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Article

Biomechanical analysis of the spinal cord in Brown-Séquard syndrome

  • Authors:
    • Norihiro Nishida
    • Tsukasa Kanchiku
    • Yoshihiko Kato
    • Yasuaki Imajo
    • Syunichi Kawano
    • Toshihiko Taguchi
  • View Affiliations / Copyright

    Affiliations: Department of Orthopaedic Surgery, Yamaguchi University Graduate School of Medicine, Yamaguchi 755-850, Japan, Faculty of Engineering, Yamaguchi University, Yamaguchi 755-8611, Japan
  • Pages: 1184-1188
    |
    Published online on: September 3, 2013
       https://doi.org/10.3892/etm.2013.1286
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Abstract

Complete Brown-Séquard syndrome (BSS) resulting from chronic compression is rare and the majority of patients present with incomplete BSS. In the present study, we investigated why the number of cases of complete BSS due to chronic compression is limited. A 3-dimensional finite element method (3D-FEM) spinal cord model was used in this study. Anterior compression was applied to 25, 37.5, 50, 62.5 and 75% of the length of the transverse diameter of the spinal cord. The degrees of static compression were 10, 20 and 30% of the anteroposterior (AP) diameter of the spinal cord. When compression was applied to >62.5 or <37.5% of the length of the transverse diameter of the spinal cord, no increases in stress indicative of complete BSS were observed. Compression of 50% of the length of the transverse diameter of the spinal cord resulted in a stress distribution that may correspond to that in complete BSS cases, when the degree of compression was 30% of the AP diameter of the spinal cord. However, compression within such a limited range rarely occurs in clinical situations and, thus, this may explain why the number of cases with complete BSS is low.
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1. 

Kraus JA, Stuper BK and Berlit P: Multiple sclerosis presenting with Brown-Séquard syndrome. J Neurol Sci. 156:112–113. 1998.

2. 

Fisher RG: Protrusions of thoracic disc. The factor of herniation through the dura matter. J Neurosurg. 22:591–593. 1965. View Article : Google Scholar : PubMed/NCBI

3. 

Love JG and Schorn VG: Thoracic-disc protrusions. JAMA. 191:627–631. 1965. View Article : Google Scholar

4. 

Koehler PJ and Endtz LJ: The Brown-Séquard syndrome. True or false? Arch Neurol. 43:921–924. 1986.

5. 

Persson C, Summers J and Hall RM: The importance of fluid-structure interaction in spinal trauma models. J Neurotrauma. 28:113–125. 2011. View Article : Google Scholar

6. 

Ichihara K, Taguchi T, Shimada Y, Sakuramoto I, Kawano S and Kawai S: Gray matter of the bovine cervical spinal cord is mechanically more rigid and fragile than the white matter. J Neurotrauma. 18:361–367. 2001. View Article : Google Scholar : PubMed/NCBI

7. 

Ichihara K, Taguchi T, Sakuramoto I, Kawano S and Kawai S: Mechanism of the spinal cord injury and the cervical spondylotic myelopathy: new approach based on the mechanical features of the spinal cord white and gray matter. J Neurosurg. 99(Suppl 3): 278–285. 2003.PubMed/NCBI

8. 

Tunturi AR: Elasticity of the spinal cord, pia, and denticulate ligament in the dog. J Neurosurg. 48:975–979. 1978. View Article : Google Scholar : PubMed/NCBI

9. 

Brown Sequard CE: De la transmission des impressions sensitives par la moelle epiniere. CR Soc Biol. 1:192–194. 1849.

10. 

Kobayashi N, Asamoto S, Doi H and Sugiyama H: Brown-Séquard syndrome produced by cervical disc herniation: report of two cases and review of the literature. Spine J. 23:530–533. 2003.

11. 

Kohno M, Takahashi H, Yamakawa K, Ide K and Segawa H: Postoperative prognosis of Brown-Séquard-type myelopathy in patients with cervical lesions. Surg Neurol. 51:241–246. 1999.

12. 

Mastronardi and Ruggeri A: Cervical disc herniation producing Brown-Séquard syndrome: case report. Spine (Phila Pa 1976). 29:E28–E31. 2004.PubMed/NCBI

13. 

Jomin M, Lesoin F, Lozes G, et al: Herniated cervical discs. Analysis of a series of 230 cases. Acta Neurochir (Wien). 79:107–113. 1986. View Article : Google Scholar : PubMed/NCBI

14. 

Choi KB, Lee CD, Chung DJ and Lee SH: Cervical disc herniation as a cause of Brown-Séquard syndrome. J Korean Neurosurg Soc. 46:505–510. 2009.

15. 

Arce CA and Dohrmann GJ: Herniated thoracic disks. Neurol Clin. 3:383–392. 1985.

16. 

Massicotte EM, Montanera WR, Ross Fleming JF, Tucker WS, Willinsky R, TerBrugge K and Fehlings MG: Idiopathic spinal cord herniation: report of eight cases and review of the literature. Spine (Phila Pa 1976). 27:E233–E241. 2002. View Article : Google Scholar : PubMed/NCBI

17. 

Miyaguchi M, Nakamura H, Shakudo M, Inoue Y and Yamano Y: Idiopathic spinal cord herniation associated with intervertebral disc extrusion: a case report and review of the literature. Spine (Phila Pa 1976). 26:1090–1094. 2001. View Article : Google Scholar : PubMed/NCBI

18. 

Wada E, Yonebu K and Kang J: Idiopathic spinal cord herniation: report of three cases and review of the literature. Spine (Phila Pa 1976). 25:1984–1988. 2000. View Article : Google Scholar

19. 

White BD and Tsegaye M: Idiopathic anterior spinal cord hernia: under-recognized cause of thoracic myelopathy. Br J Neurosurg. 18:246–249. 2004. View Article : Google Scholar : PubMed/NCBI

20. 

Sasari M, Ozer AF, Vural M and Sarioglu AC: Idiopathic spinal cord herniation: case report and review of the literature. J Spinal Cord Med. 32:86–94. 2009.PubMed/NCBI

21. 

Kato Y, Kataoka H, Ichihara K, et al: Biomechanical study of cervical flexion myelopathy using a three-dimensional finite element method. J Neurosurg Spine. 8:436–441. 2008. View Article : Google Scholar : PubMed/NCBI

22. 

Kato Y, Kanchiku T, Imajo Y, et al: Flexion model simulating spinal cord injury without radiographic abnormality in patients with ossification of the longitudinal ligament: the influence of flexion speed on the cervical spine. J Spinal Cord Med. 32:555–559. 2009.

23. 

Kato Y, Kanchiku T, Imajo Y, et al: Biomechanical study of the effect of the degree of static compression of the spinal cord in ossification of the posterior longitudinal ligament. J Neurosurg Spine. 12:301–305. 2010. View Article : Google Scholar : PubMed/NCBI

24. 

Li XF and Dai LY: Three-dimensional finite element model of the cervical spinal cord: preliminary results of injury mechanism analysis. Spine (Phila Pa 1976). 34:1140–1147. 2009. View Article : Google Scholar : PubMed/NCBI

25. 

Li XF and Dai LY: Acute central cord syndrome: injury mechanisms and stress features. Spine (Phila Pa 1976). 35:E955–E964. 2010. View Article : Google Scholar : PubMed/NCBI

26. 

Nishida N, Kato Y, Imajo Y, Kawano S and Taguchi T: Biomechanical study of the spinal cord in thoracic ossification of the posterior longitudinal ligament. J Spinal Cord Med. 34:518–522. 2011. View Article : Google Scholar : PubMed/NCBI

27. 

Nishida N, Kato Y, Imajo Y, Kawano S and Taguchi T: Biomechanical analysis of cervical spondylotic myelopathy: the influence of dynamic factors and morphometry of the spinal cord. J Spinal Cord Med. 35:256–261. 2012. View Article : Google Scholar : PubMed/NCBI

28. 

Henderson FC, Geddes JF, Vaccaro AR, Woodard E, Berry KJ and Benzel EC: Stretch-associated injury in cervical spondylotic myelopathy: new concept and review. Neurosurgery. 56:1101–1113. 2005.PubMed/NCBI

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Copy and paste a formatted citation
Spandidos Publications style
Nishida N, Kanchiku T, Kato Y, Imajo Y, Kawano S and Taguchi T: Biomechanical analysis of the spinal cord in Brown-Séquard syndrome. Exp Ther Med 6: 1184-1188, 2013.
APA
Nishida, N., Kanchiku, T., Kato, Y., Imajo, Y., Kawano, S., & Taguchi, T. (2013). Biomechanical analysis of the spinal cord in Brown-Séquard syndrome. Experimental and Therapeutic Medicine, 6, 1184-1188. https://doi.org/10.3892/etm.2013.1286
MLA
Nishida, N., Kanchiku, T., Kato, Y., Imajo, Y., Kawano, S., Taguchi, T."Biomechanical analysis of the spinal cord in Brown-Séquard syndrome". Experimental and Therapeutic Medicine 6.5 (2013): 1184-1188.
Chicago
Nishida, N., Kanchiku, T., Kato, Y., Imajo, Y., Kawano, S., Taguchi, T."Biomechanical analysis of the spinal cord in Brown-Séquard syndrome". Experimental and Therapeutic Medicine 6, no. 5 (2013): 1184-1188. https://doi.org/10.3892/etm.2013.1286
Copy and paste a formatted citation
x
Spandidos Publications style
Nishida N, Kanchiku T, Kato Y, Imajo Y, Kawano S and Taguchi T: Biomechanical analysis of the spinal cord in Brown-Séquard syndrome. Exp Ther Med 6: 1184-1188, 2013.
APA
Nishida, N., Kanchiku, T., Kato, Y., Imajo, Y., Kawano, S., & Taguchi, T. (2013). Biomechanical analysis of the spinal cord in Brown-Séquard syndrome. Experimental and Therapeutic Medicine, 6, 1184-1188. https://doi.org/10.3892/etm.2013.1286
MLA
Nishida, N., Kanchiku, T., Kato, Y., Imajo, Y., Kawano, S., Taguchi, T."Biomechanical analysis of the spinal cord in Brown-Séquard syndrome". Experimental and Therapeutic Medicine 6.5 (2013): 1184-1188.
Chicago
Nishida, N., Kanchiku, T., Kato, Y., Imajo, Y., Kawano, S., Taguchi, T."Biomechanical analysis of the spinal cord in Brown-Séquard syndrome". Experimental and Therapeutic Medicine 6, no. 5 (2013): 1184-1188. https://doi.org/10.3892/etm.2013.1286
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