|
1.
|
He J, Gu D, Wu X, Reynolds K, Duan X, Yao
C, Wang J, Chen CS, Chen J, Wildman RP, Klag MJ and Whelton PK:
Major causes of death among men and women in China. N Engl J Med.
353:1124–1134. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
2.
|
Fan ST, Lo CM, Liu CL, Lam CM, Yuen WK,
Yeung C and Wong J: Hepatectomy for hepatocellular carcinoma:
toward zero hospital death. Ann Surg. 229:322–330. 1999. View Article : Google Scholar : PubMed/NCBI
|
|
3.
|
Hubert C, Sempoux C, Rahier J, Horsmans Y,
Geubel A, van Beers BE, Annet L, Zech F, Leonard D and Gigot JF:
Prognostic risk factors of survival after resection of
hepatocellular carcinoma. Hepatogastroenterology. 54:1791–1797.
2007.PubMed/NCBI
|
|
4.
|
Ibrahim S, Roychowdhury A and Hean TK:
Risk factors for intrahepatic recurrence after hepatectomy for
hepatocellular carcinoma. Am J Surg. 194:17–22. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
5.
|
Mann CD, Neal CP, Garcea G, Manson MM,
Dennison AR and Berry DP: Prognostic molecular markers in
hepatocellular carcinoma: a systematic review. Eur J Cancer.
43:979–992. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
6.
|
Murray CJ and Lopez AD: Mortality by cause
for eight regions of the world: global burden of disease study.
Lancet. 349:1269–1276. 1997. View Article : Google Scholar
|
|
7.
|
Giannelli G and Antonaci S: Novel concepts
in hepatocellular carcinoma: from molecular research to clinical
practice. J Clin Gastroenterol. 40:842–846. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
8.
|
Yang LY, Tao YM, Ou DP, Wang W, Chang ZG
and Wu F: Increased expression of Wiskott-Aldrich syndrome protein
family verprolin-homologous protein 2 correlated with poor
prognosis of hepatocellular carcinoma. Clin Cancer Res.
12:5673–5679. 2006. View Article : Google Scholar
|
|
9.
|
Farinati F, Rinaldi M, Gianni S and
Naccarato R: How should patients with hepatocellular carcinoma be
staged? Validation of a new prognostic system. Cancer.
89:2266–2273. 2000. View Article : Google Scholar : PubMed/NCBI
|
|
10.
|
Wong CC, Wong CM, Au SL and Ng IO:
RhoGTPases and Rho-effectors in hepatocellular carcinoma
metastasis: ROCK N'Rho move it. Liver Int. 30:642–656.
2010.PubMed/NCBI
|
|
11.
|
Chae S, Jun HO, Lee EG, Yang SJ, Lee DC,
Jung JK, Park KC, Yeom YI and Kim KW: Osteopontin splice variants
differentially modulate the migratory activity of hepatocellular
carcinoma cell lines. Int J Oncol. 35:1409–1416. 2009.PubMed/NCBI
|
|
12.
|
Feng H, Zhang J, Li X and Chen WN:
HBX-mediated migration of HBV-replicating HepG2 cells: insights on
development of hepatocellular carcinoma. J Biomed Biotechnol. Sep.
16–2009.(Epub ahead of print).
|
|
13.
|
Grise F, Bidaud A and Moreau V: Rho
GTPases in hepatocellular carcinoma. Biochim Biophys Acta.
1795:137–151. 2009.PubMed/NCBI
|
|
14.
|
Fukui K, Tamura S, Wada A, Kamada Y, Sawai
Y, Imanaka K, Kudara T, Shimomura I and Hayashi N: Expression and
prognostic role of RhoA GTPases in hepatocellular carcinoma. J
Cancer Res Clin Oncol. 132:627–633. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
15.
|
Carmona-Cuenca I, Roncero C, Sancho P,
Caja L, Fausto N and Fernández M: Upregulation of the NADPH oxidase
NOX4 by TGF-beta in hepatocytes is required for its pro-apoptotic
activity. J Hepatol. 49:965–976. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
16.
|
Lee TK, Poon RT, Yuen AP, Man K, Yang ZF,
Guan XY and Fan ST: Significance of the Rac signaling pathway in
HCC cell motility: implications for a new therapeutic target.
Carcinogenesis. 26:681–687. 2005.PubMed/NCBI
|
|
17.
|
Hiramoto K, Negishi M and Katoh H: Dock4
is regulated by RhoG and promotes Rac-dependent cell migration. Exp
Cell Res. 312:4205–4216. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
18.
|
Epting D, Wendik B, Bennewitz K, Dietz CT,
Driever W and Kroll J: The Rac1 regulator ELMO1 controls vascular
morphogenesis in zebrafish. Circ Res. 107:45–55. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
19.
|
Hope H, Schmauch C, Arkowitz RA and
Bassilana M: The Candida albicans ELMO homologue functions
together with Rac1 and Dck1, upstream of the MAP Kinase Cek1, in
invasive filamentous growth. Mol Microbiol. 76:1572–1590. 2007.
|
|
20.
|
Komander D, Patel M, Laurin M, Fradet N,
Pelletier A and Barford D: An alpha-helical extension of the ELMO1
pleckstrin homology domain mediates direct interaction to DOCK180
and is critical in Rac signaling. Mol Biol Cell. 19:483748–483751.
2008. View Article : Google Scholar : PubMed/NCBI
|
|
21.
|
Bouschet T, Martin S, Kanamarlapudi V,
Mundell S and Henley JM: The calcium-sensing receptor changes cell
shape via a beta-arrestin-1 ARNO ARF 6 ELMO protein network. J Cell
Sci. 120:2489–2497. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
22.
|
Ip WK, Lai PB, Wong NL, Sy SM, Beheshti B,
Squire JA and Wong N: Identification of PEG10 as a progression
related biomarker for hepatocellular carcinoma. Cancer Lett.
250:284–291. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
23.
|
Shimazaki A, Tanaka Y, Shinosaki T, Ikeda
M, Watada H, Hirose T, Kawamori R and Maeda S: ELMO1 increases
expression of extracellular matrix proteins and inhibits cell
adhesion to ECMs. Kidney Int. 70:1769–1776. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
24.
|
Jarzynka MJ, Hu B, Hui KM, Bar-Joseph I,
Gu W, Hirose T, Haney LB, Ravichandran KS, Nishikawa R and Cheng
SY: ELMO1 and Dock180, a bipartite Rac1 guanine nucleotide exchange
factor, promote human glioma cell invasion. Cancer Res.
67:7203–7211. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
25.
|
Hsu SC, Kuo CL, Lin JP, Lee JH, Lin CC, Su
CC, Yang MD and Chung JG: Crude extracts of Euchresta
formosana radix inhibit invasion and migration of human
hepatocellular carcinoma cells. Anticancer Res. 27:2377–2384.
2007.
|
|
26.
|
Wong CC, Wong CM, Ko FC, Chan LK, Ching YP
and Yam JW: Deleted in liver cancer 1 (DLC1) negatively regulates
Rho/ROCK/MLC pathway in hepatocellular carcinoma. PLoS One.
23:E27792008. View Article : Google Scholar : PubMed/NCBI
|
|
27.
|
Tian J, Tang ZY, Ye SL, Liu YK, Lin ZY,
Chen J and Xue Q: New human hepatocellular carcinoma (HCC) cell
line with highly metastatic potential (MHCC97) and its expressions
of the factors associated with metastasis. Br J Cancer. 81:814–821.
1999. View Article : Google Scholar : PubMed/NCBI
|
|
28.
|
Zhang SZ, Pan FY, Xu JF, Yuan J, Guo SY,
Dai G, Xue B, Shen WG, Wen CJ, Zhao DH and Li CJ: Knockdown of
c-Met by adenovirus-delivered small interfering RNA inhibits
hepatocellular carcinoma growth in vitro and in vivo.
Mol Cancer Ther. 4:1577–1584. 2005. View Article : Google Scholar : PubMed/NCBI
|
