Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Oncology Letters
      • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Biomedical Reports
      • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • Information for Authors
    • Information for Reviewers
    • Information for Librarians
    • Information for Advertisers
    • Conferences
  • Language Editing
Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • For Authors
    • For Reviewers
    • For Librarians
    • For Advertisers
    • Conferences
  • Language Editing
Login Register Submit
  • This site uses cookies
  • You can change your cookie settings at any time by following the instructions in our Cookie Policy. To find out more, you may read our Privacy Policy.

    I agree
Search articles by DOI, keyword, author or affiliation
Search
Advanced Search
presentation
Biomedical Reports
Join Editorial Board Propose a Special Issue
Print ISSN: 2049-9434 Online ISSN: 2049-9442
Journal Cover
March-2024 Volume 20 Issue 3

Full Size Image

Sign up for eToc alerts
Recommend to Library

Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

Journal Cover
March-2024 Volume 20 Issue 3

Full Size Image

Sign up for eToc alerts
Recommend to Library

  • Article
  • Citations
    • Cite This Article
    • Download Citation
    • Create Citation Alert
    • Remove Citation Alert
    • Cited By
  • Similar Articles
    • Related Articles (in Spandidos Publications)
    • Similar Articles (Google Scholar)
    • Similar Articles (PubMed)
  • Download PDF
  • Download XML
  • View XML
Review Open Access

Physalis angulata Linn. as a medicinal plant (Review)

  • Authors:
    • Ariyani Novitasari
    • Enny Rohmawaty
    • Aziiz M. Rosdianto
  • View Affiliations / Copyright

    Affiliations: Magister Program of Biomedical Sciences, Faculty of Medicine, Universitas Padjadjaran, Sumedang, West Java 45363, Indonesia, Division of Pharmacology and Therapy, Department of Biomedical Sciences, Faculty of Medicine, Universitas Padjadjaran, Sumedang, West Java 45363, Indonesia, Veterinary Medicine Program, Department of Biomedical Sciences, Faculty of Medicine, Universitas Padjadjaran, Sumedang, West Java 45363, Indonesia
    Copyright: © Novitasari et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Article Number: 47
    |
    Published online on: January 24, 2024
       https://doi.org/10.3892/br.2024.1735
  • Expand metrics +
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Metrics: Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )
Cited By (CrossRef): 0 citations Loading Articles...

This article is mentioned in:



Abstract

There are numerous medicinal benefits from herbal plants, with many herbal medicines being used as ‘Jamu’, ‘standardized herbal medicines’ and phytopharmaceuticals. Physalis angulata Linn. (P. angulata L.), a plant utilized for both medicinal and food consumption purposes in a number of tropical and subtropical nations, is widely studied for its beneficial properties. The present review summarized the scientific evidence which suggested that P. angulata L. possesses antibacterial, anticancer, antiparasitic, anti‑inflammatory, antifibrotic and antidiabetic properties. Furthermore, the various pharmacological studies that have been conducted utilizing in vivo and in vitro models, as well as the identification of phytochemical components with therapeutic value are described. In addition, the present review explained the solvents and the toxicity tests that were used for the investigation of P. angulata L. The authors aspire that this literature review will provide an overview for researchers regarding the scientific progress of P. angulata L. over the past ten years and the potential areas of future research.
View Figures

Figure 1

Figure 2

Figure 3

Figure 4

Figure 5

View References

1 

Kasali FM, Tusiimire J, Kadima JN, Tolo CU, Weisheit A and Agaba AG: Ethnotherapeutic uses and phytochemical composition of Physalis peruviana L.: An overview. ScientificWorldJournal. 2021(5212348)2021.PubMed/NCBI View Article : Google Scholar

2 

Mahklouf MH: The first record of Physalis angulata L. (Solanaceae) for the flora of Libya. Biodiv Res Conserv. 53:67–71. 2019.

3 

Ramakrishna Pillai J, Wali AF, Menezes GA, Rehman MU, Wani TA, Arafah A, Zargar S and Mir TM: Chemical composition analysis, cytotoxic, antimicrobial and antioxidant activities of Physalis angulata L.: A comparative study of leaves and fruit. Molecules. 27(1480)2022.PubMed/NCBI View Article : Google Scholar

4 

Gao CY, Ma T, Luo J and Kong LY: Three new cytotoxic withanolides from the Chinese folk medicine Physalis angulata. Nat Prod Commun. 10:2059–2062. 2015.PubMed/NCBI

5 

Hadiyanti N, Supriyadi S and Pardono P: Keragaman beberapa tumbuhan ciplukan (Physalis spp.) di lereng gunung kelud, jawa timur. Berita Biologi. 17:135–146. 2018.

6 

Fadhli H, Ruska Sl, Furi M, Suhery WN, Susanti E and Nasution MR: Ciplukan (Physalis angulata L.): Review tanaman liar yang berpotensi sebagai tanaman obat. J Farm Indones. 15:134–141. 2023.

7 

Rivera DE, Ocampo YC, Castro JP, Caro D and Franco LA: Antibacterial activity of Physalis angulata L., Merremia umbellataL., and Cryptostegia grandiflora Roxb. Ex R.Br. -medicinal plants of the Colombian Northern Coast. Orient Pharm Exp Med. 15:95–102. 2015.

8 

Hananto H, Rahman A and Fahmi M: Antibacterial activity of ethanolic extract of morel berry (Physalis angulata L.) towards Staphylococcus aureus. Malays J Med Health Sci. 17:132–135. 2021.

9 

Gagare SB, Chavan SL and Sagade AB: Antibacterial potential and phytochemical screening of Physalis angulata and solanum virgianum. Int J Res Biosci Agric Technol. 1:36–40. 2021.

10 

Dias FGB, Ferreira MJG, da Silva LMR, de Sousa Menezes RC and de Figueiredo EAT: Bioaccessibility of the bioactive compounds and antimicrobial activity of aqueous extracts of Physalis angulata L. Rev Cienc Agron. 51(e20196619)2020.

11 

Cuong LCV, Dat TTH, Nhiem NX, Cuc NT, Yen DTH and Anh HLT: The anti-microbial activities of secosteroids isolated from Physalis angulata. Vietnam J Chem. 58:321–326. 2020.

12 

Anand U, Jacobo-Herrera N, Altemimi A and Lakhssassi N: A comprehensive review on medicinal plants as antimicrobial therapeutics: Potential avenues of biocompatible drug discovery. Metabolites. 9(258)2019.PubMed/NCBI View Article : Google Scholar

13 

Chairissy MD, Wulandari LR and Sujuti H: Pro-apoptotic and anti-proliferative effects of Physalis angulata leaf extract on retinoblastoma cells. Int J Ophthalmol. 12:1402–1407. 2019.PubMed/NCBI View Article : Google Scholar

14 

Yang Y, Yi L, Wang Q, Xie B, Sha C and Dong Y: Physalin B suppresses inflammatory response to lipopolysaccharide in RAW264.7 cells by inhibiting NF-κB signaling. J Chem. 4(7943140)2018.

15 

Guimarães ET, Lima MS, Santos LA, Ribeiro IM, Tomassini TBC, Ribeiro dos Santos R, dos Santos WLC and Soares MBP: Activity of physalins purified from Physalis angulata in in vitro and in vivo models of cutaneous leishmaniasis. J Antimicrob Chemother. 64:84–87. 2009.PubMed/NCBI View Article : Google Scholar

16 

Wang A, Wang S, Zhou F, Li P, Wang Y, Gan L and Lin L: Physalin B induces cell cycle arrest and triggers apoptosis in breast cancer cells through modulating p53-dependent apoptotic pathway. Biomed Pharmacother. 101:334–341. 2018.PubMed/NCBI View Article : Google Scholar

17 

Fang C, Chen C, Yang Y, Li K, Gao R, Xu D, Huang Y, Chen Z, Liu Z, Chen S, et al: Physalin B inhibits cell proliferation and induces apoptosis in undifferentiated human gastric cancer HGC-27 cells. Asia Pac J Clin Oncol. 18:224–231. 2022.PubMed/NCBI View Article : Google Scholar

18 

Magalhães HI, Veras ML, Torres MR, Alves AP, Pessoa OD, Silveira ER, Costa-Lotufo LV, de Moraes MO and Pessoa C: In-vitro and in-vivo antitumour activity of physalins B and D from Physalis angulata. J Pharm Pharmacol. 58:235–241. 2006.PubMed/NCBI View Article : Google Scholar

19 

Abdulridha MK, Al-Marzoqi AH, Al-Awsi GRL, Mubarak SMH, Heidarifard M and Ghasemian A: Anticancer Effects of herbal medicine compounds and novel formulations: A literature review. J Gastrointest Cancer. 51:765–773. 2020.PubMed/NCBI View Article : Google Scholar

20 

Meira CS, Guimarães ET, Bastos TM, Moreira DR, Tomassini TC, Ribeiro IM, Dos Santos RR and Soares MB: Physalins B and F, seco-steroids isolated from Physalis angulata L., strongly inhibit proliferation, ultrastructure and infectivity of Trypanosoma cruzi. Parasitology. 140:1811–1821. 2013.PubMed/NCBI View Article : Google Scholar

21 

Nogueira RC, Rocha VPC, Nonato FR, Tomassini TC, Ribeiro IM, dos Santos RR and Soares MB: Genotoxicity and antileishmanial activity evaluation of Physalis angulata concentrated ethanolic extract. Environ Toxicol Pharmacol. 36:1304–1311. 2013.PubMed/NCBI View Article : Google Scholar

22 

Sangshetti JN, Khan FAK, Kulkarni AA, Arote R and Patil RH: Antileishmanial drug discovery: Comprehensive review of the last 10 years. RSC Adv. 5:32376–32415. 2015.

23 

da Silva RR, da Silva BJ, Rodrigues AP, Farias LH, da Silva MN, Alves DT, Bastos GN, do Nascimento JL and Silva EO: In vitro biological action of aqueous extract from roots of Physalis angulata against Leishmania (Leishmania) amazonensis. BMC Complement Altern Med. 15(249)2015.

24 

Hassan AA, Khalid HE, Abdalla AH, Mukhtar MM, Osman WJ and Efferth T: Antileishmanial activities of medicinal herbs and phytochemicals in vitro and in vivo: An update for the years 2015 to 2021. Molecules. 27(7579)2022.PubMed/NCBI View Article : Google Scholar

25 

Ghasemian M, Owlia S and Owlia MB: Review of anti-inflammatory herbal medicines. Adv Pharmacol Sci. 2016(9130979)2016.PubMed/NCBI View Article : Google Scholar

26 

Yang YJ, Yi L, Wang Q, Xie BB, Dong Y and Sha CW: Anti-inflammatory effects of physalin E from Physalis angulata on lipopolysaccharide-stimulated RAW 264.7 cells through inhibition of NF-κB pathway. Immunopharmacol Immunotoxicol. 39:74–79. 2017.PubMed/NCBI View Article : Google Scholar

27 

Yen PH, Cuong LCV, Dat TTH, Thuy DTQ, Hoa DTN, Cuc NT, Yen DTH, Thao DT and Anh HLT: Withanolides from the whole plant of Physalis angulata and their anti-inflammatory activities. Vietnam J Chem. 57:334–338. 2019.

28 

Tuan Anh HL, Le Ba V, Do TT, Phan VK, Pham Thi HY, Bach LG, Tran MH, Tran Thi PA and Kim YH: Bioactive compounds from Physalis angulata and their anti-inflammatory and cytotoxic activities. J Asian Nat Prod Res. 23:809–817. 2021.PubMed/NCBI View Article : Google Scholar

29 

Wang L, Lu S, Wang L, Xin M, Xu Y, Wang G, Chen D, Chen L, Liu S and Zhao F: Anti-inflammatory effects of three withanolides isolated from Physalis angulata L. in LPS-activated RAW 264.7 cells through blocking NF-κB signaling pathway. J Ethnopharmacol. 276(114186)2021.PubMed/NCBI View Article : Google Scholar

30 

Ukwubile CA and Oise IE: Analgesic and anti-inflammatory activity of Physalis angulata Linn (Solanaceae) Leaf methanolic extract in swiss albino mice. Int Biol Biomed J Autumn. 2:167–70. 2016.

31 

Abdul-Nasir-Deen AY, Boakye YD, Osafo N, Agyare C, Boamah D, Boamah VE and Agyei EK: Anti-inflammatory and wound healing properties of methanol leaf extract of Physalis angulata L. S Afr J Bot. 133:124–131. 2020.

32 

do Espírito Santo RF, Lima MDS, Juiz PJL, Opretzka LCF, Nogueira RC, Ribeiro IM, Tomassini TCB, Soares MBP and Villarreal CF: Physalis angulata concentrated ethanolic extract suppresses nociception and inflammation by modulating cytokines and prostanoid pathways. Nat Prod Res. 35:4675–4679. 2021.PubMed/NCBI View Article : Google Scholar

33 

Almeida Junior LD, Quaglio AEV, de Almeida Costa CAR and Di Stasi LC: Intestinal anti-inflammatory activity of Ground Cherry (Physalis angulata L.) standardized CO2 phytopharmaceutical preparation. World J Gastroenterol. 23:4369–4380. 2017.PubMed/NCBI View Article : Google Scholar

34 

Arruda JCC, Rocha NC, Santos EG, Ferreira LGB, Bello ML, Penido C, Costa TEMM, Santos JAA, Ribeiro IM, Tomassini TCB and Faria RX: Physalin pool from Physalis angulata L. leaves and physalin D inhibit P2X7 receptor function in vitro and acute lung injury in vivo. Biomed Pharmacother. 142(112006)2021.PubMed/NCBI View Article : Google Scholar

35 

Wang B, Wu L, Chen J, Dong L, Chen C, Wen Z, Hu J, Fleming I and Wang DW: Metabolism pathways of arachidonic acids: Mechanisms and potential therapeutic targets. Signal Transduct Target Ther. 6(94)2021.PubMed/NCBI View Article : Google Scholar

36 

Rohmawaty E, Rosdianto AM, Usman HA, Saragih WAM, Zuhrotun A, Hendriani R, Wardhana YW, Ekawardhani S, Wiraswati HL, Agustanti N, et al: Antifibrotic effect of the ethyl acetate fraction of ciplukan (Physalis angulate Linn.) in rat liver fibrosis induced by CCI4. J Appl Pharm Sci. 11:175–182. 2021.

37 

Zhu X, Ye S, Yu D, Zhang Y, Li J, Zhang M, Leng Y, Yang T, Luo J, Chen X, et al: Physalin B attenuates liver fibrosis via suppressing LAP2α-HDAC1-mediated deacetylation of the transcription factor GLI1 and hepatic stellate cell activation. Br J Pharmacol. 178:3428–3437. 2021.PubMed/NCBI View Article : Google Scholar

38 

Dewi S, Isbagio H, Purwaningsih EH, Kertia N, Setiabudy R and Setiati S: A double-blind, randomized controlled trial of ciplukan (Physalis angulata Linn) extract on skin fibrosis, inflammatory, immunology, and fibrosis biomarkers in scleroderma patients. Acta Med Indones. 51:303–310. 2019.PubMed/NCBI

39 

Zhao M, Wang L, Wang M, Zhou S, Lu Y, Cui H, Racanelli AC, Zhang L, Ye T, Ding B, et al: Targeting fibrosis, mechanisms and cilinical trials. Signal Transduct Target Ther. 7(206)2022.PubMed/NCBI View Article : Google Scholar

40 

Raju P and Estari M: Anti-diabetic activity of compound isolated from Physalis angulata fruit extracts in alloxan-induced diabetic rats. Am J Sci Med Res. 1:40–43. 2015.

41 

Reddy PA, Vijay KR, Reddy GV, Reddy MK and Reddy YN: Anti-diabetic and hypolipidemic effect of aqueous and methanolic root extracts of Physalis angulata in streptozotocin (STZ) induced diabetic rats. Int J Pharm Res Scholars. 3:402–409. 2014.

42 

Kibiti CM and Afolayan AJ: Herbal therapy: A review of emerging pharmacological tools in the management of diabetes mellitus in Africa. Pharmacogn Mag. 11 (Suppl 2):S258–S274. 2015.PubMed/NCBI View Article : Google Scholar

43 

Daltro SRT, Santos IP, Barros PL, Moreira DRM, Tomassini TCB, Ribeiro IM, Ribeiro Dos Santos R, Meira CS and Soares MBP: In vitro and in vivo immunomodulatory activity of Physalis angulata concentrated ethanolic extract. Planta Med. 87:160–168. 2021.PubMed/NCBI View Article : Google Scholar

44 

Azwanida NN: A review on the extraction methods use in medicinal plants, principle, strength, and limitation. Med Aromat Plants. 4:1–6. 2015.

45 

Sulaiman SF, Sajak AAB, Ooi KL, Supriatno   and Seow EM: Effect of solvents in extracting polyphenols and antioxidants of selected raw vegetables. J Food Compos Anal. 24:506–515. 2011.

46 

Abubakar AR and Haque M: Preparation of medicinal plants: Basic extraction and fractionation procedures for experimental purposes. J Pharm Bioallied Sci. 12:1–10. 2020.PubMed/NCBI View Article : Google Scholar

47 

Pandey A and Tripathi S: Concept of standardization, extraction and pre-phytochemical screening strategies for herbal drug. J Pharmacogn Phytochem. 2:115–119. 2014.

48 

Sasidharan S, Chen Y, Saravanan D, Sundram KM and Yoga Latha L: Extraction, isolation and characterization of bioactive compounds from plants' extracts. Afr J Tradit Complement Altern Med. 8:1–10. 2011.PubMed/NCBI

49 

Altemimi A, Lakhssassi N, Baharlouei A, Watson DG and Lightfoot DA: Phytochemicals: Extraction, isolation, and identification of bioactive compounds from plant extracts. Plants (Basel). 6(42)2017.PubMed/NCBI View Article : Google Scholar

50 

Das K, Tiwari RKS and Shrivastava DK: Techniques for evaluation of medicinal plant products as antimicrobial agent: Current methods and future trends. J Med Plants Res. 4:104–111. 2010.

51 

Sukandar EY and Sheba SH: Acute and Sub-chronic toxicity studies of combination of Physalis angulata L. (Cecendet) extract and methylprednisolone on animals. Int J Integr Health Sci. 7:48–55. 2019.

52 

Rathore C, Dutt KR, Sahu S and Deb L: Antiasthmatic activity of the methanolic extract of Physalis angulate Linn. J Med Plants Res. 5:5351–5355. 2011.

53 

Pereda MDCV, Dieamant G, Nogueira C, Eberlin S, Facchini G, Mussi L, Polezel MA, Martins-Oliveira D, Rosa PTV and Di Stasi LC: Sterol-standardized phytopharmaceutical from ground cherry: Corticoid-like properties on human keratinocytes and fibroblasts and its effects in a randomized double-blind placebo-controlled clinical trial. J Cosmet Dermatol. 18:1516–1528. 2019.PubMed/NCBI View Article : Google Scholar

54 

Vieceli PS, Juiz PJL, Lauria PSS, Couto RD, Tomassini TCB, Ribeiro IM, Soares MBP and Villarreal CF: Physalis angulata reduces the progression of chronic experimental periodontitis by immunomodulatory mechanisms. J Ethnopharmacol. 273(113986)2021.PubMed/NCBI View Article : Google Scholar

55 

Meira CS, Guimarães ET, Dos Santos JA, Moreira DR, Nogueira RC, Tomassini TC, Ribeiro IM, de Souza CV, Ribeiro Dos Santos R and Soares MB: In vitro and in vivo antiparasitic activity of Physalis angulata L. concentrated ethanolic extract against Trypanosoma cruzi. Phytomedicine. 22:969–974. 2015.PubMed/NCBI View Article : Google Scholar

56 

da Silva BJM, Rodrigues APD, Farias LHS, Hage AAP, Do Nascimento JL and Silva EO: Physalis angulata induces in vitro differentiation of murine bone marrow cells into macrophages. BMC Cell Biol. 15(37)2014.PubMed/NCBI View Article : Google Scholar

57 

Pinto NB, Morais TC, Carvalho KMB, Silva CR, Andrade GM, Brito GAC, Veras ML, Pessoa ODL, Rao VS and Santos FA: Topical anti-inflammatory potential of Physalin E from Physalis angulata on experimental dermatitis in mice. Phytomedicine. 17:740–743. 2010.PubMed/NCBI View Article : Google Scholar

Related Articles

  • Abstract
  • View
  • Download
  • Twitter
Copy and paste a formatted citation
Spandidos Publications style
Novitasari A, Rohmawaty E and Rosdianto AM: <em>Physalis angulata</em> Linn. as a medicinal plant (Review). Biomed Rep 20: 47, 2024.
APA
Novitasari, A., Rohmawaty, E., & Rosdianto, A.M. (2024). <em>Physalis angulata</em> Linn. as a medicinal plant (Review). Biomedical Reports, 20, 47. https://doi.org/10.3892/br.2024.1735
MLA
Novitasari, A., Rohmawaty, E., Rosdianto, A. M."<em>Physalis angulata</em> Linn. as a medicinal plant (Review)". Biomedical Reports 20.3 (2024): 47.
Chicago
Novitasari, A., Rohmawaty, E., Rosdianto, A. M."<em>Physalis angulata</em> Linn. as a medicinal plant (Review)". Biomedical Reports 20, no. 3 (2024): 47. https://doi.org/10.3892/br.2024.1735
Copy and paste a formatted citation
x
Spandidos Publications style
Novitasari A, Rohmawaty E and Rosdianto AM: <em>Physalis angulata</em> Linn. as a medicinal plant (Review). Biomed Rep 20: 47, 2024.
APA
Novitasari, A., Rohmawaty, E., & Rosdianto, A.M. (2024). <em>Physalis angulata</em> Linn. as a medicinal plant (Review). Biomedical Reports, 20, 47. https://doi.org/10.3892/br.2024.1735
MLA
Novitasari, A., Rohmawaty, E., Rosdianto, A. M."<em>Physalis angulata</em> Linn. as a medicinal plant (Review)". Biomedical Reports 20.3 (2024): 47.
Chicago
Novitasari, A., Rohmawaty, E., Rosdianto, A. M."<em>Physalis angulata</em> Linn. as a medicinal plant (Review)". Biomedical Reports 20, no. 3 (2024): 47. https://doi.org/10.3892/br.2024.1735
Follow us
  • Twitter
  • LinkedIn
  • Facebook
About
  • Spandidos Publications
  • Careers
  • Cookie Policy
  • Privacy Policy
How can we help?
  • Help
  • Live Chat
  • Contact
  • Email to our Support Team