The prognostic value of copeptin for acute intracerebral hemorrhage patients

  • Authors:
    • Aimei Zhang
    • Jun Li
    • Xiaoyun Li
    • Li Song
    • Hongfang Li
  • View Affiliations

  • Published online on: November 7, 2012     https://doi.org/10.3892/etm.2012.804
  • Pages: 467-470
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Abstract

The aim of the current study was to examine the prognostic value of copeptin for acute intracerebral hemorrhage (ICH) patients. A total of 120 patients were recruited. The plasma copeptin levels were measured using sandwich immunoassays. The hematoma volume, Glasgow coma scale (GCS) and ICH score were evaluated. The 90-day functional outcomes were measured with the modified Rankin scale (mRS). Copeptin correlated positively with hematoma volume (r=0.61, P=0.000), Hemphill scores (r=0.78, P=0.000) and white blood cell counts (r=0.58, P=0.000), whereas copeptin correlated negatively with GCS scores (r=-0.79, P=0.000). Copeptin levels were also higher in patients with an unfavorable functional outcome at 90 days than in patients with a favorable outcome (4.14±0.87 vs. 3.09±0.30 ng/ml; t=8.001, P=0.00). Monovariate logistic regression analysis results suggest that copeptin is a predictor of the 90-day functional outcomes of ICH patients (OR=3.17, 95% CI 2.01-4.35, P=0.003. Multivariate logistic regression analysis results indicate that copeptin is an independent predictor of the 90-day functional outcomes of ICH patients.
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February 2013
Volume 5 Issue 2

Print ISSN: 1792-0981
Online ISSN:1792-1015

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Spandidos Publications style
Zhang A, Li J, Li X, Song L and Li H: The prognostic value of copeptin for acute intracerebral hemorrhage patients. Exp Ther Med 5: 467-470, 2013
APA
Zhang, A., Li, J., Li, X., Song, L., & Li, H. (2013). The prognostic value of copeptin for acute intracerebral hemorrhage patients. Experimental and Therapeutic Medicine, 5, 467-470. https://doi.org/10.3892/etm.2012.804
MLA
Zhang, A., Li, J., Li, X., Song, L., Li, H."The prognostic value of copeptin for acute intracerebral hemorrhage patients". Experimental and Therapeutic Medicine 5.2 (2013): 467-470.
Chicago
Zhang, A., Li, J., Li, X., Song, L., Li, H."The prognostic value of copeptin for acute intracerebral hemorrhage patients". Experimental and Therapeutic Medicine 5, no. 2 (2013): 467-470. https://doi.org/10.3892/etm.2012.804