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Article

TEM observation of ultrasound-induced mitophagy in nasopharyngeal carcinoma cells in the presence of curcumin

  • Authors:
    • Xinna Wang
    • Albert Wingnang Leung
    • Jianmei Luo
    • Chuanshan Xu
  • View Affiliations / Copyright

    Affiliations: Department of Ultrasound, The Affiliated Hospital, Xi'an Medical University, Xi'an, P.R. China, School of Chinese Medicine, The Chinese University of Hong Kong, Shatin, Hong Kong SAR, P.R. China
  • Pages: 146-148
    |
    Published online on: October 13, 2011
       https://doi.org/10.3892/etm.2011.365
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Abstract

The present study was designed to observe the initiation of mitophagy in tumor cells after ultrasound treatment in the presence of curcumin under transmission electron microscopy. Nasopharyngeal carcinoma CNE2 cells were incubated with 10 µM curcumin and then exposed to ultrasound for 8 sec at an intensity of 0.46 W/cm2. Severely swollen mitochondria, disrupted mitochondria and mitophagy were noted in the CNE2 cells after ultrasound treatment in the presence of curcumin. Our findings demonstrated that ultrasound treatment in the presence of curcumin significantly initiated mitophagy in CNE2 cells, which suggests that mitophagy serves as an important event in the process of cell death of nasopharyngeal carcinoma cells.
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Copy and paste a formatted citation
Spandidos Publications style
Wang X, Leung AW, Luo J and Xu C: TEM observation of ultrasound-induced mitophagy in nasopharyngeal carcinoma cells in the presence of curcumin. Exp Ther Med 3: 146-148, 2012.
APA
Wang, X., Leung, A.W., Luo, J., & Xu, C. (2012). TEM observation of ultrasound-induced mitophagy in nasopharyngeal carcinoma cells in the presence of curcumin. Experimental and Therapeutic Medicine, 3, 146-148. https://doi.org/10.3892/etm.2011.365
MLA
Wang, X., Leung, A. W., Luo, J., Xu, C."TEM observation of ultrasound-induced mitophagy in nasopharyngeal carcinoma cells in the presence of curcumin". Experimental and Therapeutic Medicine 3.1 (2012): 146-148.
Chicago
Wang, X., Leung, A. W., Luo, J., Xu, C."TEM observation of ultrasound-induced mitophagy in nasopharyngeal carcinoma cells in the presence of curcumin". Experimental and Therapeutic Medicine 3, no. 1 (2012): 146-148. https://doi.org/10.3892/etm.2011.365
Copy and paste a formatted citation
x
Spandidos Publications style
Wang X, Leung AW, Luo J and Xu C: TEM observation of ultrasound-induced mitophagy in nasopharyngeal carcinoma cells in the presence of curcumin. Exp Ther Med 3: 146-148, 2012.
APA
Wang, X., Leung, A.W., Luo, J., & Xu, C. (2012). TEM observation of ultrasound-induced mitophagy in nasopharyngeal carcinoma cells in the presence of curcumin. Experimental and Therapeutic Medicine, 3, 146-148. https://doi.org/10.3892/etm.2011.365
MLA
Wang, X., Leung, A. W., Luo, J., Xu, C."TEM observation of ultrasound-induced mitophagy in nasopharyngeal carcinoma cells in the presence of curcumin". Experimental and Therapeutic Medicine 3.1 (2012): 146-148.
Chicago
Wang, X., Leung, A. W., Luo, J., Xu, C."TEM observation of ultrasound-induced mitophagy in nasopharyngeal carcinoma cells in the presence of curcumin". Experimental and Therapeutic Medicine 3, no. 1 (2012): 146-148. https://doi.org/10.3892/etm.2011.365
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