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Article Open Access

Effect of intraoperative blood loss on postoperative complications and prognosis of patients with colorectal cancer: A meta‑analysis

  • Authors:
    • Zi-Wei Li
    • Xin-Peng Shu
    • Ze-Lin Wen
    • Fei Liu
    • Xu-Rui Liu
    • Quan Lv
    • Xiao-Yu Liu
    • Wei Zhang
    • Dong Peng
  • View Affiliations / Copyright

    Affiliations: Department of Gastrointestinal Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, P.R. China, Department of Gastrointestinal Surgery, Yongchuan Hospital of Chongqing Medical University, Chongqing 402160, P.R. China
    Copyright: © Li et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Article Number: 22
    |
    Published online on: December 14, 2023
       https://doi.org/10.3892/br.2023.1710
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Abstract

The purpose of the present study was to evaluate whether the amount of intraoperative blood loss (IBL) affects the complications and prognosis of patients with colorectal cancer (CRC). The PubMed, EMBASE and the Cochrane Library databases were used to search for eligible studies from inception to November 30, 2020. Hazard ratios (HRs) and 95% confidence intervals (Cls) were pooled up. The overall survival (OS) and disease‑free survival (DFS) were compared between the larger IBL group and the smaller IBL group. The present study was performed with RevMan 5.3 (The Cochrane Collaboration). A total of seven studies involving 1,540 patients with CRC were included in the present study. The smaller IBL group had a higher rate of OS (HR=1.45, 95% CI=1.17 to 1.8, P=0.0007) and a higher rate of DFS (HR=1.76, 95% CI=1.40 to 2.21, P<0.00001). Furthermore, the larger IBL group had a higher rate of postoperative complications than the smaller IBL group (odds ratio=2.06, 95% CI=1.72 to 2.15, P<0.00001). In conclusion, a smaller IBL was associated with better OS and DFS, and a lower risk of postoperative complications compared with a larger IBL in patients with CRC, suggesting that surgeons should pay more attention during perioperative management and surgical operation to reduce IBL.
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Copy and paste a formatted citation
Spandidos Publications style
Li Z, Shu X, Wen Z, Liu F, Liu X, Lv Q, Liu X, Zhang W and Peng D: Effect of intraoperative blood loss on postoperative complications and prognosis of patients with colorectal cancer: A meta‑analysis. Biomed Rep 20: 22, 2024.
APA
Li, Z., Shu, X., Wen, Z., Liu, F., Liu, X., Lv, Q. ... Peng, D. (2024). Effect of intraoperative blood loss on postoperative complications and prognosis of patients with colorectal cancer: A meta‑analysis. Biomedical Reports, 20, 22. https://doi.org/10.3892/br.2023.1710
MLA
Li, Z., Shu, X., Wen, Z., Liu, F., Liu, X., Lv, Q., Liu, X., Zhang, W., Peng, D."Effect of intraoperative blood loss on postoperative complications and prognosis of patients with colorectal cancer: A meta‑analysis". Biomedical Reports 20.2 (2024): 22.
Chicago
Li, Z., Shu, X., Wen, Z., Liu, F., Liu, X., Lv, Q., Liu, X., Zhang, W., Peng, D."Effect of intraoperative blood loss on postoperative complications and prognosis of patients with colorectal cancer: A meta‑analysis". Biomedical Reports 20, no. 2 (2024): 22. https://doi.org/10.3892/br.2023.1710
Copy and paste a formatted citation
x
Spandidos Publications style
Li Z, Shu X, Wen Z, Liu F, Liu X, Lv Q, Liu X, Zhang W and Peng D: Effect of intraoperative blood loss on postoperative complications and prognosis of patients with colorectal cancer: A meta‑analysis. Biomed Rep 20: 22, 2024.
APA
Li, Z., Shu, X., Wen, Z., Liu, F., Liu, X., Lv, Q. ... Peng, D. (2024). Effect of intraoperative blood loss on postoperative complications and prognosis of patients with colorectal cancer: A meta‑analysis. Biomedical Reports, 20, 22. https://doi.org/10.3892/br.2023.1710
MLA
Li, Z., Shu, X., Wen, Z., Liu, F., Liu, X., Lv, Q., Liu, X., Zhang, W., Peng, D."Effect of intraoperative blood loss on postoperative complications and prognosis of patients with colorectal cancer: A meta‑analysis". Biomedical Reports 20.2 (2024): 22.
Chicago
Li, Z., Shu, X., Wen, Z., Liu, F., Liu, X., Lv, Q., Liu, X., Zhang, W., Peng, D."Effect of intraoperative blood loss on postoperative complications and prognosis of patients with colorectal cancer: A meta‑analysis". Biomedical Reports 20, no. 2 (2024): 22. https://doi.org/10.3892/br.2023.1710
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