Efficacy of hyperbaric oxygen treatment for depression in the convalescent stage following cerebral hemorrhage

Cao,Hua; Ju,Keju; Zhong,Lingling; Meng,Tao

doi:10.3892/etm.2013.1043

Efficacy of hyperbaric oxygen treatment for depression in the convalescent stage following cerebral hemorrhage

Authors:
- Hua Cao
- Keju Ju
- Lingling Zhong
- Tao Meng
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Affiliations: Department of Neurology, No. 1 People's Hospital Affiliated to Nanjing University of Medical Sciences, Huaian, Jiangsu 223300, P.R. China
Published online on: April 2, 2013 https://doi.org/10.3892/etm.2013.1043
Pages: 1609-1612

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Abstract

The present study aimed to evaluate the clinical efficacy of hyperbaric oxygen (HBO) treatment for depression in the convalescent stage following cerebral hemorrhage. A total of 60 cases of patients with depression in the convalescent stage following cerebral hemorrhage (2‑6 months) were randomly divided into the treatment group (treated with HBO, 30 cases) and the control group (treated with Deanxit, 30 cases). Prior to treatment and at 4 weeks post‑treatment, efficacy was evaluated by the Hamilton Depression Scale (HAMD) and nerve function defect scores. There was a significant difference in the total efficacy between the two groups (P<0.05), and a significant difference in the HAMD scores (P<0.05). There were also significant differences between the pre‑ and post‑treatment HAMD scores within the two groups (both P<0.05). HBO is able to significantly improve the degree of depression in the convalescent stage following cerebral hemorrhage and also promote nerve function recovery.

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