Catheter‑directed thrombolytic therapy combined with angioplasty for hepatic vein obstruction in Budd‑Chiari syndrome complicated by thrombosis

Zhang,Qingqiao; Xu,Hao; Zu,Maoheng; Gu,Yuming; Wei,Ning; Wang,Wenliang; Gao,Zhikang; Shen,Bin

doi:10.3892/etm.2013.1239

October 2013 Volume 6 Issue 4

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October 2013 Volume 6 Issue 4

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Article

Catheter‑directed thrombolytic therapy combined with angioplasty for hepatic vein obstruction in Budd‑Chiari syndrome complicated by thrombosis

Authors:
- Qingqiao Zhang
- Hao Xu
- Maoheng Zu
- Yuming Gu
- Ning Wei
- Wenliang Wang
- Zhikang Gao
- Bin Shen
View Affiliations / Copyright

Affiliations: Department of Interventional Radiology, The Affiliated Hospital of Xuzhou Medical College, Xuzhou, Jiangsu 221006, P.R. China
Pages: 1015-1021
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Published online on: July 30, 2013

https://doi.org/10.3892/etm.2013.1239
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Abstract

The aim of this study was to assess the efficacy and safety of catheter‑directed thrombolysis combined with angioplasty in the treatment of hepatic vein obstruction in Budd‑Chiari syndrome (BCS) complicated by thrombosis. In 14 cases of BCS, the patients with hepatic vein obstruction complicated by thrombosis who underwent catheter‑directed urokinase thrombolysis, balloon dilatation and/or stent placement were followed up with an ultrasound examination of the liver. Among the 13 cases of successful treatment, one hepatic vein was recanalized in 12 patients (right hepatic vein, seven cases; left hepatic vein, three cases; middle hepatic vein, one case and accessory hepatic vein, one case) and two hepatic veins (right and left) were recanalized in one patient without serious complications, such as bleeding and pulmonary embolism. There was one patient in whom the treatment was unsuccessful. During an average follow‑up period of 24.8±19.6 months, hepatic vein restenosis was observed in one patient in the sixth month after opperation; however, a successful result was obtained following a second balloon dilatation. The remaining 12 patients did not demonstrate any recurrence of restenosis or thrombosis. Catheter‑directed thrombolysis combined with angioplasty was observed to be an effective and safe method for the treatment of hepatic vein obstruction in BCS complicated by thrombosis.

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Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

Catheter‑directed thrombolytic therapy combined with angioplasty for hepatic vein obstruction in Budd‑Chiari syndrome complicated by thrombosis

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