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Article

Endoluminal treatment for venous vascular complications of malignant tumors

  • Authors:
    • Liang Xiao
    • Jia-Jie Tong
    • Jing Shen
  • View Affiliations / Copyright

    Affiliations: Department of Radiology, First Hospital of China Medical University, Shenyang, Liaoning 110001, P.R. China
  • Pages: 323-328
    |
    Published online on: May 24, 2012
       https://doi.org/10.3892/etm.2012.589
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Abstract

The aim of this study was to explore the efficacy and safety of interventional treatment for venous vascular complications of malignant tumors. Sixty-one patients with venous vascular complications of malignant tumors were treated from May 2002 to May 2009; 37 men and 24 women with mean age 57.8 years (33-82 years). Lesions included acute deep vein thrombosis (n=18); venous stenosis or occlusion (n=32); tumor embolus in vein (n=11). The interventional therapeutic operations included vena cava filter implantation, transcatheter thrombolytic therapy, recanalization, percutaneous transluminal angioplasty (PTA) and stenting. The success rate of thrombolysis and stent implantation, the clinical success rate, complications, recurrence rate of the treated region and survival duration were recorded. Eighteen patients accepted filter and thrombolytic therapy with a success rate of 100%; total urokinase dosage was 7.42±1.49 (4.5-10) million units. Symptoms disappeared (n=15), were palliated (n=3) and thrombi were completely dissolved (n=2), almost completely dissolved (n=8, >90%), partially dissolved (n=6, 50-90%) and not dissolved (n=2, <50%). No pulmonary embolism emerged after the operation. Forty-three patients accepted recanalization, PTA and stent therapy with a success rate of 95.3% (41/43). Symptoms disappeared (n=25), were palliated (n=16) and did not change (n=2) 3 days following the operation. There were no severe complications during the procedure. During follow-up, 12 patients again suffered symptoms of venous occlusion and 47 patients died of tumor aggravation without symptom recurrence. As a result, interventional therapy has advantages including smaller injuries, well tolerance, high success rate, quick palliation of symptoms and superior clinical efficacy in the treatment of venous vascular complications for malignant tumors.
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Copy and paste a formatted citation
Spandidos Publications style
Xiao L, Tong J and Shen J: Endoluminal treatment for venous vascular complications of malignant tumors. Exp Ther Med 4: 323-328, 2012.
APA
Xiao, L., Tong, J., & Shen, J. (2012). Endoluminal treatment for venous vascular complications of malignant tumors. Experimental and Therapeutic Medicine, 4, 323-328. https://doi.org/10.3892/etm.2012.589
MLA
Xiao, L., Tong, J., Shen, J."Endoluminal treatment for venous vascular complications of malignant tumors". Experimental and Therapeutic Medicine 4.2 (2012): 323-328.
Chicago
Xiao, L., Tong, J., Shen, J."Endoluminal treatment for venous vascular complications of malignant tumors". Experimental and Therapeutic Medicine 4, no. 2 (2012): 323-328. https://doi.org/10.3892/etm.2012.589
Copy and paste a formatted citation
x
Spandidos Publications style
Xiao L, Tong J and Shen J: Endoluminal treatment for venous vascular complications of malignant tumors. Exp Ther Med 4: 323-328, 2012.
APA
Xiao, L., Tong, J., & Shen, J. (2012). Endoluminal treatment for venous vascular complications of malignant tumors. Experimental and Therapeutic Medicine, 4, 323-328. https://doi.org/10.3892/etm.2012.589
MLA
Xiao, L., Tong, J., Shen, J."Endoluminal treatment for venous vascular complications of malignant tumors". Experimental and Therapeutic Medicine 4.2 (2012): 323-328.
Chicago
Xiao, L., Tong, J., Shen, J."Endoluminal treatment for venous vascular complications of malignant tumors". Experimental and Therapeutic Medicine 4, no. 2 (2012): 323-328. https://doi.org/10.3892/etm.2012.589
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