Adaptive prospective ECG-triggered sequence coronary angiography in dual-source CT without heart rate control: Image quality and diagnostic performance

  • Authors:
    • Chang-Jie Pan
    • Nong Qian
    • Tao Wang
    • Xiao-Qiang Tang
    • Yue-Jun Xue
  • View Affiliations

  • Published online on: November 23, 2012     https://doi.org/10.3892/etm.2012.828
  • Pages: 636-642
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Abstract

The aim of this study was to evaluate the accuracy of using second generation dual-source CT (DSCT) to obtain high quality images and diagnostic performance and to reduce the radiation dose in adaptive prospective electrocardiography (ECG)-triggered sequence (CorAdSeq) CT coronary angiography (CTCA) without heart rate control. No prescan β-blockers were administered. Un-enhanced CT and CTCA with adaptive prospective CorAdSeq scanning without heart rate control were performed in 683 consecutive patients divided into two body mass index (BMI) groups: BMI <25 kg/m2 (group A, n=412) and BMI ≥25 kg/m2 (group B, n=271). The image quality and quantitative stenosis of all coronary segments with a diameter ≥1 mm were assessed. The mean heart rate (MHR), heart rate variability (HRV) and radiation dose values were recorded. In 426 cases, the diagnostic performance was evaluated using quantitative conventional coronary angiography as the reference standard. Diagnostic image quality was obtained in 98.5% of segments in group A and in 98.8% of segments in group B, with no significant differences between the groups. No correlations were observed between the image quality score and MHR or HRV (P=0.492, P=0.564, respectively). The effective radiation doses in groups A and B were 2.57±1.01 mSv and 6.36±1.88 mSv, respectively. The sensitivities and specificities of diagnosing coronary heart disease per patient were 99.6% and 97.8% in group A and 99.5% and 97.5% in group B, respectively (P>0.05). Adaptive prospective CorAdSeq scanning, without heart rate control, by second generation DSCT had a high image quality and diagnostic performance for coronary artery stenosis with lower radiation doses.
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February 2013
Volume 5 Issue 2

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Spandidos Publications style
Pan C, Qian N, Wang T, Tang X and Xue Y: Adaptive prospective ECG-triggered sequence coronary angiography in dual-source CT without heart rate control: Image quality and diagnostic performance. Exp Ther Med 5: 636-642, 2013
APA
Pan, C., Qian, N., Wang, T., Tang, X., & Xue, Y. (2013). Adaptive prospective ECG-triggered sequence coronary angiography in dual-source CT without heart rate control: Image quality and diagnostic performance. Experimental and Therapeutic Medicine, 5, 636-642. https://doi.org/10.3892/etm.2012.828
MLA
Pan, C., Qian, N., Wang, T., Tang, X., Xue, Y."Adaptive prospective ECG-triggered sequence coronary angiography in dual-source CT without heart rate control: Image quality and diagnostic performance". Experimental and Therapeutic Medicine 5.2 (2013): 636-642.
Chicago
Pan, C., Qian, N., Wang, T., Tang, X., Xue, Y."Adaptive prospective ECG-triggered sequence coronary angiography in dual-source CT without heart rate control: Image quality and diagnostic performance". Experimental and Therapeutic Medicine 5, no. 2 (2013): 636-642. https://doi.org/10.3892/etm.2012.828