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Antiviral agents and disinfectants for foot‑and‑mouth disease (Review)

  • Authors:
    • Takashi Onodera
    • Akikazu Sakudo
    • Katsuaki Sugiura
    • Makoto Haritani
    • Koichi Furusaki
    • Rikio Kirisawa
  • View Affiliations / Copyright

    Affiliations: Laboratory of Environmental Science for Sustainable Development, Department of Veterinary Medical Sciences, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Bunkyo‑ku, Tokyo 113‑8657, Japan, Department of Food Safety, Faculty of Veterinary Medicine, Okayama University of Science, Imabari, Ehime 794‑8555, Japan, Laboratory of Environmental Science for Sustainable Development, Department of Veterinary Medical Sciences, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Bunkyo‑ku, Tokyo 113‑8657, Japan, Mineral Activation Research Institute, Kumamoto 865-0023, Japan
    Copyright: © Onodera et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Article Number: 57
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    Published online on: July 18, 2023
       https://doi.org/10.3892/br.2023.1639
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Abstract

Fluorouracil, 5‑azacytidine, 6‑azauridine, ribavirin, favipiravir (T‑705) and its derivative (T‑1105) exhibit anti‑foot‑and‑mouth disease virus (FMDV) effects. In particular, T‑1105 exhibits promising results when administered to guinea pigs orally, and pigs in their feed. FMDV is excreted in the early stages of infection in aerosols and oral or nasal droplets from animals. T‑1105 along with the FMDV vaccine can be used to combat foot‑and‑mouth disease (FMD) epidemics. Several studies have shown that sodium hypochlorous solutions are widely used to inactivate viruses, including FMDV. However, these solutions must be stored under cool and dark conditions to maintain their virucidal effects. Interestingly, a study indicated that the virucidal activity of a calcium bicarbonate solution with a mesoscopic structure (CAC‑717) did not decrease after storage at room temperature for at least four years outside direct sunlight. Numerous lessons acquired from the 2010 FMD outbreak in Japan are relevant for the control of COVID‑19. However, the widespread use of chlorite can cause environmental issues. Chlorite can be combined with nitrogen to produce chloramine or N‑nitrosodimethylamine, which plays a role in carcinogenesis. Therefore, risk assessments should be conducted in aquatic environments. Moreover, there is a need to develop nonchlorine disinfectants that can be used during epidemics, including FMD. The approach of ‘One Health’ should be shared between the public health and veterinary fields to improve the management of viral outbreaks, including those due to FMD.
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1 

Sakamoto K, Ohashi S, Yamazoe R, Takahashi K and Furuta Y: FAO report of the European commission for the control of foot-and mouth disease, pp414-420, 2006. Available at: https://www.fao.org/ag/againfo/commissions/docs/research_group/pahpos/App64.pdf. Accessed October 11, 2022.

2 

Muroga N, Hayama Y, Yamamoto T, Kurogi A, Tsuda T and Tsutsui T: The 2010 foot-and-mouth disease epidemic in Japan. J Vet Med Sci. 74:399–404. 2012.PubMed/NCBI View Article : Google Scholar

3 

Pariente N, Sierra S, Lowenstein PR and Domingo E: Efficient virus extinction by combinations of a mutagen and antiviral inhibitors. J Virol. 75:9723–9730. 2001.PubMed/NCBI View Article : Google Scholar

4 

Golde WT, Pacheco JM, Duque H, Doel T, Penfold B, Ferman GS, Gregg DR and Rodriguez LL: Vaccination against foot-and-mouth disease virus confers complete clinical protection in 7 days and partial protection in 4 days: Use in emergency outbreak response. Vaccine. 23:5775–5782. 2005.PubMed/NCBI View Article : Google Scholar

5 

Rada B and Dragún M: Antiviral action and selectivity of 6-azauridine. Ann N Y Acad Sci. 284:410–417. 1977.PubMed/NCBI View Article : Google Scholar

6 

Goris N, De Palma A, Toussaint JF, Musch I, Neyts J and De Clercq K: 2'-C-methylcytidine as a potent and selective inhibitor of the replication of foot-and-mouth disease virus. Antiviral Res. 73:161–168. 2007.PubMed/NCBI View Article : Google Scholar

7 

Lefebvre DJ, De Vleeschauwer AR, Goris N, Kollanur D, Billiet A, Murao L, Neyts J and De Clercq K: Proof of concept for the inhibition of foot-and-mouth disease virus replication by the anti-viral drug 2'-C-methylcytidine in severe combined immunodeficient mice. Transbound Emerg Dis. 61:e89–e91. 2014.PubMed/NCBI View Article : Google Scholar

8 

Furuta Y, Takahashi K, Shiraki K, Sakamoto K, Smee DF, Barnard DL, Gowen BB, Julander JG and Morrey JD: T-705 (favipiravir) and related compounds: Novel broad-spectrum inhibitors of RNA viral infections. Antiviral Res. 82:95–102. 2009.PubMed/NCBI View Article : Google Scholar

9 

De Vleeschauwer AR, Lefebvre DJ, Willems T, Paul G, Billiet A, Murao LE, Neyts J, Goris N and De Clercq K: A refined guinea pig model of foot-and-mouth disease virus infection for assessing the efficacy of antiviral compounds. Transbound Emerg Dis. 63:e205–e212. 2016.PubMed/NCBI View Article : Google Scholar

10 

Chen SF, Perrella FW, Behrens DL and Papp LM: Inhibition of dihydroorotate dehydrogenase activity by brequinar sodium. Cancer Res. 52:3521–3527. 1992.PubMed/NCBI

11 

Li SF, Gong MJ, Sun YF, Shao JJ, Zhang YG and Chang HY: In vitro and in vivo antiviral activity of mizoribine against foot-and-mouth disease virus. Molecules. 24(1723)2019.PubMed/NCBI View Article : Google Scholar

12 

Li SF, Gong MJ, Shao JJ, Sun YF, Zhang YG and Chang HY: Antiviral activity of merimepodib against foot and mouth disease virus in vitro and in vivo. Mol Immunol. 114:226–232. 2019.PubMed/NCBI View Article : Google Scholar

13 

Lanford RE, Guerra B, Chavez D, Giavedoni L, Hodara VL, Brasky KM, Fosdick A, Frey CR, Zheng J, Wolfgang G, et al: GS-9620, an oral agonist of Toll-like receptor-7, induces prolonged suppression of hepatitis B virus in chronically infected chimpanzees. Gastroenterology. 144:1508–1517, 1517.e1-e10. 2013.PubMed/NCBI View Article : Google Scholar

14 

de Avila AI, Moreno E, Perales C and Domingo E: Favipiravir can evoke lethal mutagenesis and extinction of foot-and-mouth disease virus. Virus Res. 233:105–112. 2017.PubMed/NCBI View Article : Google Scholar

15 

Furuta Y, Gowen BB, Takahashi K, Shiraki K, Smee DF and Barnard DL: Favipiravir (T-705), a novel viral RNA polymerase inhibitor. Antiviral Res. 100:446–454. 2013.PubMed/NCBI View Article : Google Scholar

16 

Jin Z, Tucker K, Lin X, Kao CC, Shaw K, Tan H, Symons J, Behera I, Rajwanshi VK, Dyatkina N, et al: Biochemical evaluation of the inhibition properties of favipiravir and 2'-C-methyl-cytidine triphosphates against human and mouse norovirus RNA polymerases. Antimicrob Agents Chemother. 59:7504–7516. 2015.PubMed/NCBI View Article : Google Scholar

17 

Smither SJ, Eastaugh LS, Steward JA, Nelson M, Lenk RP and Lever MS: Post-exposure efficacy of oral T-705 (Favipiravir) against inhalational Ebola virus infection in a mouse model. Antiviral Res. 104:153–155. 2014.PubMed/NCBI View Article : Google Scholar

18 

Malik P, Jain S, Jain P, Kumawat J, Dwivedi J and Kishore D: A comprehensive update on the structure and synthesis of potential drug targets for combating the coronavirus pandemic caused by SARS-CoV-2. Arch Pharm (Weinheim). 355(e2100382)2022.PubMed/NCBI View Article : Google Scholar

19 

Takehisa T: FMD status and control strategy in Japan. https://www.maff.go.jp/j/syouan/douei/pdf/japan.pdf. Accessed October 11, 2022.

20 

Furuta Y, Takahashi K, Kuno-Maekawa M, Sangawa H, Uehara S, Kozaki K, Nomura N, Egawa H and Shiraki K: Mechanism of action of T-705 against influenza virus. Antimicrob Agents Chemother. 49:981–986. 2005.PubMed/NCBI View Article : Google Scholar

21 

Nishi T, Fukai K, Masujin K, Kawaguchi R, Ikezawa M, Yamada M, Nakajima N, Komeno T, Furuta Y, Sugihara H, et al: Administration of the antiviral agent T-1105 fully protects pigs from foot-and-mouth disease infection. Antiviral Res. 208(105425)2022.PubMed/NCBI View Article : Google Scholar

22 

Nikunjkumar P, Tamil Selvan RP and Bhanuprakash V: Ribavirin as a curative and prophylactic agent against foot and mouth disease virus infection in C57BL/6 suckling and adult mice model. Virusdisease. 32:737–747. 2021.PubMed/NCBI View Article : Google Scholar

23 

Choi JH, Jeong K, Kim SM, Ko MK, You SH, Lyoo YS, Kim B, Ku JM and Park JH: Synergistic effect of ribavirin and vaccine for protection during early infection stage of foot-and-mouth disease. J Vet Sci. 19:788–797. 2018.PubMed/NCBI View Article : Google Scholar

24 

Platt H: A study of the pathological changes produced in young mice by the virus of foot-and-mouth disease. J Pathol Bacteriol. 72:299–312. 1956.PubMed/NCBI View Article : Google Scholar

25 

Zhang G, Zhou F, Gu B, Ding C, Feng D, Xie F, Wang J, Zhang C, Cao Q, Deng Y, et al: In vitro and in vivo evaluation of ribavirin and pleconaril antiviral activity against enterovirus 71 infection. Arch Virol. 157:669–679. 2012.PubMed/NCBI View Article : Google Scholar

26 

Qing M, Zou G, Wang QY, Xu HY, Dong H, Yuan Z and Shi PY: Characterization of dengue virus resistance to brequinar in cell culture. Antimicrob Agents Chemother. 54:3686–3695. 2010.PubMed/NCBI View Article : Google Scholar

27 

Luthra P, Naidoo J, Pietzsch CA, De S, Khadka S, Anantpadma M, Williams CG, Edwards MR, Davey RA, Bukreyev A, et al: Inhibiting pyrimidine biosynthesis impairs Ebola virus replication through depletion of nucleoside pools and activation of innate immune responses. Antiviral Res. 158:288–302. 2018.PubMed/NCBI View Article : Google Scholar

28 

Wang Y, Wang W, Xu L, Zhou X, Shokrollahi E, Felczak K, van der Laan LJ, Pankiewicz KW, Sprengers D, Raat NJ, et al: Cross talk between nucleotide synthesis pathways with cellular immunity in constraining hepatitis E virus replication. Antimicrob Agents Chemother. 60:2834–2848. 2016.PubMed/NCBI View Article : Google Scholar

29 

Li SF, Gong MJ, Sun YF, Shao JJ, Zhang YG and Chang HY: Antiviral activity of brequinar against foot-and-mouth disease virus infection in vitro and in vivo. Biomed Pharmacother. 116(108982)2019.PubMed/NCBI View Article : Google Scholar

30 

Ishikawa H: Mizoribine and mycophenolate mofetil. Curr Med Chem. 6:575–597. 1999.PubMed/NCBI

31 

Saijo M, Morikawa S, Fukushi S, Mizutani T, Hasegawa H, Nagata N, Iwata N and Kurane I: Inhibitory effect of mizoribine and ribavirin on the replication of severe acute respiratory syndrome (SARS)-associated coronavirus. Antiviral Res. 66:159–163. 2005.PubMed/NCBI View Article : Google Scholar

32 

Naka K, Ikeda M, Abe K, Dansako H and Kato N: Mizoribine inhibits hepatitis C virus RNA replication: Effect of combination with interferon-alpha. Biochem Biophys Res Commun. 330:871–879. 2005.PubMed/NCBI View Article : Google Scholar

33 

Jain J, Almquist SJ, Shlyakhter D and Harding MW: VX-497: A novel, selective IMPDH inhibitor and immunosuppressive agent. J Pharm Sci. 90:625–637. 2001.PubMed/NCBI View Article : Google Scholar

34 

Markland W, McQuaid TJ, Jain J and Kwong AD: Broad-spectrum antiviral activity of the IMP dehydrogenase inhibitor VX-497: A comparison with ribavirin and demonstration of antiviral additivity with alpha interferon. Antimicrob Agents Chemother. 44:859–866. 2000.PubMed/NCBI View Article : Google Scholar

35 

Decker CJ, Heiser AD, Chaturvedi PR, Faust TJ, Ku G, Moseley S and Nimmesgern E: The novel IMPDH inhibitor VX-497 prolongs skin graft survival and improves graft versus host disease in mice. Drugs Exp Clin Res. 27:89–95. 2001.PubMed/NCBI

36 

Fosdick A, Zheng J, Pflanz S, Frey CR, Hesselgesser J, Halcomb RL, Wolfgang G and Tumas DB: Pharmacokinetic and pharmacodynamic properties of GS-9620, a novel Toll-like receptor 7 agonist, demonstrate interferon-stimulated gene induction without detectable serum interferon at low oral doses. J Pharmacol Exp Ther. 348:96–105. 2014.PubMed/NCBI View Article : Google Scholar

37 

Bhagchandani S, Johnson JA and Irvine DJ: Evolution of Toll-like receptor 7/8 agonist therapeutics and their delivery approaches: From antiviral formulations to vaccine adjuvants. Adv Drug Deliv Rev. 175(113803)2021.PubMed/NCBI View Article : Google Scholar

38 

Lee G, Kang HR, Kim A, Park JH, Lee MJ and Kim SM: Antiviral effect of vesatolimod (GS-9620) against foot-and-mouth disease virus both in vitro and in vivo. Antiviral Res. 205(105384)2022.PubMed/NCBI View Article : Google Scholar

39 

Fukai K, Inoue K, Takeuchi A and Yamakawa M: New possibilities for egg white lysozyme: Heat-denatured lysozyme partially inactivates select foot-and-mouth disease virus strains. Sci Rep. 11(526)2021.PubMed/NCBI View Article : Google Scholar

40 

USDA. National Emergency Response to a Highly Contagious Animal Disease. Executive Summary, March 30, 2001. https://www.uvm.edu/sites/default/files/media/fmd_disinfectants.pdf?fbclid=IwAR3qbqvIPH2vVntcnsTrNb1PkA_ldovV5Vcyx95WMHM4PX2iw-dp-iTSCsM. Accessed October 15, 2022.

41 

Takahashi M, Takahashi H, Okakura Y, Ichikawa M, Kuda T and Kimura B: Impact of pH and protein hydrophobicity on norovirus inactivation by heat-denatured lysozyme. PLoS One. 15(e0237888)2020.PubMed/NCBI View Article : Google Scholar

42 

Harada Y, Lekcharoensuk P, Furuta T and Taniguchi T: Inactivation of foot-and-mouth disease virus by commercially available disinfectants and cleaners. Biocontrol Sci. 20:205–208. 2015.PubMed/NCBI View Article : Google Scholar

43 

Nakashima R, Kawamoto M, Miyazaki S, Onishi R, Furusaki K, Osaki M, Kirisawa R, Sakudo A and Onodera T: Evaluation of calcium hydrogen carbonate mesoscopic crystals as a disinfectant for influenza A viruses. J Vet Med Sci. 79:939–942. 2017.PubMed/NCBI View Article : Google Scholar

44 

Onodera T, Sakudo A, Iwamaru Y, Yokoyama T, Haritani M, Sugiura K, Shimakura H, Haga T, Onishi R and Furusaki K: Calcium bicarbonate as an antimicrobial, antiviral, and prion-inhibiting agent (review). Biomed Rep. 17(57)2022.PubMed/NCBI View Article : Google Scholar

45 

Kirisawa R, Kato R, Furusaki K and Onodera T: Universal virucidal activity of calcium bicarbonate mesoscopic crystals that provides an effective and biosafe disinfectant. Microorganisms. 10(262)2022.PubMed/NCBI View Article : Google Scholar

46 

Ishihara M, Murakami K, Fukuda K, Nakamura S, Kuwabara M, Hattori H, Fujita M, Kiyosawa T and Yokoe H: Stability of weakly acidic hypochlorous acid solution with microbicidal activity. Biocontrol Sci. 22:223–227. 2017.PubMed/NCBI View Article : Google Scholar

47 

Horiuchi I, Kawata H, Nagao T, Imaohji H, Murakami K, Kino Y, Yamasaki H, Koyama AH, Fujita Y, Goda H and Kuwahara T: Antimicrobial activity and stability of weakly acidified chlorous acid water. Biocontrol Sci. 20:43–51. 2015.PubMed/NCBI View Article : Google Scholar

48 

Sato Y, Ishihara M, Nakamura S, Fukuda K, Kuwabara M, Takayama T, Hiruma S, Murakami K, Fujita M and Yokoe H: Comparison of various disinfectants on bactericidal activity under organic matter contaminated environments. Biocontrol Sci. 24:103–108. 2019.PubMed/NCBI View Article : Google Scholar

49 

Goda H, Yamaoka H, Nakayama-Imaohji H, Kawata H, Horiuchi I, Fujita Y, Nagao T, Tada A, Terada A and Kuwahara T: Microbicidal effects of weakly acidified chlorous acid water against feline calicivirus and Clostridium difficile spores under protein-rich conditions. PLoS One. 12(e0176718)2017.PubMed/NCBI View Article : Google Scholar

50 

Hole K, Ahmadpour F, Krishnan J, Stansfield C, Copps J and Nfon C: Efficacy of accelerated hydrogen peroxide® disinfectant on foot-and-mouth disease virus, swine vesicular disease virus and Senecavirus A. J Appl Microbiol. 122:634–639. 2017.PubMed/NCBI View Article : Google Scholar

51 

Omidbakhsh N and Sattar SA: Broad-spectrum microbicidal activity, toxicologic assessment, and materials compatibility of a new generation of accelerated hydrogen peroxide-based environmental surface disinfectant. Am J Infect Control. 34:251–257. 2006.PubMed/NCBI View Article : Google Scholar

52 

Gabbert LR, Neilan JG and Rasmussen M: Recovery and chemical disinfection of foot-and-mouth disease and African swine fever viruses from porous concrete surfaces. J Appl Microbiol. 129:1092–1101. 2020.PubMed/NCBI View Article : Google Scholar

53 

Environmental Protection Agency (EPA). Antimicrobial testing methods and procedures: MB-05-14: AOAC use dilution method for testing disinfectants. https://www.epa.gov/sites/production/files/2016-08/documents/mb-05-14.pdf. Accessed December 9, 2019.

54 

Krug PW, Larson CR, Eslami AC and Rodriguez LL: Disinfection of foot-and-mouth disease and African swine fever viruses with citric acid and sodium hypochlorite on birch wood carriers. Vet Microbiol. 156:96–101. 2012.PubMed/NCBI View Article : Google Scholar

55 

EPA. List N advanced search page: Disinfectant for coronaviruses (COVID-19), 2021. https://www.epa.gov/pesticide-registration/list-n-advanced-search-page-disinfectants-coronavirus-covid-19. Accessed October 13, 2022.

56 

Chen B, Han J, Dai H and Jia P: Biocide-tolerance and antibiotic-resistance in community environments and risk of direct transfers to humans: Unintended consequences of community-wide surface disinfecting during COVID-19? Environ Pollut. 283(117074)2021.PubMed/NCBI View Article : Google Scholar

57 

Zhang H, Tang W, Chen Y and Yin W: Disinfection threatens aquatic ecosystems. Science. 368:146–147. 2020.PubMed/NCBI View Article : Google Scholar

58 

Bei E, Shu Y, Li S, Liao X, Wang J, Zhang X, Chen C and Krasner S: Occurrence of nitrosamines and their precursors in drinking water systems around mainland China. Water Res. 98:168–175. 2016.PubMed/NCBI View Article : Google Scholar

59 

Challis BC and Kyrtopoulos SA: Rapid formation of carcinogenic N-nitrosamines in aqueous alkaline solutions. Br J Cancer. 35:693–696. 1977.PubMed/NCBI View Article : Google Scholar

60 

World Health Organization (WHO), 2023: One Health, https://www.who.int/news-room/questions-and-answers/item/one-health, Accessed, 06 Jul 2023.

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Onodera T, Sakudo A, Sugiura K, Haritani M, Furusaki K and Kirisawa R: Antiviral agents and disinfectants for foot‑and‑mouth disease (Review). Biomed Rep 19: 57, 2023.
APA
Onodera, T., Sakudo, A., Sugiura, K., Haritani, M., Furusaki, K., & Kirisawa, R. (2023). Antiviral agents and disinfectants for foot‑and‑mouth disease (Review). Biomedical Reports, 19, 57. https://doi.org/10.3892/br.2023.1639
MLA
Onodera, T., Sakudo, A., Sugiura, K., Haritani, M., Furusaki, K., Kirisawa, R."Antiviral agents and disinfectants for foot‑and‑mouth disease (Review)". Biomedical Reports 19.3 (2023): 57.
Chicago
Onodera, T., Sakudo, A., Sugiura, K., Haritani, M., Furusaki, K., Kirisawa, R."Antiviral agents and disinfectants for foot‑and‑mouth disease (Review)". Biomedical Reports 19, no. 3 (2023): 57. https://doi.org/10.3892/br.2023.1639
Copy and paste a formatted citation
x
Spandidos Publications style
Onodera T, Sakudo A, Sugiura K, Haritani M, Furusaki K and Kirisawa R: Antiviral agents and disinfectants for foot‑and‑mouth disease (Review). Biomed Rep 19: 57, 2023.
APA
Onodera, T., Sakudo, A., Sugiura, K., Haritani, M., Furusaki, K., & Kirisawa, R. (2023). Antiviral agents and disinfectants for foot‑and‑mouth disease (Review). Biomedical Reports, 19, 57. https://doi.org/10.3892/br.2023.1639
MLA
Onodera, T., Sakudo, A., Sugiura, K., Haritani, M., Furusaki, K., Kirisawa, R."Antiviral agents and disinfectants for foot‑and‑mouth disease (Review)". Biomedical Reports 19.3 (2023): 57.
Chicago
Onodera, T., Sakudo, A., Sugiura, K., Haritani, M., Furusaki, K., Kirisawa, R."Antiviral agents and disinfectants for foot‑and‑mouth disease (Review)". Biomedical Reports 19, no. 3 (2023): 57. https://doi.org/10.3892/br.2023.1639
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