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Article Open Access

Oral health and sleep disorders: A systematic review and meta-analysis

  • Authors:
    • Fei Lei
    • Xiaotao Hu
  • View Affiliations / Copyright

    Affiliations: Department of Stomatology, Second Affiliated Hospital of Xi'an Medical University, Xi'an, Shaanxi 710000, P.R. China, Department of Stomatology, Shaanxi Province Second People's Hospital (Shaanxi Province Geriatric Hospital), Xi'an, Shaanxi 710000, P.R. China
    Copyright: © Lei et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Article Number: 37
    |
    Published online on: December 20, 2024
       https://doi.org/10.3892/br.2024.1915
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Abstract

Oral health and sleep quality are critical components of overall health, but their relationship remains poorly understood. The present meta-analysis therefore investigates the association between oral health and sleep quality, synthesizing evidence from diverse populations. To this aim, a comprehensive search strategy identified 311 articles, from which 8 studies encompassing 18 comparisons met the inclusion criteria. These studies, conducted between 2015 and 2023, included 36,559 participants across various countries. Oral health was assessed using indices such as the Decayed, Missing, and Filled Teeth Index and gingival indices. At the same time, sleep quality was measured using tools such as the Pittsburgh Sleep Quality Index and Epworth Sleepiness Scale. The results of the meta-analysis revealed a significant association between poorer oral health and poorer sleep quality, with a standardized mean difference of 2.166 [95% confidence interval (95% CI), 0.677-3.655; P=0.004]. Sensitivity analyses confirmed the robustness of the findings, and publication bias assessments indicated no significant bias. Precision interval analysis showed a mean effect size of 2.17 with a 95% CI of -4.83 to 9.16, suggesting variability in the strength of the association across populations. In conclusion, the results of the present meta-analysis provide strong evidence for a significant link between oral health and sleep quality, highlighting the importance of considering oral health in the management of sleep disorders. Future research should focus on longitudinal studies and standardized measurement tools to further elucidate this relationship and inform public health strategies aimed at improving both oral health and sleep quality.
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1 

Asawa K, Sen N, Bhat N, Tak M, Sultane P and Mandal A: Influence of sleep disturbance, fatigue, vitality on oral health and academic performance in Indian dental students. Clujul Med. 90:333–343. 2017.PubMed/NCBI View Article : Google Scholar

2 

Schroeder K and Gurenlian JR: Recognizing poor sleep quality factors during oral health evaluations. Clin Med Res. 17:20–28. 2019.PubMed/NCBI View Article : Google Scholar

3 

Alqaderi H, Tavares M, Hartman M and Goodson JM: Effect of sleep and salivary glucose on gingivitis in children. J Dent Res. 95:1387–1393. 2016.PubMed/NCBI View Article : Google Scholar

4 

Movahed E, Moradi S, Mortezagholi B, Shafiee A, Moltazemi H, Hajishah H, Siahvoshi S, Monfared AB, Amini MJ, Safari F and Bakhtiyari M: Investigating oral health among US adults with sleep disorder: A cross-sectional study. BMC Oral Health. 23(996)2023.PubMed/NCBI View Article : Google Scholar

5 

Grillo C, La Mantia I, Zappala G, Cocuzza S, Ciprandi G and Andaloro C: Oral health in children with sleep-disordered breathing: A cross-sectional study. Acta Biomed. 90:52–59. 2019.PubMed/NCBI View Article : Google Scholar

6 

Carra MC, Schmitt A, Thomas F, Danchin N, Pannier B and Bouchard P: Sleep disorders and oral health: A cross-sectional study. Clin Oral Investig. 21:975–983. 2017.PubMed/NCBI View Article : Google Scholar

7 

Safak ED, Celik F, Mazicioglu MM, Akin S, Manav TY, Kesim S and Ozturk A: The relationship between oral health and sleep quality in community-dwelling older adults. Niger J Clin Pract. 26:1449–1455. 2023.PubMed/NCBI View Article : Google Scholar

8 

Taştan Eroğlu Z, Özkan Şen D, Uçan Yarkac F and Altiparmak F: The association between sleep quality, fatigue and periodontal status: A pilot study. Odovtos Int J Dent Sci. 25:99–117. 2023.

9 

Hirotsu C, Tufik S and Andersen ML: Interactions between sleep, stress, and metabolism: From physiological to pathological conditions. Sleep Sci. 8:143–152. 2015.PubMed/NCBI View Article : Google Scholar

10 

Wiener RC: Relationship of routine inadequate sleep duration and periodontitis in a nationally representative sample. Sleep Disord. 2016(9158195)2016.PubMed/NCBI View Article : Google Scholar

11 

Beydoun HA, Hossain S, Beydoun MA, Weiss J, Zonderman AB and Eid SM: Periodontal disease, sleep duration, and white blood cell markers in the 2009 to 2014 National Health and Nutrition Examination Surveys. J Periodontol. 91:582–595. 2020.PubMed/NCBI View Article : Google Scholar

12 

Corker KS: Strengths and weaknesses of meta-analyses. In: Research Integrity: Best Practices for the Social and Behavioral Sciences. Jussim L, Krosnick JA and Stevens ST (eds). Oxford University Press, Oxford, pp150-174, 2022.

13 

Page MJ, McKenzie JE, Bossuyt PM, Boutron I, Hoffmann TC, Mulrow CD, Shamseer L, Tetzlaff JM, Akl EA, Brennan SE, et al: The PRISMA 2020 statement: An updated guideline for reporting systematic reviews. BMJ. 372(n71)2021.PubMed/NCBI View Article : Google Scholar

14 

Peterson J, Welch V, Losos M and Tugwell P: The Newcastle-Ottawa scale (NOS) for assessing the quality of nonrandomised studies in meta-analyses. Ottawa: Ottawa Hospital Research Institute. 2:1–12. 2011.

15 

IntHout J, Ioannidis JP, Rovers MM and Goeman JJ: Plea for routinely presenting prediction intervals in meta-analysis. BMJ Open. 6(e010247)2016.PubMed/NCBI View Article : Google Scholar

16 

Apessos I, Andreadis D, Steiropoulos P, Tortopidis D and Angelis L: Investigation of the relationship between sleep disorders and xerostomia. Clin Oral Investig. 24:1709–1716. 2020.PubMed/NCBI View Article : Google Scholar

17 

Arroyo Buenestado A and Ribas-Pérez D: Early childhood caries and sleep disorders. J Clin Med. 12(1378)2023.PubMed/NCBI View Article : Google Scholar

18 

Chacko NL, Raje M, Rakhewar P and Bhamare R: The association between sleep deprivation and periodontitis: A cross sectional study. IOSR J Dent Med Sci (IOSR-JDMS). 20:1–8. 2021.

19 

Grover V, Malhotra R and Kaur H: Exploring association between sleep deprivation and chronic periodontitis: A pilot study. J Indian Soc Periodontol. 19:304–307. 2015.PubMed/NCBI View Article : Google Scholar

20 

Romandini M, Gioco G, Perfetti G, Deli G, Staderini E and Laforì A: The association between periodontitis and sleep duration. J Clin Periodontol. 44:490–501. 2017.PubMed/NCBI View Article : Google Scholar

21 

Tamasa B, Godfrey G, Nelson T and Chen M: Oral health status of children with high risk of sleep-disordered breathing. J Dent Sleep Med. 5:31–38. 2018.

22 

Pereira D, Progiante P, Pattussi M, Grossi P and Grossi M: Study on the association between sleep disorders versus oral health related variables. Med Oral Patol Oral Cir Bucal. 26:e164–e71. 2021.PubMed/NCBI View Article : Google Scholar

23 

Han S, Jee D, Kang YJ, Park YJ and Cho JH: Possible association between oral health and sleep duration: A cross-sectional study based on the Korean National Health and Nutrition Examination Surveys from 2010 to 2015. Medicine (Baltimore). 100(e28035)2021.PubMed/NCBI View Article : Google Scholar

24 

Alawady A, Alharbi A, Alharbi H, Almesbah S, Alshammari N, Alkandari A, Alhazmi H and Alqaderi H: Association between sleep duration and dental caries in a nationally representative U.S. population. BMC Oral Health. 23(497)2023.PubMed/NCBI View Article : Google Scholar

25 

Ju X, Hedges J, Sethi S and Jamieson LM: Poor self-rated sleep quality and quantity associated with poor oral health-related quality of life among indigenous Australian adults. Int J Environ Res Public Health. 21(453)2024.PubMed/NCBI View Article : Google Scholar

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Copy and paste a formatted citation
Spandidos Publications style
Lei F and Hu X: Oral health and sleep disorders: A systematic review and meta-analysis. Biomed Rep 22: 37, 2025.
APA
Lei, F., & Hu, X. (2025). Oral health and sleep disorders: A systematic review and meta-analysis. Biomedical Reports, 22, 37. https://doi.org/10.3892/br.2024.1915
MLA
Lei, F., Hu, X."Oral health and sleep disorders: A systematic review and meta-analysis". Biomedical Reports 22.3 (2025): 37.
Chicago
Lei, F., Hu, X."Oral health and sleep disorders: A systematic review and meta-analysis". Biomedical Reports 22, no. 3 (2025): 37. https://doi.org/10.3892/br.2024.1915
Copy and paste a formatted citation
x
Spandidos Publications style
Lei F and Hu X: Oral health and sleep disorders: A systematic review and meta-analysis. Biomed Rep 22: 37, 2025.
APA
Lei, F., & Hu, X. (2025). Oral health and sleep disorders: A systematic review and meta-analysis. Biomedical Reports, 22, 37. https://doi.org/10.3892/br.2024.1915
MLA
Lei, F., Hu, X."Oral health and sleep disorders: A systematic review and meta-analysis". Biomedical Reports 22.3 (2025): 37.
Chicago
Lei, F., Hu, X."Oral health and sleep disorders: A systematic review and meta-analysis". Biomedical Reports 22, no. 3 (2025): 37. https://doi.org/10.3892/br.2024.1915
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