Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Oncology Letters
      • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Biomedical Reports
      • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • Information for Authors
    • Information for Reviewers
    • Information for Librarians
    • Information for Advertisers
    • Conferences
  • Language Editing
Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • For Authors
    • For Reviewers
    • For Librarians
    • For Advertisers
    • Conferences
  • Language Editing
Login Register Submit
  • This site uses cookies
  • You can change your cookie settings at any time by following the instructions in our Cookie Policy. To find out more, you may read our Privacy Policy.

    I agree
Search articles by DOI, keyword, author or affiliation
Search
Advanced Search
presentation
Experimental and Therapeutic Medicine
Join Editorial Board Propose a Special Issue
Print ISSN: 1792-0981 Online ISSN: 1792-1015
Journal Cover
September 2013 Volume 6 Issue 3

Full Size Image

Sign up for eToc alerts
Recommend to Library

Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

Journal Cover
September 2013 Volume 6 Issue 3

Full Size Image

Sign up for eToc alerts
Recommend to Library

  • Article
  • Citations
    • Cite This Article
    • Download Citation
    • Create Citation Alert
    • Remove Citation Alert
    • Cited By
  • Similar Articles
    • Related Articles (in Spandidos Publications)
    • Similar Articles (Google Scholar)
    • Similar Articles (PubMed)
  • Download PDF
  • Download XML
  • View XML
Article

Safety and efficacy of a non‑polymeric paclitaxel‑eluting microporous stent in real‑world percutaneous coronary intervention

  • Authors:
    • Shao‑Peng Wang
    • Rong‑Chong Huang
    • Hao Zhu
    • Bo Zhang
    • Zhen-Guo  Zheng
    • Da Yin
    • Jun-Jie Wang
    • Xu‑Chen Zhou
  • View Affiliations / Copyright

    Affiliations: Department of Cardiology, First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning 116011, P.R. China
  • Pages: 811-815
    |
    Published online on: July 11, 2013
       https://doi.org/10.3892/etm.2013.1217
  • Expand metrics +
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Metrics: Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )
Cited By (CrossRef): 0 citations Loading Articles...

This article is mentioned in:



Abstract

At present, there is an increasing focus on stents that have a biodegradable polymer coating, rather than a permanent polymer coating. This is due to the fact that following the implantation of a drug‑eluting stent (DES) with a permanent polymer coating, the continued existence of the coating may result in a foreign body reaction and delayed re‑endothelialization. The aim of the present study was to evaluate the safety and efficacy of a non‑polymeric paclitaxel‑eluting microporous (YINYI™) stent in real‑life percutaneous coronary intervention (PCI) for patients with coronary artery disease (CAD). A total of 686 YINYI™ stents were implanted in 404 patients with CAD in a PCI procedure and outpatient follow‑ups were performed 1, 6, 12 and 15 months subsequent to the PCI, respectively. The observation endpoints were major adverse cardiac events (MACEs), including cardiac death, non‑fatal myocardial infarction (MI), restenosis, target lesion revascularization, stent thrombosis and recurrence of angina pectoris. The average follow‑up time was 15 months. The results revealed that the cumulative incidences of MACEs were as follows: mortality, 0.99%; non‑fatal MI, 0.74%; restenosis, 4.0%; and target lesion revascularization, 2.7%. The results at the short‑ and long‑term clinical follow‑ups indicated that YINYI™ stents are effective and safe for use in PCI for patients with CAD.
View Figures
View References

1 

Blagojevic A, Delaney JA, Lévesque LE, Dendukuri N, Boivin JF and Brophy JM: Investigation of an interaction between statins and clopidogrel after percutaneous coronary intervention: a cohort study. Pharmacoepidemiol Drug Saf. 18:362–369. 2009. View Article : Google Scholar : PubMed/NCBI

2 

World Health Organization. The top ten causes of death. http://www.who.int/mediacentre/factsheets/fs310/en/index.htmluri. Accessed September 4, 2007

3 

Lemos PA, Hoye A, Goedhart D, et al: Clinical, angiographic, and procedural predictors of angiographic restenosis after sirolimus-eluting stent implantation in complex patients: an evaluation from the Rapamycin-Eluting Stent Evaluated at Rotterdam Cardiology Hospital (RESEARCH) study. Circulation. 109:1366–1370. 2004. View Article : Google Scholar

4 

Lemos PA, Serruys PW, van Domburg RT, et al: Unrestricted utilization of sirolimus-eluting stents compared with conventional bare stent implantation in the ‘real world’: The Rapamycin-Eluting Stent Evaluated At Rotterdam Cardiology Hospital (RESEARCH) registry. Circulation. 109:190–195. 2004.PubMed/NCBI

5 

Harjai KJ, Sattur S, Orshaw P and Boura J: Long-term safety and effectiveness of drug-eluting stents compared to bare metal stents following successful PCI in non-ST-elevation myocardial infarction: findings from the Guthrie Health Off-Label StenT (GHOST) Registry. J Interv Cardiol. 25:28–36. 2012. View Article : Google Scholar

6 

Green SM, Selzer F, Mulukutla SR, et al: Comparison of bare-metal and drug-eluting stents in patients with chronic kidney disease (from the NHLBI Dynamic Registry). Am J Cardiol. 108:1658–1664. 2011. View Article : Google Scholar : PubMed/NCBI

7 

Stone GW, Ellis SG, Cannon L, et al; TAXUS V Investigators. Comparison of a polymer-based paclitaxel-eluting stent with a bare metal stent in patients with complex coronary artery disease: a randomized controlled trial. JAMA. 294:1215–1223. 2005. View Article : Google Scholar

8 

Pfisterer M, Brunner-La Rocca HP, Buser PT, et al: Late clinical events after clopidogrel discontinuation may limit the benefit of drug-eluting stents: an observation study of drug-eluting versus bare-metal stents. J Am Coll Cardiol. 48:2584–2591. 2006. View Article : Google Scholar : PubMed/NCBI

9 

Lee MG, Jeong MH, Ahn Y, et al; Korea Acute Myocardial Infarction Registry Investigators. Comparison of paclitaxel-, sirolimus-, and zotarolimus-eluting stents in patients with acute ST-segment elevation myocardial infarction and metabolic syndrome. Circ J. 75:2120–2127. 2011. View Article : Google Scholar : PubMed/NCBI

10 

Mauri L, Hsieh WH, Massaro JM, Ho KK, D’Agostino R and Cutlip DE: Stent thrombosis in randomized clinical trials of drug-eluting stents. N Eng J Med. 356:1020–1029. 2007. View Article : Google Scholar : PubMed/NCBI

11 

Wykrzykowska JJ, Garg S, Onuma Y, et al: Implantation of the biodegradable polymer biolimus-eluting stent in patients with high SYNTAX score is associated with decreased cardiac mortality compared to a permanent polymer sirolimus-eluting stent: two year follow-up results from the ‘all-comers’ LEADERS trial. EuroIntervention. 7:605–613. 2011.PubMed/NCBI

12 

Zhang RY, Zhang Q, Zhu JZ, et al: Safety and efficacy of polymer-free paclitaxel-eluting microporous stent in real-world practice: 1-year follow-up of the SERY-I registry. Chin Med J (Engl). 124:3521–3526. 2011.PubMed/NCBI

13 

Vranckx P, Kint PP, Morel MA, et al: Identifying stent thrombosis, a critical appraisal of the academic research consortium (ARC) consensus definitions: a lighthouse and as a toe in the water. EuroIntervention. 4(Suppl C): C39–44. 2008.PubMed/NCBI

14 

Kwan TW, Cherukuri S, Huang Y, et al: Feasibility and safety of 7F sheathless guiding catheter during transradial coronary intervention. Catheter Cardiovasc Interv. 80:274–280. 2012. View Article : Google Scholar : PubMed/NCBI

15 

Chieffo A, Morici N, Maisano F, et al: Percutaneous treatment with drug-eluting stent implantation versus bypass surgery for unprotected left main stenosis: a single-center experience. Circulation. 113:2542–2547. 2006. View Article : Google Scholar

16 

Virmani R, Guagliumi G, Farb A, et al: Localized hypersensitivity and late coronary thrombosis secondary to a sirolimus-eluting stent: should we be cautious? Circulation. 109:701–705. 2004. View Article : Google Scholar : PubMed/NCBI

17 

Steffel J, Eberli FR, Lüscher TF and Tanner FC: Drug-eluting stents - what should be improved? Ann Med. 40:242–252. 2008. View Article : Google Scholar : PubMed/NCBI

18 

Stone GW, Moses JW, Ellis SG, et al: Safety and efficacy of sirolimus- and paclitaxel-eluting coronary stents. N Engl J Med. 356:998–1008. 2007. View Article : Google Scholar : PubMed/NCBI

19 

Wykrzykowska JJ, Serruys PW, Onuma Y, et al: Impact of vessel size on angiographic and clinical outcomes of revascularization with biolimus-eluting stent with biodegradable polymer and sirolimus-eluting stent with durable polymer: the LEADERS trial substudy. JACC Cardiovasc Interv. 2:861–870. 2009. View Article : Google Scholar : PubMed/NCBI

20 

Chevalier B, Silber S, Park SJ, et al; NOBORI 1 Clinical Investigators. Randomized comparison of the Nobori Biolimus A9-eluting coronary stent with the Taxus Liberté paclitaxel-eluting coronary stent in patients with stenosis in native coronary arteries: the NOBORI 1 trial - Phase 2. Circ Cardiovasc Interv. 2:188–195. 2009.

21 

Floyd KC, Jayne JE, Kaplan AV, et al: Age-based differences of percutaneous coronary intervention in the drug-eluting stent era. J Interv Cardiol. 19:381–387. 2006. View Article : Google Scholar : PubMed/NCBI

22 

Li Y, Li CX, Wang HC, et al: Efficacy and safety of Firebird sirolimus-eluting stent in treatment of complex coronary lesions in Chinese patients: one-year clinical and eight-month angiographic outcomes from the FIREMAN registry. Chin Med J (Engl). 124:817–824. 2011.PubMed/NCBI

23 

Yu M, Zhou YJ, Wang ZJ, et al: A comparison of clinical outcomes of Chinese sirolimus-eluting stents versus foreign sirolimus-eluting stents for the treatment of coronary artery disease. Neth Heart J. 19:418–422. 2011. View Article : Google Scholar : PubMed/NCBI

Related Articles

  • Abstract
  • View
  • Download
  • Twitter
Copy and paste a formatted citation
Spandidos Publications style
Wang SP, Huang RC, Zhu H, Zhang B, Zheng Z, Yin D, Wang J and Zhou XC: Safety and efficacy of a non‑polymeric paclitaxel‑eluting microporous stent in real‑world percutaneous coronary intervention. Exp Ther Med 6: 811-815, 2013.
APA
Wang, S., Huang, R., Zhu, H., Zhang, B., Zheng, Z., Yin, D. ... Zhou, X. (2013). Safety and efficacy of a non‑polymeric paclitaxel‑eluting microporous stent in real‑world percutaneous coronary intervention. Experimental and Therapeutic Medicine, 6, 811-815. https://doi.org/10.3892/etm.2013.1217
MLA
Wang, S., Huang, R., Zhu, H., Zhang, B., Zheng, Z., Yin, D., Wang, J., Zhou, X."Safety and efficacy of a non‑polymeric paclitaxel‑eluting microporous stent in real‑world percutaneous coronary intervention". Experimental and Therapeutic Medicine 6.3 (2013): 811-815.
Chicago
Wang, S., Huang, R., Zhu, H., Zhang, B., Zheng, Z., Yin, D., Wang, J., Zhou, X."Safety and efficacy of a non‑polymeric paclitaxel‑eluting microporous stent in real‑world percutaneous coronary intervention". Experimental and Therapeutic Medicine 6, no. 3 (2013): 811-815. https://doi.org/10.3892/etm.2013.1217
Copy and paste a formatted citation
x
Spandidos Publications style
Wang SP, Huang RC, Zhu H, Zhang B, Zheng Z, Yin D, Wang J and Zhou XC: Safety and efficacy of a non‑polymeric paclitaxel‑eluting microporous stent in real‑world percutaneous coronary intervention. Exp Ther Med 6: 811-815, 2013.
APA
Wang, S., Huang, R., Zhu, H., Zhang, B., Zheng, Z., Yin, D. ... Zhou, X. (2013). Safety and efficacy of a non‑polymeric paclitaxel‑eluting microporous stent in real‑world percutaneous coronary intervention. Experimental and Therapeutic Medicine, 6, 811-815. https://doi.org/10.3892/etm.2013.1217
MLA
Wang, S., Huang, R., Zhu, H., Zhang, B., Zheng, Z., Yin, D., Wang, J., Zhou, X."Safety and efficacy of a non‑polymeric paclitaxel‑eluting microporous stent in real‑world percutaneous coronary intervention". Experimental and Therapeutic Medicine 6.3 (2013): 811-815.
Chicago
Wang, S., Huang, R., Zhu, H., Zhang, B., Zheng, Z., Yin, D., Wang, J., Zhou, X."Safety and efficacy of a non‑polymeric paclitaxel‑eluting microporous stent in real‑world percutaneous coronary intervention". Experimental and Therapeutic Medicine 6, no. 3 (2013): 811-815. https://doi.org/10.3892/etm.2013.1217
Follow us
  • Twitter
  • LinkedIn
  • Facebook
About
  • Spandidos Publications
  • Careers
  • Cookie Policy
  • Privacy Policy
How can we help?
  • Help
  • Live Chat
  • Contact
  • Email to our Support Team