Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Oncology Letters
      • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Biomedical Reports
      • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • Information for Authors
    • Information for Reviewers
    • Information for Librarians
    • Information for Advertisers
    • Conferences
  • Language Editing
Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • For Authors
    • For Reviewers
    • For Librarians
    • For Advertisers
    • Conferences
  • Language Editing
Login Register Submit
  • This site uses cookies
  • You can change your cookie settings at any time by following the instructions in our Cookie Policy. To find out more, you may read our Privacy Policy.

    I agree
Search articles by DOI, keyword, author or affiliation
Search
Advanced Search
presentation
Biomedical Reports
Join Editorial Board Propose a Special Issue
Print ISSN: 2049-9434 Online ISSN: 2049-9442
Journal Cover
September-2023 Volume 19 Issue 3

Full Size Image

Sign up for eToc alerts
Recommend to Library

Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

Journal Cover
September-2023 Volume 19 Issue 3

Full Size Image

Sign up for eToc alerts
Recommend to Library

  • Article
  • Citations
    • Cite This Article
    • Download Citation
    • Create Citation Alert
    • Remove Citation Alert
    • Cited By
  • Similar Articles
    • Related Articles (in Spandidos Publications)
    • Similar Articles (Google Scholar)
    • Similar Articles (PubMed)
  • Download PDF
  • Download XML
  • View XML
Article Open Access

In vitro antioxidant and anticancer activities of Smilax corbularia extract combined with Phellinus linteus extract against breast cancer cell lines

  • Authors:
    • Alvi Jauharotus Syukriya
    • Wichanee Bankeeree
    • Sehanat Prasongsuk
    • Pattamawadee Yanatatsaneejit
  • View Affiliations / Copyright

    Affiliations: Program in Biotechnology, Faculty of Science, Chulalongkorn University, Bangkok 10330, Thailand, Plant and Biomass Utilization Research Unit, Department of Botany, Faculty of Science, Chulalongkorn University, Bangkok 10330, Thailand, Human Genetics Research Group and Plant Breeding Laboratory, Department of Botany, Faculty of Science, Chulalongkorn University, Bangkok 10330, Thailand
    Copyright: © Syukriya et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Article Number: 63
    |
    Published online on: August 7, 2023
       https://doi.org/10.3892/br.2023.1645
  • Expand metrics +
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Metrics: Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )
Cited By (CrossRef): 0 citations Loading Articles...

This article is mentioned in:



Abstract

Treatment with extracts from whole herbs has been reported to synergistically enhance the anticancer activities of therapeutic agents in recent studies. The present study evaluated the antioxidant and anticancer activities of Smilax corbularia Kunth (S. corbularia) and Phellinus linteus (P. linteus) crude extracts individually and in combination. S. corbularia was extracted using ethanol, whereas P. linteus was extracted using hot water. Both crude extracts underwent physiochemical characterization. Subsequently, the possible antioxidant activities of both crude extracts, individually and in combination, were evaluated using 2,2‑Diphenyl‑1‑picrylhydrazyl and 2,2'‑azino‑bis (3‑ethylbenzothiazoline‑6‑sulfonic acid) assays. Their effects on breast cancer cell cytotoxicity, proliferation and apoptosis were then assessed. The crude S. corbularia extract obtained was found to have a high level of total phenolic content, whilst the crude P. linteus extract had high levels of total polysaccharide content. The total phenolic content and total polysaccharide content results of the combinations depended on the respective ratios of the individual extracts. S. corbularia alone and combination 3 (which contained 75% S. corbularia: 25% P. linteus) demonstrated the greatest radical scavenging activity, followed by combination 1 (50% S. corbularia: 50% P. linteus), combination 2 (25% S. corbularia: 75% P. linteus) and P. linteus. The toxicity results of the extract samples on the cancer cells corresponded with their antioxidant activity. In particular, certain combinations demonstrated clearer inhibitory effects on cell proliferation against three types of breast cancer cells compared with those exerted by the two individual extracts. However, induction of apoptosis was limited, with the degree of apoptosis observed to be <5%. These findings suggested that treatment with combinations of these two extracts could confer enhanced antioxidant and antiproliferative effects on breast cancer cells. Therefore, the potential of these two extracts in combination as anticancer agents warrants further investigation.
View Figures

Figure 1

Figure 2

Figure 3

Figure 4

View References

1 

Khan AQ, Rashid K, AlAmodi AA, Agha MV, Akhtar S, Hakeem I, Raza SS and Uddin S: Reactive oxygen species (ROS) in cancer pathogenesis and therapy: An update on the role of ROS in anticancer action of benzophenanthridine alkaloids. Biomed Pharmacother. 143(112142)2021.PubMed/NCBI View Article : Google Scholar

2 

Tufail AB, Ma YK, Kaabar MKA, Martínez F, Junejo AR, Ullah I and Khan R: Deep learning in cancer diagnosis and prognosis prediction: A minireview on challenges, recent trends, and future directions. Comput Math Methods Med. 2021(9025470)2021.PubMed/NCBI View Article : Google Scholar

3 

Sung H, Ferlay J, Siegel RL, Laversanne M, Soerjomataram I, Jemal A and Bray F: Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 71:209–249. 2021.PubMed/NCBI View Article : Google Scholar

4 

Momenimovahed Z and Salehiniya H: Epidemiological characteristics of and risk factors for breast cancer in the world. Breast Cancer (Dove Med Press). 11:151–164. 2019.PubMed/NCBI View Article : Google Scholar

5 

Holliday DL and Speirs V: Choosing the right cell line for breast cancer research. Breast Cancer Res. 13(215)2011.PubMed/NCBI View Article : Google Scholar

6 

Bajalovic N, Or YZ, Woo ARE, Lee SH and Lin VCL: High levels of progesterone receptor B in MCF-7 cells enable radical anti-tumoral and anti-estrogenic effect of progestin. Biomedicines. 10(1860)2022.PubMed/NCBI View Article : Google Scholar

7 

Garcia E, Luna I, Persad KL, Agopsowicz K, Jay DA, West FG, Hitt MM and Persad S: Inhibition of triple negative breast cancer metastasis and invasiveness by novel drugs that target epithelial to mesenchymal transition. Sci Rep. 11(11757)2021.PubMed/NCBI View Article : Google Scholar

8 

Khattak MNK, Shanableh A, Hussain MI, Khan AA, Abdulwahab M, Radeef W and Samreen MH: Anticancer activities of selected Emirati Date (Phoenix dactylifera L.) varieties pits in human triple negative breast cancer MDA-MB-231 cells. Saudi J Biol Sci. 27:3390–3396. 2020.PubMed/NCBI View Article : Google Scholar

9 

Sarfraz A, Rasul A, Sarfraz I, Shah MA, Hussain G, Shafiq N, Masood M, Adem Ş, Sarker SD and Li X: Hispolon: A natural polyphenol and emerging cancer killer by multiple cellular signaling pathways. Environ Res. 190(110017)2020.PubMed/NCBI View Article : Google Scholar

10 

Lukong KE: Understanding breast cancer-The long and winding road. BBA Clin. 7:64–77. 2017.PubMed/NCBI View Article : Google Scholar

11 

Jeeno P, Tongban S, Yana P, Wongta A, Sutan K, Yadoung S and Hongsibsong S: Tentative identification of phytochemicals from smilax glabra and smilax corbularia extracts by LC-QTOF/MS and Their bioactive potential. Plants (Basel). 11(2089)2022.PubMed/NCBI View Article : Google Scholar

12 

She T, Qu L, Wang L, Yang X, Xu S, Feng J, Gao Y, Zhao C, Han Y, Cai S and Shou C: Sarsaparilla (Smilax Glabra Rhizome) extract inhibits cancer cell growth by S phase arrest, apoptosis, and autophagy via redox-dependent ERK1/2 pathway. Cancer Prev Res (Phila). 8:464–474. 2015.PubMed/NCBI View Article : Google Scholar

13 

Ruangnoo S, Jaiaree N, Makchuchit S, Panthong S, Thongdeeying P and Itharat A: An in vitro inhibitory effect on RAW 264.7 cells by anti-inflammatory compounds from Smilax corbularia Kunth. Asian Pac J Allergy Immunol. 30:268–274. 2012.PubMed/NCBI

14 

Qin D, Han S, Liu M, Guo T, Hu Z, Zhou Y and Luo F: Polysaccharides from Phellinus linteus: A systematic review of their extractions, purifications, structures and functions. Int J Biol Macromol. 230(123163)2023.PubMed/NCBI View Article : Google Scholar

15 

Yu K, Tan Z and Xin Y: Systematic evaluation of the anti-tumor effect of Phellinus linteus polysaccharide in thyroid carcinoma in vitro. Mol Biol Rep. 49:2785–2793. 2022.PubMed/NCBI View Article : Google Scholar

16 

He P, Zhang Y and Li N: The phytochemistry and pharmacology of medicinal fungi of the genus Phellinus: A review. Food Funct. 12:1856–1881. 2021.PubMed/NCBI View Article : Google Scholar

17 

Shin MR, Lee JH, Lee JA, Kim MJ, Park HJ, Park BW, Seo SB and Roh SS: Immunomodulatory and anti-inflammatory effects of Phellinus linteus mycelium. BMC Complement Med Ther. 21(269)2021.PubMed/NCBI View Article : Google Scholar

18 

Oh KK, Adnan M and Cho DH: Active ingredients and mechanisms of Phellinus linteus (grown on Rosa multiflora) for alleviation of type 2 diabetes mellitus through network pharmacology. Gene. 768(145320)2021.PubMed/NCBI View Article : Google Scholar

19 

Chen X, Li H, Zhang B and Deng Z: The synergistic and antagonistic antioxidant interactions of dietary phytochemical combinations. Crit Rev Food Sci Nutr. 62:5658–5677. 2022.PubMed/NCBI View Article : Google Scholar

20 

Habtemariam S: Going back to the good old days: The merit of crude plant drug mixtures in the 21st century. Int J Complement Alt Med. 6(00182)2017.

21 

Wu Z, Gao R, Li H, Wang Y, Luo Y, Zou J, Zhao B and Chen S: New insight into the joint significance of dietary jujube polysaccharides and 6-gingerol in antioxidant and antitumor activities. RSC Adv. 11:33219–33234. 2021.PubMed/NCBI View Article : Google Scholar

22 

Moldovan ML, Iurian S, Puscas C, Silaghi-Dumitrescu R, Hanganu D, Bogdan C, Vlase L, Oniga I and Benedec D: A Design of Experiments strategy to enhance the recovery of polyphenolic compounds from Vitis vinifera by-products through heat reflux extraction. Biomolecules. 9(529)2019.PubMed/NCBI View Article : Google Scholar

23 

Fauzantoro A, Muharam Y and Gozan M: Improvement of nicotine yield by ethanolic heat reflux extraction of Nicotiana tabacum var. Virginia origin of ponorogo. Int J Appl Eng Res. 12:13891–13897. 2017.

24 

Chu D, HUang Z and He F: Comparison between sulfuric acid-phenol and sulfuric acid-anthrone methods used for determination of polysaccharides in shoots of Aralia elata (Miq.) Seem. Agricultural Biotechnology. 7(4)2018.

25 

Hong Y, Wang Z, Barrow CJ, Dunshea FR and Suleria HAR: High-throughput screening and characterization of phenolic compounds in stone fruits waste by LC-ESI-QTOF-MS/MS and their potential antioxidant activities. Antioxidants (Basel). 10(234)2021.PubMed/NCBI View Article : Google Scholar

26 

Ramos-Andrés M, Aguilera-Torre B and García-Serna J: Hydrothermal production of high-molecular weight hemicellulose-pectin, free sugars and residual cellulose pulp from discarded carrots. J Clean Prod. 290(125179)2021.

27 

Wang Y, Meng X, Li B, Sun X and Zhang Q: Effect of ultrasonic-assisted extraction on antioxidant activity and molecular weight distribution of polysaccharides from Schisandra Chinensis (Turcz.) baill. In: Proceeding of the 2011 4th International Conference on Biomedical Engineering and Informatics (BMEI). BMEI. 3:1213–1217. 2011.

28 

Mariani F, Tammachote R, Kusuma IW, Chavasiri W, Punnapayak H and Prasongsuk S: Phenolic contents and antioxidant activities of leaf extracts from Elaeocarpus submonoceras Miq. Songklanakarin J Sci Technol. 43:531–536. 2021.

29 

Gaber NB, El-Dahy SI and Shalaby EA: Comparison of ABTS, DPPH, permanganate, and methylene blue assays for determining antioxidant potential of successive extracts from pomegranate and guava residues. Biomass Conv Bioref. 5:4011–4020. 2021.

30 

Zhang Y, Chen M, Tao Y, Chu B, Ma Y, Lu K and Sun H: Natural 8-C-ascorbyl-(−)-epigallocatechin as antidiabetic agent: α-glucosidase and PTP-1B signaling pathway dual regulators. Fitoterapia. 162(105263)2022.PubMed/NCBI View Article : Google Scholar

31 

Daddiouaissa D, Amid A, Kabbashi NA, Fuad FA, Elnour AM and Epandy MAKMS: Antiproliferative activity of ionic liquid-graviola fruit extract against human breast cancer (MCF-7) cell lines using flow cytometry techniques. J Ethnopharmacol. 236:466–473. 2019.PubMed/NCBI View Article : Google Scholar

32 

Haryanti S, Ratnawati G and Rahmawati N: Curcuma zanthorrhiza Extracts Induce G2/M cell cycle arrest and apoptosis in 4T1 and MCF-7 human breast cancer cells. Adv Health Sci Res. 22:415–419. 2020.

33 

Ge Q, Mao JW, Zhang AQ, Wang YJ and Sun Pl: Purification, chemical characterization, and antioxidant activity of a polysaccharide from the fruiting bodies of sanghuang mushroom (Phellinus baumii Pilát). Food Sci Biotechnol. 22:301–307. 2013.

34 

Pei JJ, Wang ZB, Ma HL and Yan JK: Structural features and antitumor activity of a novel polysaccharide from alkaline extract of Phellinus linteus mycelia. Carbohydr Polym. 115:472–477. 2015.PubMed/NCBI View Article : Google Scholar

35 

Wang ZB, Pei JJ, Ma HL, Cai PF and Yan JK: Effect of extraction media on preliminary characterizations and antioxidant activities of Phellinus linteus polysaccharides. Carbohydr Polym. 109:49–55. 2014.PubMed/NCBI View Article : Google Scholar

36 

Ghosh S, Khatua S, Dasgupta A and Acharya K: Crude polysaccharide from the milky mushroom, Calocybe indica, modulates innate immunity of macrophage cells by triggering MyD88-dependent TLR4/NF-κB pathway. J Pharm Pharmacol. 73:70–81. 2021.PubMed/NCBI View Article : Google Scholar

37 

Zhang QW, Lin LG and Ye WC: Techniques for extraction and isolation of natural products: A comprehensive review. Chin Med. 13(20)2018.PubMed/NCBI View Article : Google Scholar

38 

Phong HX, Viet NT, Quyen NTN, Van Thinh P, Trung NM and Ngan TTK: Phytochemical screening, total phenolic, flavonoid contents, and antioxidant activities of four spices commonly used in Vietnamese traditional medicine. Mater Today Proc. 56:A1–A5. 2022.

39 

Kozarski M, Klaus A, Niksic M, Jakovljevic D, Helsper JPFG and Van Griensven LJLD: Antioxidative and immunomodulating activities of polysaccharide extracts of the medicinal mushrooms Agaricus bisporus, Agaricus brasiliensis, Ganoderma lucidum and Phellinus linteus. Food Chem. 129:1667–1675. 2011.

40 

Kim GY, Lee JY, Lee JO, Ryu CH, Choi BT, Jeong YK, Lee KW, Jeong SC and Choi YH: Partial characterization and immunostimulatory effect of a novel polysaccharide–protein complex extracted from Phellinus linteus. Biosci Biotechnol Biochem. 70:1218–1226. 2006.PubMed/NCBI View Article : Google Scholar

41 

Yan JK, Wang YY, Ma HL and Wang ZB: Ultrasonic effects on the degradation kinetics, preliminary characterization and antioxidant activities of polysaccharides from Phellinus linteus mycelia. Ultrason Sonochem. 29:251–257. 2016.PubMed/NCBI View Article : Google Scholar

42 

Durgo K, Koncar M, Komes D, Belscak-Cvitanovic A, Franekic J, Jakopovich I, Jakopovich N and Jakopovich B: Cytotoxicity of blended versus single medicinal mushroom extracts on human cancer cell lines: Contribution of polyphenol and polysaccharide content. Int J Med Mushrooms. 15:435–448. 2013.PubMed/NCBI View Article : Google Scholar

43 

Ghasemi M, Turnbull T, Sebastian S and Kempson I: The MTT Assay: Utility, limitations, pitfalls, and interpretation in bulk and single-cell analysis. Int J Mol Sci. 22(12827)2021.PubMed/NCBI View Article : Google Scholar

44 

Luo M, Zhou L, Huang Z, Li B, Nice EC, Xu J and Huang C: Antioxidant therapy in cancer: Rationale and progress. Antioxidants (Basel). 11(1128)2022.PubMed/NCBI View Article : Google Scholar

45 

Bajor M, Zych AO, Graczyk-Jarzynka A, Muchowicz A, Firczuk M, Trzeciak L, Gaj P, Domagala A, Siernicka M, Zagozdzon A, et al: Targeting peroxiredoxin 1 impairs growth of breast cancer cells and potently sensitises these cells to prooxidant agents. Br J Cancer. 119:873–884. 2018.PubMed/NCBI View Article : Google Scholar

46 

Annisaa E, Sasikirana W, Ekawati N and Dini IRE: Correlation between antioxidant and cytotoxic activity of parijoto (Medinilla speciosa Blume) Fractions in 4T1 cell line. Indonesian Journal of Cancer Chemoprevention. 12:21–27. 2021.

47 

Sivapatham S and Selvaraj L: Currently available molecular analyses for personalized tumor therapy (Review). Biomed Rep. 17(95)2022.PubMed/NCBI View Article : Google Scholar

48 

Wungsintaweekul B, Umehara K, Miyase T and Noguchi H: Estrogenic and anti-estrogenic compounds from the Thai medicinal plant, Smilax corbularia (Smilacaceae). Phytochemistry. 72:495–502. 2011.PubMed/NCBI View Article : Google Scholar

49 

Machana S, Weerapreeyakul N, Barusrux S, Thumanu K and Tanthanuch W: Synergistic anticancer effect of the extracts from Polyalthia evecta caused apoptosis in human hepatoma (HepG2) cells. Asian Pac J Trop Biomed. 2:589–596. 2012.PubMed/NCBI View Article : Google Scholar

50 

Yang Y, Chen Y, Wu JH, Ren Y, Liu B, Zhang Y and Yu H: Targeting regulated cell death with plant natural compounds for cancer therapy: A revisited review of apoptosis, autophagy-dependent cell death, and necroptosis. Phytother Res. 37:1488–1525. 2023.PubMed/NCBI View Article : Google Scholar

51 

Su Z, Yang Z, Xu Y, Chen Y and Yu Q: Apoptosis, autophagy, necroptosis, and cancer metastasis. Mol Cancer. 14(48)2015.PubMed/NCBI View Article : Google Scholar

52 

Alqudah MAY, Al-Samman R, Azaizeh M and Alzoubi KH: Amlodipine inhibits proliferation, invasion, and colony formation of breast cancer cells. Biomed Rep. 6(50)2022.PubMed/NCBI View Article : Google Scholar

53 

Chalertpet K, Sangkheereeput T, Somjit P, Bankeeree W and Yanatatsaneejit P: Effect of Smilax spp. and Phellinus linteus combination on cytotoxicity and cell proliferation of breast cancer cells. BMC Complement Med Ther. 23(177)2023.PubMed/NCBI View Article : Google Scholar

Related Articles

  • Abstract
  • View
  • Download
  • Twitter
Copy and paste a formatted citation
Spandidos Publications style
Syukriya AJ, Bankeeree W, Prasongsuk S and Yanatatsaneejit P: <em>In vitro</em> antioxidant and anticancer activities of <em>Smilax corbularia</em> extract combined with <em>Phellinus linteus</em> extract against breast cancer cell lines. Biomed Rep 19: 63, 2023.
APA
Syukriya, A.J., Bankeeree, W., Prasongsuk, S., & Yanatatsaneejit, P. (2023). <em>In vitro</em> antioxidant and anticancer activities of <em>Smilax corbularia</em> extract combined with <em>Phellinus linteus</em> extract against breast cancer cell lines. Biomedical Reports, 19, 63. https://doi.org/10.3892/br.2023.1645
MLA
Syukriya, A. J., Bankeeree, W., Prasongsuk, S., Yanatatsaneejit, P."<em>In vitro</em> antioxidant and anticancer activities of <em>Smilax corbularia</em> extract combined with <em>Phellinus linteus</em> extract against breast cancer cell lines". Biomedical Reports 19.3 (2023): 63.
Chicago
Syukriya, A. J., Bankeeree, W., Prasongsuk, S., Yanatatsaneejit, P."<em>In vitro</em> antioxidant and anticancer activities of <em>Smilax corbularia</em> extract combined with <em>Phellinus linteus</em> extract against breast cancer cell lines". Biomedical Reports 19, no. 3 (2023): 63. https://doi.org/10.3892/br.2023.1645
Copy and paste a formatted citation
x
Spandidos Publications style
Syukriya AJ, Bankeeree W, Prasongsuk S and Yanatatsaneejit P: <em>In vitro</em> antioxidant and anticancer activities of <em>Smilax corbularia</em> extract combined with <em>Phellinus linteus</em> extract against breast cancer cell lines. Biomed Rep 19: 63, 2023.
APA
Syukriya, A.J., Bankeeree, W., Prasongsuk, S., & Yanatatsaneejit, P. (2023). <em>In vitro</em> antioxidant and anticancer activities of <em>Smilax corbularia</em> extract combined with <em>Phellinus linteus</em> extract against breast cancer cell lines. Biomedical Reports, 19, 63. https://doi.org/10.3892/br.2023.1645
MLA
Syukriya, A. J., Bankeeree, W., Prasongsuk, S., Yanatatsaneejit, P."<em>In vitro</em> antioxidant and anticancer activities of <em>Smilax corbularia</em> extract combined with <em>Phellinus linteus</em> extract against breast cancer cell lines". Biomedical Reports 19.3 (2023): 63.
Chicago
Syukriya, A. J., Bankeeree, W., Prasongsuk, S., Yanatatsaneejit, P."<em>In vitro</em> antioxidant and anticancer activities of <em>Smilax corbularia</em> extract combined with <em>Phellinus linteus</em> extract against breast cancer cell lines". Biomedical Reports 19, no. 3 (2023): 63. https://doi.org/10.3892/br.2023.1645
Follow us
  • Twitter
  • LinkedIn
  • Facebook
About
  • Spandidos Publications
  • Careers
  • Cookie Policy
  • Privacy Policy
How can we help?
  • Help
  • Live Chat
  • Contact
  • Email to our Support Team