1.
|
Martin AM, Blackwood MA, Antin-Ozerkis D,
et al: Germline mutations in BRCA1 and BRCA2 in
breast-ovarian families from a breast cancer risk evaluation
clinic. J Clin Oncol. 19:2247–2253. 2001.
|
2.
|
Parkin DM, Bray F, Ferlay J and Pisani P:
Global cancer statistics, 2002. CA Cancer J Clin. 55:74–108. 2005.
View Article : Google Scholar
|
3.
|
Cancer Incidence Data: Sri Lanka Year
2001–2005. Cancer Registry, National Cancer Control Programme;
Colombo 5, Sri Lanka: 2009
|
4.
|
Parkin DM, Whelan SL, Ferlay J, Teppo L
and Thomas DB: Cancer Incidence in Five Continents. VIII. IARC
Scientific Publications no. 143. IARC; Lyon: 1997
|
5.
|
Liede A and Narod SA: Hereditary breast
and ovarian cancer in Asia: genetic epidemiology of BRCA1
and BRCA2. Hum Mutat. 20:413–424. 2002. View Article : Google Scholar : PubMed/NCBI
|
6.
|
Newman B, Austin MA, Lee M and King MC:
Inheritance of human breast cancer: evidence for autosomal dominant
transmission in high risk families. Proc Natl Acad Sci USA.
85:3044–3048. 1988. View Article : Google Scholar : PubMed/NCBI
|
7.
|
Fackenthal JD and Olopade OI: Breast
cancer risk associated with BRCA1 and BRCA2 in
diverse populations. Nat Rev Cancer. 7:937–948. 2007. View Article : Google Scholar
|
8.
|
Satagopan JM, Offit K, Foulkes W, et al:
The lifetime risks of breast cancer in Ashkenazi Jewish carriers of
BRCA1 and BRCA2 mutations. Cancer Epidemiol
Biomarkers Prev. 10:467–473. 2001.PubMed/NCBI
|
9.
|
Antoniou A, Pharoah PDP, Narod S, et al:
Average risks of breast and ovarian cancer associated with
BRCA1 or BRCA2 mutations detected in case series
unselected for family history: a combined analysis of 22 studies.
Am J Hum Genet. 72:1117–1130. 2003.PubMed/NCBI
|
10.
|
Lahad EL and Friedman E: Cancer risks
among BRCA1 and BRCA2 mutation carriers. Br J Cancer.
96:11–15. 2007. View Article : Google Scholar
|
11.
|
Hall JM, Lee MK, Newman B, Morrow JE,
Anderson LA, Huey B and King MC: Linkage of early-onset familial
breast cancer to chromosome 17q21. Science. 250:1684–1689. 1990.
View Article : Google Scholar : PubMed/NCBI
|
12.
|
Wooster R, Neuhausen SL, Mangion J, et al:
Localization of a breast cancer susceptibility gene, BRCA2,
to chromosome 13q12–13. Science. 265:2088–2090. 1994. View Article : Google Scholar : PubMed/NCBI
|
13.
|
Narod SA and Foulkes WD: BRCA1 and
BRCA2: 1994 and beyond. Nat Rev Cancer. 4:665–676. 2004.
View Article : Google Scholar
|
14.
|
Scully R and Livingston DM: In search of
the tumour-suppressor function of BRCA1 and BRCA2.
Nature. 408:429–432. 2000. View
Article : Google Scholar : PubMed/NCBI
|
15.
|
Venkitaraman AR: Cancer susceptibility and
the functions of BRCA1 and BRCA2. Cell. 108:171–182.
2002. View Article : Google Scholar : PubMed/NCBI
|
16.
|
De Silva W, Karunanayake EH, Tennekoon KH,
Allen M, Amarasinghe I, Angunawala P and Ziard MH: Novel sequence
variants and a high frequency of recurrent polymorphisms in
BRCA1 gene in Sri Lankan breast cancer patients and at risk
individuals. BMC Cancer. 8:2142008.PubMed/NCBI
|
17.
|
Ford D, Easton DF, Stratton M, et al:
Genetic heterogeneity and penetrance analysis of the BRCA1
and BRCA2 genes in breast cancer families. The Breast Cancer
Linkage Consortium. Am J Hum Genet. 62:676–689. 1998. View Article : Google Scholar : PubMed/NCBI
|
18.
|
Thompson D and Easton D: Variation in
cancer risks, by mutation position, in BRCA2 mutation
carriers. Am J Hum Genet. 68:410–419. 2001. View Article : Google Scholar : PubMed/NCBI
|
19.
|
Liede A, Karlan BY and Narod SA: Cancer
risks for male carriers of germline mutations in BRCA1 and
BRCA2: a review of the literature. J Clin Oncol. 22:735–742.
2004. View Article : Google Scholar : PubMed/NCBI
|
20.
|
Ferla R, Calo V, Cascio S, et al: Founder
mutations in BRCA1 and BRCA2 genes. Ann Oncol.
18(Supp 6): S93–S98. 2007. View Article : Google Scholar
|
21.
|
Miller SA, Dykes DD and Poleskey HF: A
simple salting out procedure for extracting DNA from human
nucleated cells. Nucleic Acids Res. 16:12151988. View Article : Google Scholar : PubMed/NCBI
|
22.
|
Rozen S and Skaletsky HJ: Primer3, 1996.
Code available at http://www-genome.wi.mit.edu/genome_software/other/primer3.htmluri.
|
23.
|
Wallace AJ: SSCP/Heteroduplex analysis.
PCR Mutation Detection Protocols. 187. Theophilus BDM and Rapley R:
Humana Press; Totowa, New Jersey: pp. 151–163. 2002, View Article : Google Scholar : PubMed/NCBI
|
24.
|
Desmet FO, Hamroun D, Lalande M,
Collod-Béroud G, Claustres M and Béroud C: Human Splicing Finder:
an online bioinformatics tool to predict splicing signals. Nucleic
Acid Res. 37:e672009. View Article : Google Scholar : PubMed/NCBI
|
25.
|
Bork P, Blomberg N and Nilges M: Internal
repeats in BRCA2 protein sequence. Nat Genet. 13:22–23. 1996.
View Article : Google Scholar
|
26.
|
Lord CJ and Ashworth A: RAD51,
BRCA2 and DNA repair: a partial resolution. Nat Struct Mol
Biol. 14:461–462. 2007.
|
27.
|
Vreeswijk MPG, Kraan JN, van der Klift HM,
et al: Intronic variants in BRCA1 and BRCA2 that
affect RNA splicing can be reliably selected by splice-site
prediction programs. Hum Mutat. 30:107–114. 2009.
|
28.
|
Breast Cancer Information Core (BIC)
Database: Available at: http://research.nhgri.nih.gov/bic/uri.
Last modified: Wednesday, 29 September 2010.
|
29.
|
Fuks F, Milner J and Kouzarides T:
BRCA2 associates with acetyltransferase activity when bound
to P/CAF. Oncogene. 17:2351–2354. 1998. View Article : Google Scholar
|
30.
|
Healey CS, Dunning AM, Teare MD, et al: A
common variant in BRCA2 is associated with both breast
cancer risk and prenatal viability. Nat Genet. 26:362–364. 2000.
View Article : Google Scholar
|
31.
|
Spurdle AB, Hopperm JL, Chen X, et al: The
BRCA2 372 HH genotype is associated with risk of breast
cancer in Australian women under age 60 years. Cancer Epidemiol
Biomarkers Prev. 11:413–416. 2002.PubMed/NCBI
|
32.
|
Cox DG, Hankinson SE and Hunter DJ: No
association between BRCA2 N372H and breast cancer risk.
Cancer Epidemiol Biomarkers Prev. 14:1353–1354. 2005.
|
33.
|
Toh GT, Kang P, Lee SSW, et al:
BRCA1 and BRCA2 germline mutations in Malaysian women
with early onset breast cancer without a family history. PLoS One.
3:e20242008. View Article : Google Scholar : PubMed/NCBI
|
34.
|
Qiu LX, Yao L, Xue K, et al: BRCA2
N372H polymorphism and breast cancer susceptibility: a
meta-analysis involving 44,903 study participants. Breast Cancer
Res Treat. 123:487–490. 2010. View Article : Google Scholar
|
35.
|
Ikeda N, Miyoshi Y, Yoned K, Shiba E,
Sekihara Y, Kinoshita M and Noguchi S: Frequency of BRCA1
and BRCA2 germline mutations in Japanese breast cancer
families. Int J Cancer. 91:83–88. 2001.
|
36.
|
Saxena S, Chakraborthy A, Kaushal M, et
al: Contribution of germline BRCA1 and BRCA2 sequence
alterations to breast cancer in Northern India. BMC Med Genet.
7:752006. View Article : Google Scholar
|