Detection of circulating tumor cells: Clinical relevance of a novel metastatic tumor marker (Review)

  • Authors:
    • Chuanli Ren
    • Chongxu Han
    • Daxin Wang
    • Xiaohang Zhao
    • Guangfu Jin
    • Hongbing Shen
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  • Published online on: March 21, 2011     https://doi.org/10.3892/etm.2011.234
  • Pages: 385-391
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Abstract

Most cancer-related deaths are caused by the hematogenous spread of cancer cells to distant organs and their subsequent metastasis. During the early stages of the metastatic cascade, cancer cells disseminate from the primary site via the lymphatic vessels and/or by hematogenous routes. Circulating tumor cells (CTCs), cancer cells that have disseminated into the systemic circulation, may be a predictor of poor prognosis in several carcinomas. An understanding of the molecular mechanisms involved in the blood-borne dissemination of cancer cells may help to clarify the process of metastasis and provide a powerful and non-invasive approach for anticancer treatments that are tailored to individual patients.
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May-June 2011
Volume 2 Issue 3

Print ISSN: 1792-0981
Online ISSN:1792-1015

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Copy and paste a formatted citation
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Spandidos Publications style
Ren C, Han C, Wang D, Zhao X, Jin G and Shen H: Detection of circulating tumor cells: Clinical relevance of a novel metastatic tumor marker (Review). Exp Ther Med 2: 385-391, 2011
APA
Ren, C., Han, C., Wang, D., Zhao, X., Jin, G., & Shen, H. (2011). Detection of circulating tumor cells: Clinical relevance of a novel metastatic tumor marker (Review). Experimental and Therapeutic Medicine, 2, 385-391. https://doi.org/10.3892/etm.2011.234
MLA
Ren, C., Han, C., Wang, D., Zhao, X., Jin, G., Shen, H."Detection of circulating tumor cells: Clinical relevance of a novel metastatic tumor marker (Review)". Experimental and Therapeutic Medicine 2.3 (2011): 385-391.
Chicago
Ren, C., Han, C., Wang, D., Zhao, X., Jin, G., Shen, H."Detection of circulating tumor cells: Clinical relevance of a novel metastatic tumor marker (Review)". Experimental and Therapeutic Medicine 2, no. 3 (2011): 385-391. https://doi.org/10.3892/etm.2011.234