Secondary prevention of stroke: Pleiotropic effects of optimal oral pharmacotherapy (Review)

  • Authors:
    • Kiyoshi Kikuchi
    • Ko-Ichi Kawahara
    • Naoki Miura
    • Takashi Ito
    • Yoko Morimoto
    • Salunya Tancharoen
    • Nobuyuki Takeshige
    • Hisaaki Uchikado
    • Rokudai Sakamoto
    • Naohisa Miyagi
    • Chiemi Kikuchi
    • Narumi Iida
    • Naoto Shiomi
    • Terukazu Kuramoto
    • Masaru Hirohata
    • Ikuro Maruyama
    • Motohiro Morioka
    • Eiichiro Tanaka
  • View Affiliations

  • Published online on: April 24, 2012     https://doi.org/10.3892/etm.2012.560
  • Pages: 3-7
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Abstract

Stroke is a major cause of mortality and disability worldwide. During the past three decades, major advances have occurred in secondary prevention, which have demonstrated the broader potential for the prevention of stroke. Risk factors for stroke include previous stroke or transient ischemic attack, hypertension, high blood cholesterol and diabetes. Proven secondary prevention strategies are antiplatelet agents, antihypertensive drugs, statins and glycemic control. In the present review, we evaluated the secondary prevention of stroke in light of clinical studies and discuss new pleiotropic effects beyond the original effects and emerging clinical evidence, with a focus on the effect of optimal oral pharmacotherapy.
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July 2012
Volume 4 Issue 1

Print ISSN: 1792-0981
Online ISSN:1792-1015

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Copy and paste a formatted citation
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Spandidos Publications style
Kikuchi K, Kawahara K, Miura N, Ito T, Morimoto Y, Tancharoen S, Takeshige N, Uchikado H, Sakamoto R, Miyagi N, Miyagi N, et al: Secondary prevention of stroke: Pleiotropic effects of optimal oral pharmacotherapy (Review). Exp Ther Med 4: 3-7, 2012.
APA
Kikuchi, K., Kawahara, K., Miura, N., Ito, T., Morimoto, Y., Tancharoen, S. ... Tanaka, E. (2012). Secondary prevention of stroke: Pleiotropic effects of optimal oral pharmacotherapy (Review). Experimental and Therapeutic Medicine, 4, 3-7. https://doi.org/10.3892/etm.2012.560
MLA
Kikuchi, K., Kawahara, K., Miura, N., Ito, T., Morimoto, Y., Tancharoen, S., Takeshige, N., Uchikado, H., Sakamoto, R., Miyagi, N., Kikuchi, C., Iida, N., Shiomi, N., Kuramoto, T., Hirohata, M., Maruyama, I., Morioka, M., Tanaka, E."Secondary prevention of stroke: Pleiotropic effects of optimal oral pharmacotherapy (Review)". Experimental and Therapeutic Medicine 4.1 (2012): 3-7.
Chicago
Kikuchi, K., Kawahara, K., Miura, N., Ito, T., Morimoto, Y., Tancharoen, S., Takeshige, N., Uchikado, H., Sakamoto, R., Miyagi, N., Kikuchi, C., Iida, N., Shiomi, N., Kuramoto, T., Hirohata, M., Maruyama, I., Morioka, M., Tanaka, E."Secondary prevention of stroke: Pleiotropic effects of optimal oral pharmacotherapy (Review)". Experimental and Therapeutic Medicine 4, no. 1 (2012): 3-7. https://doi.org/10.3892/etm.2012.560