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Interleukin‑18 binding protein: Biological properties and roles in human and animal immune regulation (Review)

  • Authors:
    • Fengxue Wang
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    Affiliations: College of Veterinary Medicine, Key Laboratory for Clinical Diagnosis and Treatment of Animal Disease at the Ministry of Agriculture, Inner Mongolia Agricultural University, Inner Mongolia Autonomous Region, Huhhot 010018, P.R. China
    Copyright: © Wang et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Article Number: 87
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    Published online on: April 9, 2024
       https://doi.org/10.3892/br.2024.1775
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Abstract

IL‑18 binding protein (IL‑18BP) is a natural regulatory molecule of the proinflammatory cytokine IL‑18. It can regulate activity of IL‑18 by high affinity binding. The present review aimed to highlight developments, characteristics and functions of IL‑18BP. IL‑18BP serves biological and anti‑pathological roles in treating disease. In humans, it modulates progression of a number of chronic diseases, such as adult‑onset Still's disease. The present review summarizes molecular structure, role of IL‑18BP in disease and interaction with other proteins in important pathological processes.
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Spandidos Publications style
Wang F: Interleukin‑18 binding protein: Biological properties and roles in human and animal immune regulation (Review). Biomed Rep 20: 87, 2024.
APA
Wang, F. (2024). Interleukin‑18 binding protein: Biological properties and roles in human and animal immune regulation (Review). Biomedical Reports, 20, 87. https://doi.org/10.3892/br.2024.1775
MLA
Wang, F."Interleukin‑18 binding protein: Biological properties and roles in human and animal immune regulation (Review)". Biomedical Reports 20.6 (2024): 87.
Chicago
Wang, F."Interleukin‑18 binding protein: Biological properties and roles in human and animal immune regulation (Review)". Biomedical Reports 20, no. 6 (2024): 87. https://doi.org/10.3892/br.2024.1775
Copy and paste a formatted citation
x
Spandidos Publications style
Wang F: Interleukin‑18 binding protein: Biological properties and roles in human and animal immune regulation (Review). Biomed Rep 20: 87, 2024.
APA
Wang, F. (2024). Interleukin‑18 binding protein: Biological properties and roles in human and animal immune regulation (Review). Biomedical Reports, 20, 87. https://doi.org/10.3892/br.2024.1775
MLA
Wang, F."Interleukin‑18 binding protein: Biological properties and roles in human and animal immune regulation (Review)". Biomedical Reports 20.6 (2024): 87.
Chicago
Wang, F."Interleukin‑18 binding protein: Biological properties and roles in human and animal immune regulation (Review)". Biomedical Reports 20, no. 6 (2024): 87. https://doi.org/10.3892/br.2024.1775
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