1
|
Angulo P: Nonalcoholic fatty liver
disease. N Engl J Med. 346:1221–1231. 2002. View Article : Google Scholar : PubMed/NCBI
|
2
|
Fabbrini E, Sullivan S and Klein S:
Obesity and nonalcoholic fatty liver disease: biochemical,
metabolic, and clinical implications. Hepatology. 51:679–689. 2010.
View Article : Google Scholar : PubMed/NCBI
|
3
|
Tiniakos DG, Vos MB and Brunt EM:
Nonalcoholic fatty liver disease: pathology and pathogenesis. Annu
Rev Pathol. 5:145–171. 2010. View Article : Google Scholar : PubMed/NCBI
|
4
|
Jaworski K, Sarkadi-Nagy E, Duncan RE,
Ahmadian M and Sul HS: Regulation of triglyceride metabolism. IV.
Hormonal regulation of lipolysis in adipose tissue. Am J Physiol
Gastrointest Liver Physiol. 293:G1–G4. 2007. View Article : Google Scholar : PubMed/NCBI
|
5
|
Iizuka K and Horikawa Y: ChREBP: a
glucose-activated transcription factor involved in the development
of metabolic syndrome. Endocr J. 55:617–624. 2008. View Article : Google Scholar : PubMed/NCBI
|
6
|
Higuchi N, Kato M, Shundo Y, Tajiri H,
Tanaka M, Yamashita N, Kohjima M, Kotoh K, Nakamuta M, Takayanagi R
and Enjoji M: Liver X receptor in cooperation with SREBP-1c is a
major lipid synthesis regulator in nonalcoholic fatty liver
disease. Hepatol Res. 38:1122–1129. 2008. View Article : Google Scholar : PubMed/NCBI
|
7
|
Kato M, Higuchi N and Enjoji M: Reduced
hepatic expression of adipose tissue triglyceride lipase and CGI-58
may contribute to the development of non-alcoholic fatty liver
disease in patients with insulin resistance. Scand J Gastroenterol.
43:1018–1019. 2008. View Article : Google Scholar
|
8
|
Meshkani R and Adeli K: Hepatic insulin
resistance, metabolic syndrome and cardiovascular disease. Clin
Biochem. 42:1331–1346. 2009. View Article : Google Scholar : PubMed/NCBI
|
9
|
Shelness GS and Sellers JA:
Very-low-density lipoprotein assembly and secretion. Curr Opin
Lipidol. 12:151–157. 2001. View Article : Google Scholar : PubMed/NCBI
|
10
|
Sparks JD and Sparks CE: Overindulgence
and metabolic syndrome: is FoxO1 a missing link? J Clin Invest.
118:2012–2015. 2008.PubMed/NCBI
|
11
|
Raabe M, Veniant MM, Sullivan MA, Zlot CH,
Bjorkegren J, Nielsen LB, Wong JS, Hamilton RL and Young SG:
Analysis of the role of microsomal triglyceride transfer protein in
the liver of tissue-specific knockout mice. J Clin Invest.
103:1287–1298. 1999. View
Article : Google Scholar : PubMed/NCBI
|
12
|
Binas B and Erol E: FABPs as determinants
of myocellular and hepatic fuel metabolism. Mol Cell Biochem.
299:75–84. 2007. View Article : Google Scholar : PubMed/NCBI
|
13
|
Sladek FM: Orphan receptor HNF-4 and
liver-specific gene expression. Receptor. 3:223–232.
1993.PubMed/NCBI
|
14
|
Sheena V, Hertz R, Nousbeck J, Berman I,
Magenheim J and Bar-Tana J: Transcriptional regulation of human
microsomal triglyceride transfer protein by hepatocyte nuclear
factor-4alpha. J Lipid Res. 46:328–341. 2005. View Article : Google Scholar : PubMed/NCBI
|
15
|
Ladias JA, Hadzopoulou-Cladaras M,
Kardassis D, Cardot P, Cheng J, Zannis V and Cladaras C:
Transcriptional regulation of human apolipoprotein genes ApoB,
ApoCIII, and ApoAII by members of the steroid hormone receptor
superfamily HNF-4, ARP-1, EAR-2, and EAR-3. J Biol Chem.
267:15849–15860. 1992.
|
16
|
Hertz R, Magenheim J, Berman I and
Bar-Tana J: Fatty acyl-CoA thioesters are ligands of hepatic
nuclear factor-4alpha. Nature. 392:512–516. 1998. View Article : Google Scholar : PubMed/NCBI
|
17
|
Jump DB: Dietary polyunsaturated fatty
acids and regulation of gene transcription. Curr Opin Lipidol.
13:155–164. 2002. View Article : Google Scholar : PubMed/NCBI
|
18
|
Yoon M: The role of PPARalpha in lipid
metabolism and obesity: focusing on the effects of estrogen on
PPARalpha actions. Pharmacol Res. 60:151–159. 2009. View Article : Google Scholar : PubMed/NCBI
|
19
|
Ameen C, Edvardsson U, Ljungberg A, Asp L,
Akerblad P, Tuneld A, Olofsson SO, Linden D and Oscarsson J:
Activation of peroxisome proliferator-activated receptor alpha
increases the expression and activity of microsomal triglyceride
transfer protein in the liver. J Biol Chem. 280:1224–1229. 2005.
View Article : Google Scholar
|
20
|
Landrier JF, Thomas C, Grober J, Duez H,
Percevault F, Souidi M, Linard C, Staels B and Besnard P: Statin
induction of liver fatty acid-binding protein (L-FABP) gene
expression is peroxisome proliferator-activated
receptor-alpha-dependent. J Biol Chem. 279:45512–45518. 2004.
View Article : Google Scholar : PubMed/NCBI
|
21
|
Au WS, Kung HF and Lin MC: Regulation of
microsomal triglyceride transfer protein gene by insulin in HepG2
cells: roles of MAPKerk and MAPKp38. Diabetes. 52:1073–1080. 2003.
View Article : Google Scholar : PubMed/NCBI
|
22
|
Kamagate A, Qu S, Perdomo G, Su D, Kim DH,
Slusher S, Meseck M and Dong HH: FoxO1 mediates insulin-dependent
regulation of hepatic VLDL production in mice. J Clin Invest.
118:2347–2364. 2008.PubMed/NCBI
|
23
|
Wei Y, Wang D, Topczewski F and
Pagliassotti MJ: Saturated fatty acids induce endoplasmic reticulum
stress and apoptosis independently of ceramide in liver cells. Am J
Physiol Endocrinol Metab. 291:E275–E281. 2006. View Article : Google Scholar : PubMed/NCBI
|
24
|
Roebuck KA: Oxidant stress regulation of
IL-8 and ICAM-1 gene expression: differential activation and
binding of the transcription factors AP-1 and NF-κB (Review). Int J
Mol Med. 4:223–230. 1999.PubMed/NCBI
|
25
|
Gius D, Botero A, Shah S and Curry HA:
Intracellular oxidation/reduction status in the regulation of
transcription factors NF-kappaB and AP-1. Toxicol Lett. 106:93–106.
1999. View Article : Google Scholar : PubMed/NCBI
|
26
|
Liu H, Colavitti R, Rovira II and Finkel
T: Redox-dependent transcriptional regulation. Circ Res.
97:967–974. 2005. View Article : Google Scholar : PubMed/NCBI
|
27
|
George DK, Goldwurm S, MacDonald GA,
Cowley LL, Walker NI, Ward PJ, Jazwinska EC and Powell LW:
Increased hepatic iron concentration in nonalcoholic
steatohepatitis is associated with increased fibrosis.
Gastroenterology. 114:311–318. 1998. View Article : Google Scholar : PubMed/NCBI
|
28
|
Mantena SK, King AL, Andringa KK,
Eccleston HB and Bailey SM: Mitochondrial dysfunction and oxidative
stress in the pathogenesis of alcohol- and obesity-induced fatty
liver diseases. Free Radic Biol Med. 44:1259–1272. 2008. View Article : Google Scholar : PubMed/NCBI
|
29
|
Mitsuyoshi H, Yasui K, Harano Y, Endo M,
Tsuji K, Minami M, Itoh Y, Okanoue T and Yoshikawa T: Analysis of
hepatic genes involved in the metabolism of fatty acids and iron in
nonalcoholic fatty liver disease. Hepatol Res. 39:366–373. 2009.
View Article : Google Scholar : PubMed/NCBI
|