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Chemical composition and pharmacological aspects of Malaysian stingless bee propolis: An up‑to‑date systematic review

  • Authors:
    • Nor Atiqah Jusril
    • Khamsah Suryati Mohd
    • Nurliana Abd Mutalib
    • Ainur Awanis Mohd Badiazaman
  • View Affiliations / Copyright

    Affiliations: School of Agriculture Science and Biotechnology, Faculty of Bioresources and Food Industry, Universiti Sultan Zainal Abidin, Besut Campus, 22200 Besut, Terengganu Darul Iman, Malaysia, Atta‑ur‑Rahman Institute for Natural Product Discovery (AuRIns), Level 9, FF3 Puncak Alam Campus, Universiti Teknologi MARA, 42300 Puncak Alam, Selangor Darul Ehsan, Malaysia, Faculty of Applied Sciences, Universiti Teknologi MARA, 26400 Bandar Tun Abdul Razak Jengka, Pahang, Malaysia
    Copyright: © Jusril et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Article Number: 9
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    Published online on: November 5, 2024
       https://doi.org/10.3892/br.2024.1887
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Abstract

Propolis is a sticky substance produced by stingless bees for construction and defence of their hive. It has notable anti‑inflammatory, antioxidant, antibacterial, antifungal, anti‑hyperglycemic, and wound healing effects. The present review summarised and examined the phytochemical properties, mode of action and current research prospects of Malaysian propolis. A database search using Google Scholar, Web of Science and ScienceDirect generated 780 references; 30 relevant articles were included in the present review, of which 23 were in vitro studies and 7 were in vivo or animal studies. Propolis demonstrated antioxidant, antibacterial, antifungal, anti‑inflammatory and anti‑hyperglycemic properties, indicating potential as a wound healing agent. Despite favourable findings, due to the scarcity of studies in the literature, more in‑depth research and clinical validation on the synergistic effects, efficacy and optimum dosage of propolis are needed.
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Copy and paste a formatted citation
Spandidos Publications style
Jusril NA, Mohd KS, Abd Mutalib N and Mohd Badiazaman AA: Chemical composition and pharmacological aspects of Malaysian stingless bee propolis: An up‑to‑date systematic review. Biomed Rep 22: 9, 2025.
APA
Jusril, N.A., Mohd, K.S., Abd Mutalib, N., & Mohd Badiazaman, A.A. (2025). Chemical composition and pharmacological aspects of Malaysian stingless bee propolis: An up‑to‑date systematic review. Biomedical Reports, 22, 9. https://doi.org/10.3892/br.2024.1887
MLA
Jusril, N. A., Mohd, K. S., Abd Mutalib, N., Mohd Badiazaman, A. A."Chemical composition and pharmacological aspects of Malaysian stingless bee propolis: An up‑to‑date systematic review". Biomedical Reports 22.1 (2025): 9.
Chicago
Jusril, N. A., Mohd, K. S., Abd Mutalib, N., Mohd Badiazaman, A. A."Chemical composition and pharmacological aspects of Malaysian stingless bee propolis: An up‑to‑date systematic review". Biomedical Reports 22, no. 1 (2025): 9. https://doi.org/10.3892/br.2024.1887
Copy and paste a formatted citation
x
Spandidos Publications style
Jusril NA, Mohd KS, Abd Mutalib N and Mohd Badiazaman AA: Chemical composition and pharmacological aspects of Malaysian stingless bee propolis: An up‑to‑date systematic review. Biomed Rep 22: 9, 2025.
APA
Jusril, N.A., Mohd, K.S., Abd Mutalib, N., & Mohd Badiazaman, A.A. (2025). Chemical composition and pharmacological aspects of Malaysian stingless bee propolis: An up‑to‑date systematic review. Biomedical Reports, 22, 9. https://doi.org/10.3892/br.2024.1887
MLA
Jusril, N. A., Mohd, K. S., Abd Mutalib, N., Mohd Badiazaman, A. A."Chemical composition and pharmacological aspects of Malaysian stingless bee propolis: An up‑to‑date systematic review". Biomedical Reports 22.1 (2025): 9.
Chicago
Jusril, N. A., Mohd, K. S., Abd Mutalib, N., Mohd Badiazaman, A. A."Chemical composition and pharmacological aspects of Malaysian stingless bee propolis: An up‑to‑date systematic review". Biomedical Reports 22, no. 1 (2025): 9. https://doi.org/10.3892/br.2024.1887
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