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Review Open Access

Unlocking the potential of capsaicin in oral health (Review)

  • Authors:
    • Winny Yohana
    • Anggun Rafisa
  • View Affiliations / Copyright

    Affiliations: Department of Oral Biology, Faculty of Dentistry, Universitas Padjadjaran, Sumedang, West Java 45363, Indonesia
    Copyright: © Yohana et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Article Number: 153
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    Published online on: August 22, 2024
       https://doi.org/10.3892/br.2024.1841
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Abstract

Capsaicin is a bioactive compound found prominently in Capsicum annuum L. plants and takes on a pivotal role in their characteristic spiciness. Previous studies have delved into the potential analgesic effect of capsaicin in various oral conditions, such as oral neuropathic pain, trigeminal neuralgia, oral mucositis, temporomandibular joint disorders and burning mouth syndrome. Capsaicin has also demonstrated promise in inhibiting the proliferation of different oral cancer cell lines. Its antimicrobial properties have also been shown to inhibit the growth of oral pathogens associated with dental caries, periodontitis and oral candidiasis. However, to harness its benefits effectively, more studies are required to establish optimal dosages for pain relief while minimizing adverse effects. In addition, investigation of the effect of capsaicin on nonpathogenic oral bacteria and viruses is warranted. Human‑based research is crucial for elucidating the biomolecular mechanisms underlying the properties of capsaicin, potentially leading to the development of more effective interventions for oral health problems.
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Copy and paste a formatted citation
Spandidos Publications style
Yohana W and Rafisa A: Unlocking the potential of capsaicin in oral health (Review). Biomed Rep 21: 153, 2024.
APA
Yohana, W., & Rafisa, A. (2024). Unlocking the potential of capsaicin in oral health (Review). Biomedical Reports, 21, 153. https://doi.org/10.3892/br.2024.1841
MLA
Yohana, W., Rafisa, A."Unlocking the potential of capsaicin in oral health (Review)". Biomedical Reports 21.5 (2024): 153.
Chicago
Yohana, W., Rafisa, A."Unlocking the potential of capsaicin in oral health (Review)". Biomedical Reports 21, no. 5 (2024): 153. https://doi.org/10.3892/br.2024.1841
Copy and paste a formatted citation
x
Spandidos Publications style
Yohana W and Rafisa A: Unlocking the potential of capsaicin in oral health (Review). Biomed Rep 21: 153, 2024.
APA
Yohana, W., & Rafisa, A. (2024). Unlocking the potential of capsaicin in oral health (Review). Biomedical Reports, 21, 153. https://doi.org/10.3892/br.2024.1841
MLA
Yohana, W., Rafisa, A."Unlocking the potential of capsaicin in oral health (Review)". Biomedical Reports 21.5 (2024): 153.
Chicago
Yohana, W., Rafisa, A."Unlocking the potential of capsaicin in oral health (Review)". Biomedical Reports 21, no. 5 (2024): 153. https://doi.org/10.3892/br.2024.1841
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