Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Oncology Letters
      • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Biomedical Reports
      • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • Information for Authors
    • Information for Reviewers
    • Information for Librarians
    • Information for Advertisers
    • Conferences
  • Language Editing
Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • For Authors
    • For Reviewers
    • For Librarians
    • For Advertisers
    • Conferences
  • Language Editing
Login Register Submit
  • This site uses cookies
  • You can change your cookie settings at any time by following the instructions in our Cookie Policy. To find out more, you may read our Privacy Policy.

    I agree
Search articles by DOI, keyword, author or affiliation
Search
Advanced Search
presentation
Biomedical Reports
Join Editorial Board Propose a Special Issue
Print ISSN: 2049-9434 Online ISSN: 2049-9442
Journal Cover
October-2024 Volume 21 Issue 4

Full Size Image

Sign up for eToc alerts
Recommend to Library

Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

Journal Cover
October-2024 Volume 21 Issue 4

Full Size Image

Sign up for eToc alerts
Recommend to Library

  • Article
  • Citations
    • Cite This Article
    • Download Citation
    • Create Citation Alert
    • Remove Citation Alert
    • Cited By
  • Similar Articles
    • Related Articles (in Spandidos Publications)
    • Similar Articles (Google Scholar)
    • Similar Articles (PubMed)
  • Download PDF
  • Download XML
  • View XML

  • Supplementary Files
    • Supplementary_Data.pdf
Article Open Access

Comprehensive breast cancer risk analysis with whole exome sequencing and the prevalence of BRCA1 and ABCG2 mutations and oncogenic HPV

  • Authors:
    • Sureewan Bumrungthai
    • Sureewan Duangjit
    • Supaporn Passorn
    • Sutida Pongpakdeesakul
    • Siriwoot Butsri
    • Somwang Janyakhantikul
  • View Affiliations / Copyright

    Affiliations: Division of Biopharmaceutical Sciences, Faculty of Pharmaceutical Sciences, Ubon Ratchathani University, Ubon Ratchathani 34190, Thailand, Division of Pharmaceutical Chemistry and Technology, Faculty of Pharmaceutical Sciences, Ubon Ratchathani University, Ubon Ratchathani 34190, Thailand, Division of Biotechnology, School of Agriculture and Natural resources, University of Phayao, Phayao 56000, Thailand
    Copyright: © Bumrungthai et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Article Number: 144
    |
    Published online on: August 7, 2024
       https://doi.org/10.3892/br.2024.1832
  • Expand metrics +
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Metrics: Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )
Cited By (CrossRef): 0 citations Loading Articles...

This article is mentioned in:



Abstract

Breast cancer is the most prevalent cancer and also the leading cause of cancer death in women worldwide. A comprehensive understanding of breast cancer risk factors and their incidences is useful information for breast cancer prevention and control planning. The present study aimed to provide information on single nucleotide polymorphisms (SNPs) and copy number variations (CNVs) in breast cancer, the allele frequency of two SNPs in breast cancer‑related genes BRCA1 DNA repair associated (BRCA1; rs799917) and ATP binding cassette subfamily G member 2 (ABCG2; rs2231142), and the prevalence of human papillomavirus (HPV) infections in a normal population living in Phayao Province, Northern Thailand. One breast cancer and 10 healthy samples were investigated by whole exome sequencing (WES) and compared for genetic variation. The WES data contained SNPs in genes previously implicated in breast cancer and provided data on CNVs. The allele frequencies for SNPs rs799917 and rs2231142 were also examined. The SNP genotype frequencies were 35.88% CC, 46.54% CT, and 17.58% TT for rs799917 and 33.20% CC, 46.88% CA, and 19.92% AA for rs2231142. A total of 825 human whole blood samples were examined for HPV infection by PCR, and the pooled DNA was tested for HPV infection using metagenomic sequencing. No HPV infections were detected among all 825 samples or the pooled blood samples. The incidence of breast cancer among the tested samples was estimated based on acceptable breast cancer risk factors and demographic data and was 1.47%. The present study provided data on SNPs and CNVs in breast cancer‑related genes. The associations between SNPs rs2231142 and rs799917 and breast cancer should be further investigated in a case‑control study since heterozygous and homozygous variants are more common. Based on the detection of HPV infection in the blood samples, HPV may not be associated with breast cancer, at least in the Northern Thai population.
View Figures

Figure 1

Figure 2

Figure 3

View References

1 

Sung H, Ferlay J, Siegel RL, Laversanne M, Soerjomataram I, Jemal A and Bray F: Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 71:209–249. 2021.PubMed/NCBI View Article : Google Scholar

2 

Xu Y, Gong M, Wang Y, Yang Y, Liu S and Zeng Q: Global trends and forecasts of breast cancer incidence and deaths. Sci Data. 10(334)2023.PubMed/NCBI View Article : Google Scholar

3 

Ferlay J, Ervik M, Lam F, Laversanne M, Colombet M, Mery L, Piñeros M, Znaor A, Soerjomataram I and Bray F: Global cancer observatory: Cancer today. Lyon, France: International Agency for Research on Cancer, 2024. Available from: https://gco.iarc.who.int/today, accessed (15 February 2024).

4 

Łukasiewicz S, Czeczelewski M, Forma A, Baj J, Sitarz R and Stanisławek A: Breast cancer-epidemiology, risk factors, classification, prognostic markers, and current treatment strategies-an updated review. Cancers (Basel). 13(4287)2021.PubMed/NCBI View Article : Google Scholar

5 

Youn HJ and Han W: A review of the epidemiology of breast cancer in Asia: Focus on risk factors. Asian Pac J Cancer Prev. 21:867–880. 2020.PubMed/NCBI View Article : Google Scholar

6 

Momenimovahed Z and Salehiniya H: Epidemiological characteristics of and risk factors for breast cancer in the world. Breast Cancer (Dove Med Press). 11:151–164. 2019.PubMed/NCBI View Article : Google Scholar

7 

Takaoka M and Miki Y: BRCA1 gene: Function and deficiency. Int J Clin Oncol. 23:36–44. 2018.PubMed/NCBI View Article : Google Scholar

8 

Qin TT, Chen T, Zhang Q, Du HN, Shu YQ, Luo K and Zhu LJ: Association between BRCA1 rs799917 polymorphism and breast cancer risk: A meta-analysis of 19,878 subjects. Biomed Pharmacother. 68:905–910. 2014.PubMed/NCBI View Article : Google Scholar

9 

Yang M, Du X, Zhang F and Yuan S: Association between BRCA1 polymorphisms rs799917 and rs1799966 and breast cancer risk: A meta-analysis. J Int Med Res. 47:1409–1416. 2019.PubMed/NCBI View Article : Google Scholar

10 

Zhao H and Kong Z: Lack of association of BRCA1 gene rs799917 polymorphism with cancer risk. Int J Clin Exp Med. 10:15886–15895. 2017.

11 

Xu GP, Zhao Q, Wang D, Xie WY, Zhang LJ, Zhou H, Chen SZ and Wu LF: The association between BRCA1 gene polymorphism and cancer risk: A meta-analysis. Oncotarget. 9:8681–8694. 2018.PubMed/NCBI View Article : Google Scholar

12 

Wu H, Liu Y, Kang H, Xiao Q, Yao W, Zhao H, Wang E and Wei M: Genetic variations in ABCG2 gene predict breast carcinoma susceptibility and clinical outcomes after treatment with anthracycline-based chemotherapy. Biomed Res Int. 2015(279109)2015.PubMed/NCBI View Article : Google Scholar

13 

Ghafouri H, Ghaderi B, Amini S, Nikkhoo B, Abdi M and Hoseini A: Association of ABCB1 and ABCG2 single nucleotide polymorphisms with clinical findings and response to chemotherapy treatments in Kurdish patients with breast cancer. Tumour Biol. 37:7901–7906. 2016.PubMed/NCBI View Article : Google Scholar

14 

Al-Eitan LN, Rababa'h DM, Alghamdi MA and Khasawneh RH: Role of Four ABC transporter genes in pharmacogenetic susceptibility to breast cancer in Jordanian patients. J Oncol. 2019(6425708)2019.PubMed/NCBI View Article : Google Scholar

15 

Ren C, Zeng K, Wu C, Mu L, Huang J and Wang M: Human papillomavirus infection increases the risk of breast carcinoma: A large-scale systemic review and meta-analysis of case-control studies. Gland Surg. 8:486–500. 2019.PubMed/NCBI View Article : Google Scholar

16 

Graham R, Gazinska P, Zhang B, Khiabany A, Sinha S, Alaguthurai T, Flores-Borja F, Vicencio J, Beuron F, Roxanis I, et al: Serum-derived extracellular vesicles from breast cancer patients contribute to differential regulation of T-cell-mediated immune-escape mechanisms in breast cancer subtypes. Front Immunol. 14(1204224)2023.PubMed/NCBI View Article : Google Scholar

17 

Khodabandehlou N, Mostafaei S, Etemadi A, Ghasemi A, Payandeh M, Hadifar S, Norooznezhad AH, Kazemnejad A and Moghoofei M: Human papilloma virus and breast cancer: The role of inflammation and viral expressed proteins. BMC Cancer. 19(61)2019.PubMed/NCBI View Article : Google Scholar

18 

Kudela E, Kudelova E, Kozubík E, Rokos T, Pribulova T, Holubekova V and Biringer K: HPV-associated breast cancer: Myth or fact? Pathogens. 11(1510)2022.PubMed/NCBI View Article : Google Scholar

19 

Chen ACH, Keleher A, Kedda MA, Spurdle AB, McMillan NAJ and Antonsson A: Human papillomavirus DNA detected in peripheral blood samples from healthy Australian male blood donors. J Med Virol. 81:1792–1796. 2009.PubMed/NCBI View Article : Google Scholar

20 

Pongpakdeesakul S, Ekalaksananan T, Pientong C, Iamchuen N, Buddhisa S, Mahingsa K, Pingyod A, Sangsrijun W, Passorn S, Chopjitt P, et al: Human oncogenic epstein-barr virus in water and human blood infection of communities in Phayao Province, Thailand. Water. 15(323)2023.

21 

Sumala S, Ekalaksananan T, Pientong C, Buddhisa S, Passorn S, Duangjit S, Janyakhantikul S, Suktus A and Bumrungthai S: The association of HHV-6 and the TNF-α (-308G/A) promotor with major depressive disorder patients and healthy controls in Thailand. Viruses. 15(1898)2023.PubMed/NCBI View Article : Google Scholar

22 

Słomka M, Sobalska-Kwapis M, Wachulec M, Bartosz G and Strapagiel D: High resolution melting (HRM) for high-throughput genotyping-limitations and caveats in practical case studies. Int J Mol Sci. 18(2316)2017.PubMed/NCBI View Article : Google Scholar

23 

Eclov RJ, Kim MJ, Smith R, Ahituv N and Kroetz DL: Rare variants in the ABCG2 promoter modulate in vivo activity. Drug Metab Dispos. 46:636–642. 2018.PubMed/NCBI View Article : Google Scholar

24 

de Roda Husman AM, Walboomers JM, van den Brule AJ, Meijer CJ and Snijders PJ: The use of general primers GP5 and GP6 elongated at their 3' ends with adjacent highly conserved sequences improves human papillomavirus detection by PCR. J Gen Virol. 76:1057–1062. 1995.PubMed/NCBI View Article : Google Scholar

25 

Lilyquist J, Ruddy KJ, Vachon CM and Couch FJ: Common genetic variation and breast cancer risk-past, present, and future. Cancer Epidemiol Biomarkers Prev. 27:380–394. 2018.PubMed/NCBI View Article : Google Scholar

26 

Behravan H, Hartikainen JM, Tengström M, Kosma VM and Mannermaa A: Predicting breast cancer risk using interacting genetic and demographic factors and machine learning. Sci Rep. 10(11044)2020.PubMed/NCBI View Article : Google Scholar

27 

Sartor H, Brandt J, Grassmann F, Eriksson M, Czene K, Melander O and Zackrisson S: The association of single nucleotide polymorphisms (SNPs) with breast density and breast cancer survival: The Malmö diet and cancer study. Acta Radiol. 61:1326–1334. 2020.PubMed/NCBI View Article : Google Scholar

28 

Yang H, Ting X, Geng YH, Xie Y, Nierenberg JL, Huo YF, Zhou YT, Huang Y, Yu YQ, Yu XY, et al: The risk variant rs11836367 contributes to breast cancer onset and metastasis by attenuating Wnt signaling via regulating NTN4 expression. Sci Adv. 8(eabn3509)2022.PubMed/NCBI View Article : Google Scholar

29 

Sellers TA: Genetic factors in the pathogenesis of breast cancer: Their role and relative importance. J Nutr. 127 (5 Suppl):929S–932S. 1997.PubMed/NCBI View Article : Google Scholar

30 

De Silva S, Tennekoon KH and Karunanayake EH: Overview of the genetic basis toward early detection of breast cancer. Breast Cancer (Dove Med Press). 11:71–80. 2019.PubMed/NCBI View Article : Google Scholar

31 

Sokolova A, Johnstone KJ, McCart Reed AE, Simpson PT and Lakhani SR: Hereditary breast cancer: Syndromes, tumour pathology and molecular testing. Histopathology. 82:70–82. 2023.PubMed/NCBI View Article : Google Scholar

32 

Wendt C and Margolin S: Identifying breast cancer susceptibility genes-a review of the genetic background in familial breast cancer. Acta Oncol. 58:135–146. 2019.PubMed/NCBI View Article : Google Scholar

33 

Sun YS, Zhao Z, Yang ZN, Xu F, Lu HJ, Zhu ZY, Shi W, Jiang J, Yao PP and Zhu HP: Risk factors and preventions of breast cancer. Int J Biol Sci. 13:1387–1397. 2017.PubMed/NCBI View Article : Google Scholar

34 

Hill AD, Doyle JM, McDermott EW and O'Higgins NJ: Hereditary breast cancer. Br J Surg. 84:1334–1339. 1997.PubMed/NCBI

35 

Collins A and Politopoulos I: The genetics of breast cancer: Risk factors for disease. Appl Clin Genet. 4:11–19. 2011.PubMed/NCBI View Article : Google Scholar

36 

Kumaran M, Cass CE, Graham K, Mackey JR, Hubaux R, Lam W, Yasui Y and Damaraju S: Germline copy number variations are associated with breast cancer risk and prognosis. Sci Rep. 7(14621)2017.PubMed/NCBI View Article : Google Scholar

37 

Pan X, Hu X, Zhang YH, Chen L, Zhu L, Wan S, Huang T and Cai YD: Identification of the copy number variant biomarkers for breast cancer subtypes. Mol Genet Genomics. 294:95–110. 2019.PubMed/NCBI View Article : Google Scholar

38 

Dennis J, Tyrer JP, Walker LC, Michailidou K, Dorling L, Bolla MK, Wang Q, Ahearn TU, Andrulis IL, Anton-Culver H, et al: Rare germline copy number variants (CNVs) and breast cancer risk. Commun Biol. 5(65)2022.PubMed/NCBI View Article : Google Scholar

39 

Zhang W and Yu Y: The important molecular markers on chromosome 17 and their clinical impact in breast cancer. Int J Mol Sci. 12:5672–5683. 2011.PubMed/NCBI View Article : Google Scholar

40 

Chen C, Lin CJ, Pei YC, Ma D, Liao L, Li SY, Fan L, Di GH, Wu SY, Liu XY, et al: Comprehensive genomic profiling of breast cancers characterizes germline-somatic mutation interactions mediating therapeutic vulnerabilities. Cell Discov. 9(125)2023.PubMed/NCBI View Article : Google Scholar

41 

Lertwilaiwittaya P, Roothumnong E, Nakthong P, Dungort P, Meesamarnpong C, Tansa-Nga W, Pongsuktavorn K, Wiboonthanasarn S, Tititumjariya W, Thongnoppakhun W, et al: Thai patients who fulfilled NCCN criteria for breast/ovarian cancer genetic assessment demonstrated high prevalence of germline mutations in cancer susceptibility genes: Implication to Asian population testing. Breast Cancer Res Treat. 188:237–248. 2021.PubMed/NCBI View Article : Google Scholar

42 

Sukpan P, Sangkhathat S, Sriplung H, Laochareonsuk W, Choochuen P, Auseng N, Khoonjan W, Salaeh R, Thangnaphadol K, Wanawanakorn K and Kanokwiroon K: Exome sequencing reveals novel germline variants in breast cancer patients in the southernmost region of Thailand. J Pers Med. 13(1587)2023.PubMed/NCBI View Article : Google Scholar

43 

Manchanda R, Patel S, Gordeev VS, Antoniou AC, Smith S, Lee A, Hopper JL, MacInnis RJ, Turnbull C, Ramus SJ, et al: Cost-effectiveness of population-based BRCA1, BRCA2, RAD51C, RAD51D, BRIP1, PALB2 mutation testing in unselected general population women. J Natl Cancer Inst. 110:714–725. 2018.PubMed/NCBI View Article : Google Scholar

44 

Nicoloso MS, Sun H, Spizzo R, Kim H, Wickramasinghe P, Shimizu M, Wojcik SE, Ferdin J, Kunej T, Xiao L, et al: Single-nucleotide polymorphisms inside microRNA target sites influence tumor susceptibility. Cancer Res. 70:2789–2798. 2010.PubMed/NCBI View Article : Google Scholar

45 

Smolarz B, Bryś M, Forma E, Zadrożny M, Bieńkiewicz J and Romanowicz H: Data on single nucleotide polymorphism of DNA repair genes and breast cancer risk from Poland. Pathol Oncol Res. 25:1311–1317. 2019.PubMed/NCBI View Article : Google Scholar

46 

Ahmad J, Le Calvez-Kelm F, Daud S, Voegele C, Vallée M, Ahmad A, Kakar N, McKay JD, Gaborieau V, Léoné M, et al: Detection of BRCA1/2 mutations in breast cancer patients from Thailand and Pakistan. Clin Genet. 82:594–598. 2012.PubMed/NCBI View Article : Google Scholar

47 

Stiburkova B, Pavelcova K, Zavada J, Petru L, Simek P, Cepek P, Pavlikova M, Matsuo H, Merriman TR and Pavelka K: Functional non-synonymous variants of ABCG2 and gout risk. Rheumatology (Oxford). 56:1982–1992. 2017.PubMed/NCBI View Article : Google Scholar

48 

Toyoda Y, Pavelcová K, Bohatá J, Ješina P, Kubota Y, Suzuki H, Takada T and Stiburkova B: Identification of two dysfunctional variants in the ABCG2 urate transporter associated with pediatric-onset of familial hyperuricemia and early-onset gout. Int J Mol Sci. 22(1935)2021.PubMed/NCBI View Article : Google Scholar

49 

Keskitalo JE, Zolk O, Fromm MF, Kurkinen KJ, Neuvonen PJ and Niemi M: ABCG2 polymorphism markedly affects the pharmacokinetics of atorvastatin and rosuvastatin. Clin Pharmacol Ther. 86:197–203. 2009.PubMed/NCBI View Article : Google Scholar

50 

Phan L, Jin H, Zhang W, Qiang E, Shekhtman D, Shao D, Revoe R, Villamarin E, Ivanchenko M, Kimura ZY, et al: ‘ALFA: Allele frequency aggregator’. national center for biotechnology information, U.S. National Library of Medicine, 10 Mar, 2020. www.ncbi.nlm.nih.gov/snp/docs/gsr/alfa/.

51 

Bircsak KM, Moscovitz JE, Wen X, Archer F, Yuen PYS, Mohammed M, Memon N, Weinberger BI, Saba LM, Vetrano AM, et al: Interindividual regulation of the breast cancer resistance protein/ABCG2 transporter in term human placentas. Drug Metab Dispos. 46:619–627. 2018.PubMed/NCBI View Article : Google Scholar

52 

Ngamkham J, Karalak A, Chaiwerawattana A, Sornprom A, Thanasutthichai S, Sukarayodhin S, Mus-u-Dee M, Boonmark K, Phansri T and Laochan N: Prevalence of human papillomavirus infection in breast cancer cells from Thai women. Asian Pac J Cancer Prev. 18:1839–1845. 2017.PubMed/NCBI View Article : Google Scholar

53 

Bumrungthai S, Ekalaksananan T, Duangchai D, Lanpol P, Panya P, Kattiwong F, Acharya S and Pientong C: Prevalence of human papillomavirus in oral rinse samples from healthy individuals in northern Thailand. J Oral Pathol Med. 48:159–165. 2019.PubMed/NCBI View Article : Google Scholar

Related Articles

  • Abstract
  • View
  • Download
  • Twitter
Copy and paste a formatted citation
Spandidos Publications style
Bumrungthai S, Duangjit S, Passorn S, Pongpakdeesakul S, Butsri S and Janyakhantikul S: Comprehensive breast cancer risk analysis with whole exome sequencing and the prevalence of <em>BRCA1</em> and <em>ABCG2</em> mutations and oncogenic HPV. Biomed Rep 21: 144, 2024.
APA
Bumrungthai, S., Duangjit, S., Passorn, S., Pongpakdeesakul, S., Butsri, S., & Janyakhantikul, S. (2024). Comprehensive breast cancer risk analysis with whole exome sequencing and the prevalence of <em>BRCA1</em> and <em>ABCG2</em> mutations and oncogenic HPV. Biomedical Reports, 21, 144. https://doi.org/10.3892/br.2024.1832
MLA
Bumrungthai, S., Duangjit, S., Passorn, S., Pongpakdeesakul, S., Butsri, S., Janyakhantikul, S."Comprehensive breast cancer risk analysis with whole exome sequencing and the prevalence of <em>BRCA1</em> and <em>ABCG2</em> mutations and oncogenic HPV". Biomedical Reports 21.4 (2024): 144.
Chicago
Bumrungthai, S., Duangjit, S., Passorn, S., Pongpakdeesakul, S., Butsri, S., Janyakhantikul, S."Comprehensive breast cancer risk analysis with whole exome sequencing and the prevalence of <em>BRCA1</em> and <em>ABCG2</em> mutations and oncogenic HPV". Biomedical Reports 21, no. 4 (2024): 144. https://doi.org/10.3892/br.2024.1832
Copy and paste a formatted citation
x
Spandidos Publications style
Bumrungthai S, Duangjit S, Passorn S, Pongpakdeesakul S, Butsri S and Janyakhantikul S: Comprehensive breast cancer risk analysis with whole exome sequencing and the prevalence of <em>BRCA1</em> and <em>ABCG2</em> mutations and oncogenic HPV. Biomed Rep 21: 144, 2024.
APA
Bumrungthai, S., Duangjit, S., Passorn, S., Pongpakdeesakul, S., Butsri, S., & Janyakhantikul, S. (2024). Comprehensive breast cancer risk analysis with whole exome sequencing and the prevalence of <em>BRCA1</em> and <em>ABCG2</em> mutations and oncogenic HPV. Biomedical Reports, 21, 144. https://doi.org/10.3892/br.2024.1832
MLA
Bumrungthai, S., Duangjit, S., Passorn, S., Pongpakdeesakul, S., Butsri, S., Janyakhantikul, S."Comprehensive breast cancer risk analysis with whole exome sequencing and the prevalence of <em>BRCA1</em> and <em>ABCG2</em> mutations and oncogenic HPV". Biomedical Reports 21.4 (2024): 144.
Chicago
Bumrungthai, S., Duangjit, S., Passorn, S., Pongpakdeesakul, S., Butsri, S., Janyakhantikul, S."Comprehensive breast cancer risk analysis with whole exome sequencing and the prevalence of <em>BRCA1</em> and <em>ABCG2</em> mutations and oncogenic HPV". Biomedical Reports 21, no. 4 (2024): 144. https://doi.org/10.3892/br.2024.1832
Follow us
  • Twitter
  • LinkedIn
  • Facebook
About
  • Spandidos Publications
  • Careers
  • Cookie Policy
  • Privacy Policy
How can we help?
  • Help
  • Live Chat
  • Contact
  • Email to our Support Team