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Typical presentation of neurofibromatosis type I in a patient with giant cutaneous neoplasm and café au lait spots: A case report

  • Authors:
    • Chenguang Zhang
    • Yilina Saibaidula
    • Yulou Luo
    • Jianghua Ou
  • View Affiliations / Copyright

    Affiliations: Department of Breast Surgery, Affiliated Tumor Hospital of Xinjiang Medical University, Urumqi, Xinjiang Uyghur Autonomous Region 830000, P.R. China
    Copyright: © Zhang et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Article Number: 27
    |
    Published online on: December 5, 2024
       https://doi.org/10.3892/br.2024.1905
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Abstract

Neurofibromatosis type 1 (NF1), which is also known as von Recklinghausen's disease, is a multisystem genetic disease that is principally associated with cutaneous, neurologic and orthopedic manifestations. The present case report described an unusual case with a giant cutaneous neoplasm on the right breast skin of a 36‑year‑old female who was admitted to the Department of Breast Surgery at the Affiliated Tumor Hospital of Xinjiang Medical University (Urumqi, China). Skin mass excision was performed and histopathology confirmed the diagnosis of thoracic plexiform neurofibroma as a primary presentation of NF1. The clinical implementation of NF1 therapies necessitates meticulous consideration of various factors and should involve a multidisciplinary team with expertise in NF1.
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Copy and paste a formatted citation
Spandidos Publications style
Zhang C, Saibaidula Y, Luo Y and Ou J: Typical presentation of neurofibromatosis type I in a patient with giant cutaneous neoplasm and café au lait spots: A case report. Biomed Rep 22: 27, 2025.
APA
Zhang, C., Saibaidula, Y., Luo, Y., & Ou, J. (2025). Typical presentation of neurofibromatosis type I in a patient with giant cutaneous neoplasm and café au lait spots: A case report. Biomedical Reports, 22, 27. https://doi.org/10.3892/br.2024.1905
MLA
Zhang, C., Saibaidula, Y., Luo, Y., Ou, J."Typical presentation of neurofibromatosis type I in a patient with giant cutaneous neoplasm and café au lait spots: A case report". Biomedical Reports 22.2 (2025): 27.
Chicago
Zhang, C., Saibaidula, Y., Luo, Y., Ou, J."Typical presentation of neurofibromatosis type I in a patient with giant cutaneous neoplasm and café au lait spots: A case report". Biomedical Reports 22, no. 2 (2025): 27. https://doi.org/10.3892/br.2024.1905
Copy and paste a formatted citation
x
Spandidos Publications style
Zhang C, Saibaidula Y, Luo Y and Ou J: Typical presentation of neurofibromatosis type I in a patient with giant cutaneous neoplasm and café au lait spots: A case report. Biomed Rep 22: 27, 2025.
APA
Zhang, C., Saibaidula, Y., Luo, Y., & Ou, J. (2025). Typical presentation of neurofibromatosis type I in a patient with giant cutaneous neoplasm and café au lait spots: A case report. Biomedical Reports, 22, 27. https://doi.org/10.3892/br.2024.1905
MLA
Zhang, C., Saibaidula, Y., Luo, Y., Ou, J."Typical presentation of neurofibromatosis type I in a patient with giant cutaneous neoplasm and café au lait spots: A case report". Biomedical Reports 22.2 (2025): 27.
Chicago
Zhang, C., Saibaidula, Y., Luo, Y., Ou, J."Typical presentation of neurofibromatosis type I in a patient with giant cutaneous neoplasm and café au lait spots: A case report". Biomedical Reports 22, no. 2 (2025): 27. https://doi.org/10.3892/br.2024.1905
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