|
1
|
Kassebaum NJ, Smith AGC, Bernabé E,
Fleming TD, Reynolds AE, Vos T, Murray CJL and Marcenes W: GBD 2015
Oral Health Collaborators. Global, regional, and national
prevalence, incidence, and disability-adjusted life years for oral
conditions for 195 countries, 1990-2015: A systematic analysis for
the global burden of diseases, injuries, and risk factors. J Dent
Res. 96:380–387. 2017.PubMed/NCBI View Article : Google Scholar
|
|
2
|
Periodontal diseases-level 4 cause. Global
Health Metrics. https://www.thelancet.com/pb-assets/Lancet/gbd/summaries/diseases/periodontal-diseases.pdf.
|
|
3
|
Socransky SS, Haffajee AD, Cugini MA,
Smith C and Kent RL Jr: Microbial complexes in subgingival plaque.
J Clin Periodontol. 25:134–144. 1998.PubMed/NCBI View Article : Google Scholar
|
|
4
|
Cochran DL: Inflammation and bone loss in
periodontal disease. J Periodontol. 79 (Suppl 8):S1569–S1576.
2008.PubMed/NCBI View Article : Google Scholar
|
|
5
|
Hajishengallis G and Chavakis T: Local and
systemic mechanisms linking periodontal disease and inflammatory
comorbidities. Nat Rev Immunol. 21:426–440. 2021.PubMed/NCBI View Article : Google Scholar
|
|
6
|
Balta MG, Papathanasiou E, Blix IJ and Van
Dyke TE: Host modulation and treatment of periodontal disease. J
Dent Res. 100:798–809. 2021.PubMed/NCBI View Article : Google Scholar
|
|
7
|
Ito T, Yoshida Y, Shiota Y, Ito Y,
Yamamoto T and Takashiba S: Effects of Lectins on initial
attachment of cariogenic Streptococcus mutans. Glycoconj J.
35:41–51. 2018.PubMed/NCBI View Article : Google Scholar
|
|
8
|
Ito M, Ito T, Aoki H, Nishioka K, Shiokawa
T, Tada H, Takeuchi Y, Takeyasu N, Yamamoto T and Takashiba S:
Isolation and identification of the antimicrobial substance
included in tempeh using Rhizopus stolonifer NBRC 30816 for
fermentation. Int J Food Microbiol. 325(108645)2020.PubMed/NCBI View Article : Google Scholar
|
|
9
|
Siddiqui YD, Omori K, Ito T, Yamashiro K,
Nakamura S, Okamoto K, Ono M, Yamamoto T, Van Dyke TE and Takashiba
S: Resolvin D2 induces resolution of periapical inflammation and
promotes healing of periapical lesions in rat periapical
periodontitis. Front Immunol. 10(307)2019.PubMed/NCBI View Article : Google Scholar
|
|
10
|
Huang L, Liu Z, Wang J, Fu J, Jia Y, Ji L
and Wang T: Bioactivity and health effects of garlic essential oil:
A review. Food Sci Nutr. 11:2450–2470. 2023.PubMed/NCBI View Article : Google Scholar
|
|
11
|
Grant JK, Dangl M, Ndumele CE, Michos ED
and Martin SS: A historical, evidence-based, and narrative review
on commonly used dietary supplements in lipid-lowering. J Lipid
Res. 65(100493)2024.PubMed/NCBI View Article : Google Scholar
|
|
12
|
Verma T, Aggarwal A, Dey P, Chauhan AK,
Rashid S, Chen KT and Sharma R: Medicinal and therapeutic
properties of garlic, garlic essential oil, and garlic-based snack
food: An updated review. Front Nutr. 10(1120377)2023.PubMed/NCBI View Article : Google Scholar
|
|
13
|
Sunanta P, Kontogiorgos V, Pankasemsuk T,
Jantanasakulwong K, Rachtanapun P, Seesuriyachan P and Sommano SR:
The nutritional value, bioactive availability and functional
properties of garlic and its related products during processing.
Front Nutr. 10(1142784)2023.PubMed/NCBI View Article : Google Scholar
|
|
14
|
Zini A, Mann J, Mazor S and Vered Y: The
efficacy of aged garlic extract on gingivitis-a randomized clinical
trial. J Clin Dent. 29:52–56. 2018.PubMed/NCBI
|
|
15
|
Zini A, Mann J, Mazor S and Vered Y:
Beneficial effect of aged garlic extract on periodontitis: A
randomized controlled double-blind clinical study. J Clin Biochem
Nutr. 67:297–301. 2020.PubMed/NCBI View Article : Google Scholar
|
|
16
|
Takahashi K, Nango H, Ushijima M,
Takashima M, Nakamoto M, Matsutomo T, Jikihara H, Arakawa N, Maki
S, Yabuki A, et al: Therapeutic effect of aged garlic extract on
gingivitis in dogs. Front Vet Sci. 10(1277272)2023.PubMed/NCBI View Article : Google Scholar
|
|
17
|
Morihara N, Hayama M and Fujii H: Aged
garlic extract scavenges superoxide radicals. Plant Foods Hum Nutr.
66:17–21. 2011.PubMed/NCBI View Article : Google Scholar
|
|
18
|
Wang X, Yang Y and Zhang M: The vivo
antioxidant activity of self-made aged garlic extract on the
d-galactose-induced mice and its mechanism research via gene chip
analysis. RSC Adv. 9:3669–3678. 2019.PubMed/NCBI View Article : Google Scholar
|
|
19
|
Ushijima M, Takashima M, Kunimura K,
Kodera Y, Morihara N and Tamura K: Effects of S-1-propenylcysteine,
a sulfur compound in aged garlic extract, on blood pressure and
peripheral circulation in spontaneously hypertensive rats. J Pharm
Pharmacol. 70:559–565. 2018.PubMed/NCBI View Article : Google Scholar
|
|
20
|
Kim MJ, Yoo YC, Kim HJ, Shin SK, Sohn EJ,
Min AY, Sung NY and Kim MR: Aged black garlic exerts
anti-inflammatory effects by decreasing no and proinflammatory
cytokine production with less cytoxicity in LPS-stimulated raw
264.7 macrophages and LPS-induced septicemia mice. J Med Food.
17:1057–1063. 2014.PubMed/NCBI View Article : Google Scholar
|
|
21
|
Suzuki JI, Kodera Y, Miki S, Ushijima M,
Takashima M, Matsutomo T and Morihara N: Anti-inflammatory action
of cysteine derivative S-1-propenylcysteine by inducing MyD88
degradation. Sci Rep. 8(14148)2018.PubMed/NCBI View Article : Google Scholar
|
|
22
|
Ahmadabad HN, Hassan ZM, Safari E,
Bozorgmehr M, Ghazanfari T and Moazzeni SM: Evaluation of the
immunomodulatory effect of the 14 kDa protein isolated from aged
garlic extract on dendritic cells. Cell Immunol. 269:90–95.
2011.PubMed/NCBI View Article : Google Scholar
|
|
23
|
Kyo E, Uda N, Kasuga S and Itakura Y:
Immunomodulatory effects of aged garlic extract. J Nutr. 131
(Supple 3):1075S–1079S. 2001.PubMed/NCBI View Article : Google Scholar
|
|
24
|
Ohtani M and Nishimura T:
Sulfur-containing amino acids in aged garlic extract inhibit
inflammation in human gingival epithelial cells by suppressing
intercellular adhesion molecule-1 expression and IL-6 secretion.
Biomed Rep. 12:99–108. 2020.PubMed/NCBI View Article : Google Scholar
|
|
25
|
Nango H and Ohtani M:
S-1-propenyl-L-cysteine suppresses lipopolysaccharide-induced
expression of matrix metalloproteinase-1 through inhibition of
tumor necrosis factor-α converting enzyme-epidermal growth factor
receptor axis in human gingival fibroblasts. PLoS One.
18(e0284713)2023.PubMed/NCBI View Article : Google Scholar
|
|
26
|
Ohtani M and Nishimura T: The preventive
and therapeutic application of garlic and other plant ingredients
in the treatment of periodontal diseases. Exp Ther Med.
19:1507–1510. 2020.PubMed/NCBI View Article : Google Scholar
|
|
27
|
Ryu K, Ide N, Matsuura H and Itakura Y: N
alpha-(1-deoxy-D-fructos-1-yl)-L-arginine, an antioxidant compound
identified in aged garlic extract. J Nutr. 131 (Suppl 3):972S–976S.
2001.PubMed/NCBI View Article : Google Scholar
|
|
28
|
Matsutomo T, Ushijima M, Kodera Y,
Nakamoto M, Takashima M, Morihara N and Tamura K: Metabolomic study
on the antihypertensive effect of S-1-propenylcysteine in
spontaneously hypertensive rats using liquid chromatography coupled
with quadrupole-Orbitrap mass spectrometry. J Chromatogr B Analyt
Technol Biomed Life Sci. 1046:147–155. 2017.PubMed/NCBI View Article : Google Scholar
|
|
29
|
Ushijima M, Kunimura K and Suzuki JI:
S-1-propenylcysteine, a sulfur compound in aged garlic extract,
alleviates cold-induced reduction in peripheral blood flow in rat
via activation of the AMPK/eNOS/NO pathway. Exp Ther Med.
20:2815–2821. 2020.PubMed/NCBI View Article : Google Scholar
|
|
30
|
Kunimura K, Nakamoto M and Ushijima M:
S-1-propenylcysteine enhances endurance capacity of mice by
stimulating fatty acid metabolism via muscle isoform of carnitine
acyltransferase-1. J Nutr. 154:2707–2716. 2024.PubMed/NCBI View Article : Google Scholar
|
|
31
|
Zhang Y, Ideguchi H, Aoyagi H, Yamashiro
K, Yamamoto T, Nishibori M and Takashiba S: Malnutrition delayed
wound healing after tooth extraction by HMGB1-related prolonged
inflammation. Int Immunopharmacol. 96(107772)2021.PubMed/NCBI View Article : Google Scholar
|
|
32
|
Abe T and Hajishengallis G: Optimization
of the ligature-induced periodontitis model in mice. J Immunol
Methods. 394:49–54. 2013.PubMed/NCBI View Article : Google Scholar
|
|
33
|
Livak KJ and Schmittgen TD: Analysis of
relative gene expression data using real-time quantitative PCR and
the 2-ΔΔCT method. Methods. 25:402–408. 2001.PubMed/NCBI View Article : Google Scholar
|
|
34
|
Gadidala SK, Johny E, Thomas C, Nadella M,
Undela K and Adela R: Effect of garlic extract on markers of lipid
metabolism and inflammation in coronary artery disease (CAD)
patients: A systematic review and meta-analysis. Phytother Res.
37:2242–2254. 2023.PubMed/NCBI View Article : Google Scholar
|
|
35
|
Wlosinska M, Nilsson AC, Hlebowicz J,
Hauggaard A, Kjellin M, Fakhro M and Lindstedt S: The effect of
aged garlic extract on the atherosclerotic process - a randomized
double-blind placebo-controlled trial. BMC Complement Med Ther.
20(132)2020.PubMed/NCBI View Article : Google Scholar
|
|
36
|
Mazurek-Mochol M, Bonsmann T, Mochol M,
Poniewierska-Baran A and Pawlik A: The role of interleukin 6 in
periodontitis and its complications. Int J Mol Sci.
25(2146)2024.PubMed/NCBI View Article : Google Scholar
|
|
37
|
Takashiba S, Naruishi K and Murayama Y:
Perspective of cytokine regulation for periodontal treatment:
Fibroblast biology. J Periodontol. 74:103–110. 2003.PubMed/NCBI View Article : Google Scholar
|
|
38
|
Avendaño-Ortiz J, Redondo-Calvo FJ,
Lozano-Rodríguez R, Terrón-Arcos V, Bergón-Gutiérrez M,
Rodríguez-Jiménez C, Rodríguez JF, Del Campo R, Gómez LA,
Bejarano-Ramírez N, et al: Thiosulfinate-enriched Allium
sativum extract exhibits differential effects between healthy
and sepsis patients: The implication of HIF-1α. Int J Mol Sci.
24(6234)2023.PubMed/NCBI View Article : Google Scholar
|
|
39
|
Che HY, Zhou CH, Lyu CC, Meng Y, He YT,
Wang HQ, Wu HY, Zhang JB and Yuan B: Allicin alleviated LPS-induced
mastitis via the TLR4/NF-κB signaling pathway in bovine mammary
epithelial cells. Int J Mol Sci. 24(3805)2023.PubMed/NCBI View Article : Google Scholar
|
|
40
|
Zare E, Alirezaei A, Bakhtiyari M and
Mansouri A: Evaluating the effect of garlic extract on serum
inflammatory markers of peritoneal dialysis patients: A randomized
double-blind clinical trial study. BMC Nephrol.
20(26)2019.PubMed/NCBI View Article : Google Scholar
|
|
41
|
Zhao Z, Du Y, Yan K, Zhang L and Guo Q:
Exercise and osteoimmunology in bone remodeling. FASEB J.
38(e23554)2024.PubMed/NCBI View Article : Google Scholar
|
|
42
|
Boyce BF and Xing L: Biology of RANK,
RANKL, and osteoprotegerin. Arthritis Res Ther. 9 (Suppl
1)(S1)2007.PubMed/NCBI View
Article : Google Scholar
|
|
43
|
Takayanagi H: RANKL as the master
regulator of osteoclast differentiation. J Bone Miner Metab.
39:13–18. 2021.PubMed/NCBI View Article : Google Scholar
|
|
44
|
Marahleh A, Kitaura H, Ohori F, Kishikawa
A, Ogawa S, Shen WR, Qi J, Noguchi T, Nara Y and Mizoguchi I: TNF-α
directly enhances osteocyte RANKL expression and promotes
osteoclast formation. Front Immunol. 10(2925)2019.PubMed/NCBI View Article : Google Scholar
|
|
45
|
Sczepanik FSC, Grossi ML, Casati M,
Goldberg M, Glogauer M, Fine N and Tenenbaum HC: Periodontitis is
an inflammatory disease of oxidative stress: We should treat it
that way. Periodontol 2000. 84:45–68. 2020.PubMed/NCBI View Article : Google Scholar
|
|
46
|
Jeong YY, Ryu JH, Shin JH, Kang MJ, Kang
JR, Han J and Kang D: Comparison of anti-oxidant and
anti-inflammatory effects between fresh and aged black garlic
extracts. Molecules. 21(430)2016.PubMed/NCBI View Article : Google Scholar
|