023). Analysis of pharmacological interventions among hospitalised patients with COVID‑19: A focus on severe cases. Biomedical Reports, 18, 11. https://doi.org/10.3892/br.2022.1593
MLA
Shinoda, Y., Ohashi, K., Matsuoka, T., Yoshimura, T."Analysis of pharmacological interventions among hospitalised patients with COVID‑19: A focus on severe cases". Biomedical Reports 18.2 (2023): 11.
Chicago
Shinoda, Y., Ohashi, K., Matsuoka, T., Yoshimura, T."Analysis of pharmacological interventions among hospitalised patients with COVID‑19: A focus on severe cases". Biomedical Reports 18, no. 2 (2023): 11. https://doi.org/10.3892/br.2022.1593
Follow us
  • Twitter
  • LinkedIn
  • Facebook
About
  • Spandidos Publications
  • Careers
  • Cookie Policy
  • Privacy Policy
How can we help?
  • Help
  • Live Chat
  • Contact
  • Email to our Support Team