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Article

Non-invasive evaluation of hemodynamics in pulmonary hypertension by a Septal angle measured by computed tomography pulmonary angiography: Comparison with right‑heart catheterization and association with N-terminal pro-B-type natriuretic peptide

  • Authors:
    • Qiang Tang
    • Min Liu
    • Zhanhong Ma
    • Xiaojuan Guo
    • Tuguang Kuang
    • Yuanhua Yang
  • View Affiliations / Copyright

    Affiliations: Department of Cardiology, Shougang Hospital, Peking University, Beijing 100144, P.R. China, Department of Radiology, Beijing Chaoyang Hospital, Capital Medical University, Beijing 100020, P.R. China, Respiratory Diseases Research Center, Capital Medical University, Beijing 100020, P.R. China
  • Pages: 1350-1358
    |
    Published online on: September 30, 2013
       https://doi.org/10.3892/etm.2013.1324
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Abstract

The septal angle, an angle between the interventricular septum and the line connecting the sternum midpoint and thoracic vertebral spinous process, as measured by computed tomographic pulmonary angiography (CTPA), has been observed to be increased in patients with pulmonary hypertension (PH), but its meaning remains unclear. The aim of this study was to investigate the potential role of the septal angle in evaluating hemodynamics and its association with N-terminal pro-B-type natriuretic peptide (NT-proBNP) in patients with PH. Patients with PH (n=106), including 76 with chronic thromboembolic pulmonary hypertension (CTEPH) and 30 with pulmonary artery hypertension (PAH), were retrospectively reviewed. The patients underwent CTPA prior to right-heart catheterization. The septal angle was measured on transversal CTPA images. Hemodynamic parameters were evaluated by right-heart catheterization. The level of plasma NT-proBNP was measured by enzyme‑linked sandwich immunoassay. The septal angle had a moderate correlation with cardiac output (CO; r=-0.535, P=0.000) and a high correlation with pulmonary vascular resistance (PVR; r=0.642, P=0.000). The mean level of NT-proBNP in PH was 1,716.09±1,498.30 pg/ml, which correlated with the septal angle (r=0.693, P=0.000). In a stepwise forward regression analysis, the Septal angle was entered into the final equation for predicting PVR, leading to the following equation: PVR = 28.256 x Septal angle - 728.72. In CTEPH, the Septal angle strongly correlated with NT-proBNP (r=0.668, P=0.000) and PVR (r=0.676, P=0.000). In PAH, the Septal angle strongly correlated with NT-proBNP (r=0.616, P=0.003) and PVR (r=0.623, P=0.000). The CTPA‑derived Septal angle is a superior predictor for evaluating and monitoring the level of NT-proBNP and PVR in patients with PH.
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1 

McLaughlin VV, Archer SL, Badesch DB, et al: ACCF/AHA 2009 expert consensus document on pulmonary hypertension: a report of the American College of Cardiology Foundation Task Force on Expert Consensus Documents and the American Heart Association developed in collaboration with the American College of Chest Physicians; American Thoracic Society, Inc.; and the Pulmonary Hypertension Association. J Am Coll Cardiol. 53:1573–1619. 2009.

2 

Galiè N, Hoeper MM, Humbert M, et al; ESC Committee for Practice Guidelines (CPG). Guidelines for the diagnosis and treatment of pulmonary hypertension: the Task Force for the Diagnosis and Treatment of Pulmonary Hypertension of the European Society of Cardiology (ESC) and the European Respiratory Society (ERS), endorsed by the International Society of Heart and Lung Transplantation (ISHLT). Eur Heart J. 30:2493–2537. 2009.

3 

Guillinta P, Peterson KL and Ben-Yehuda O: Cardiac catheterization techniques in pulmonary hypertension. Cardiol Clin. 22:401–415. 2004. View Article : Google Scholar : PubMed/NCBI

4 

Seino Y, Ogawa A, Yamashita T, et al: Application of NT-proBNP and BNP measurements in cardiac care: a more discerning marker for the detection and evaluation of heart failure. Eur J Heart Fail. 6:295–300. 2004. View Article : Google Scholar : PubMed/NCBI

5 

Pruszczyk P: N-terminal pro-brain natriuretic peptide as an indicator of right ventricular dysfunction. J Card Fail. 11(5 Suppl): S65–S69. 2005. View Article : Google Scholar : PubMed/NCBI

6 

Fijalkowska A, Kurzyna M, Torbicki A, et al: Serum N-terminal brain natriuretic peptide as a prognostic parameter in patients with pulmonary hypertension. Chest. 129:1313–1321. 2006. View Article : Google Scholar : PubMed/NCBI

7 

Casserly B and Klinger JR: Brain natriuretic peptide in pulmonary arterial hypertension: biomarker and potential therapeutic agent. Drug Des Devel Ther. 29:269–287. 2009.PubMed/NCBI

8 

Hoey ET, Gopalan D, Agrawal SK and Screaton NJ: Cardiac causes of pulmonary arterial hypertension: assessment with multidetector CT. Eur Radiol. 19:2557–2568. 2009. View Article : Google Scholar : PubMed/NCBI

9 

Ghuysen A, Ghaye B, Willems V, et al: Computed tomographic pulmonary angiography and prognostic significance in patients with acute pulmonary embolism. Thorax. 60:956–961. 2005. View Article : Google Scholar : PubMed/NCBI

10 

Collomb D, Paramelle PJ, Calaque O, et al: Severity assessment of acute pulmonary embolism: evaluation using helical CT. Eur Radiol. 13:1508–1514. 2003. View Article : Google Scholar : PubMed/NCBI

11 

Nural MS, Elmali M, Findik S, et al: Computed tomographic pulmonary angiography in the assessment of severity of acute pulmonary embolism and right ventricular dysfunction. Acta Radiol. 50:629–637. 2009. View Article : Google Scholar

12 

Johnson TR, Nikolaou K, Becker A, Leber AW, Rist C, Wintersperger BJ, Reiser MF and Becker CR: Dual-source CT for chest pain assessment. Eur Radiol. 18:773–780. 2008.PubMed/NCBI

13 

Revel MP, Faivre JB, Remy-Jardin M, Delannoy-Deken V, Duhamel A and Remy J: Pulmonary hypertension: ECG-gated 64-section CT angiographic evaluation of new functional parameters as diagnostic criteria. Radiology. 250:558–566. 2009. View Article : Google Scholar : PubMed/NCBI

14 

Doğan H, Kroft LJ, Huisman MV, van der Geest RJ and de Roos A: Right ventricular function in patients with acute pulmonary embolism: analysis with electrocardiography-synchronized multi-detector row CT. Radiology. 242:78–84. 2007.PubMed/NCBI

15 

Liu M, Ma Z, Guo X, Zhang H, Yang Y and Wang C: Computed tomographic pulmonary angiography in the assessment of severity of chronic thromboembolic pulmonary hypertension and right ventricular dysfunction. Eur J Radiol. 80:e462–e469. 2011. View Article : Google Scholar

16 

Liu M, Ma ZH, Guo XJ, et al: A septal angle measured on computed tomographic pulmonary angiography can noninvasively estimate pulmonary vascular resistance in patients with chronic thromboembolic pulmonary hypertension. J Thorac Imaging. 27:325–330. 2012. View Article : Google Scholar

17 

Liu M, Ma Z, Guo X, Chen X, Yang Y and Wang C: Cardiovascular parameters of computed tomographic pulmonary angiography to assess pulmonary vascular resistance in patients with chronic thromboembolic pulmonary hypertension. Int J Cardiol. 164:295–300. 2013. View Article : Google Scholar

18 

Tramarin R, Torbicki A, Marchandise B, Laaban JP and Morpurgo M; Working Group on Noninvasive Evaluation of Pulmonary Artery Pressure. European Office of the World Health Organization, Copenhagen. Doppler echocardiographic evaluation of pulmonary artery pressure in chronic obstructive pulmonary disease. A European multicentre study. Eur Heart J. 12:103–111. 1991.

19 

Ganz W, Donoso R, Marcus HS, Forrester JS and Swan HJ: A new technique for measurement of cardiac output by thermodilution in man. Am J Cardiol. 27:392–396. 1971. View Article : Google Scholar : PubMed/NCBI

20 

McMichael J and Sharpey-Schafer EP: Cardiac output in man by a direct fick method: Effects of posture, venous pressure change, atropine, and adrenaline. Br Heart J. 6:33–40. 1944. View Article : Google Scholar : PubMed/NCBI

21 

Bogaard HJ, Abe K, Vonk Noordegraaf A and Voelkel NF: The right ventricle under pressure: cellular and molecular mechanisms of right-heart failure in pulmonary hypertension. Chest. 135:794–804. 2009. View Article : Google Scholar : PubMed/NCBI

22 

Delcroix M, Vonk Noordegraaf A, Fadel E, Lang I, Simonneau G and Naeije R: Vascular and right ventricular remodelling in chronic thromboembolic pulmonary hypertension. Eur Respir J. 41:224–232. 2013. View Article : Google Scholar : PubMed/NCBI

23 

Sitbon O, Humbert M, Nunes H, et al: Long-term intravenous epoprostenol infusion in primary pulmonary hypertension: prognostic factors and survival. J Am Coll Cardiol. 40:780–788. 2002. View Article : Google Scholar : PubMed/NCBI

24 

Raymond RJ, Hinderliter AL, Willis PW, Ralph D, et al: Echocardiographic predictors of adverse outcomes in primary pulmonary hypertension. J Am Coll Cardiol. 39:1214–1219. 2002. View Article : Google Scholar : PubMed/NCBI

25 

McGoon M, Gutterman D, Steen V, Barst R, et al: Screening, early detection, and diagnosis of pulmonary arterial hypertension: ACCP evidence based clinical practice guidelines. Chest. 126(1 Suppl): 14S–34S. 2004. View Article : Google Scholar : PubMed/NCBI

26 

Andreassen AK, Wergeland R, Simonsen S, Geiran O, Guevara C and Ueland T: N-terminal pro-B-type natriuretic peptide as an indicator of disease severity in a heterogeneous group of patients with chronic precapillary pulmonary hypertension. Am J Cardiol. 98:525–529. 2006. View Article : Google Scholar : PubMed/NCBI

27 

Nagaya N, Nishikimi T, Okano Y, et al: Plasma brain natriuretic peptide levels increase in proportion to the extent of right ventricular dysfunction in pulmonary hypertension. J Am Coll Cardiol. 31:202–208. 1998. View Article : Google Scholar

28 

McDonagh TA, Holmer S, Raymond I, Luchner A, Hildebrant P and Dargie HJ: NT-proBNP and the diagnosis of heart failure: a pooled analysis of three European epidemiological studies. Eur J Heart Fail. 6:269–273. 2004. View Article : Google Scholar : PubMed/NCBI

29 

Yap LB, Ashrafian H, Mukerjee D, Coghlan JG and Timms PM: The natriuretic peptides and their role in disorders of right heart dysfunction and pulmonary hypertension. Clin Biochem. 37:847–856. 2004. View Article : Google Scholar : PubMed/NCBI

30 

D'Armini AM, Cattadori B, Monterosso C, et al: Pulmonary thromboendarterectomy in patients with chronic thromboembolic pulmonary hypertension: hemodynamic characteristics and changes. Eur J Cardiothorac Surg. 18:696–702. 2000. View Article : Google Scholar

31 

Reesink HJ, Tulevski II, Marcus JT, Boomsma F, et al: Brain natriuretic peptide as noninvasive marker of the severity of right ventricular dysfunction in chronic thromboembolic pulmonary hypertension. Ann Thorac Surg. 84:537–543. 2007. View Article : Google Scholar

32 

Jamieson SW, Kapelanski DP, Sakakibara N, et al: Pulmonary endarterectomy: experience and lessons learned in 1,500 cases. Ann Thorac Surg. 76:1457–1464. 2003. View Article : Google Scholar : PubMed/NCBI

33 

Badesch DB, Champion HC, Sanchez MA, et al: Diagnosis and assessment of pulmonary arterial hypertension. J Am Coll Cardiol. 54(1 Suppl): S55–S66. 2009. View Article : Google Scholar : PubMed/NCBI

34 

Mukerjee D, Yap LB, Holmes AM, Nair D, et al: Significance of plasma N-terminal pro-brain natriuretic peptide in patients with systemic sclerosis-related pulmonary arterial hypertension. Respir Med. 97:1230–1236. 2003. View Article : Google Scholar : PubMed/NCBI

35 

Souza R, Jardim C, Julio Cesar Fernandes C, Silveira Lapa M, et al: NT-proBNP as a tool to stratify disease severity in pulmonary arterial hypertension. Respir Med. 101:69–75. 2007. View Article : Google Scholar : PubMed/NCBI

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Copy and paste a formatted citation
Spandidos Publications style
Tang Q, Liu M, Ma Z, Guo X, Kuang T and Yang Y: Non-invasive evaluation of hemodynamics in pulmonary hypertension by a Septal angle measured by computed tomography pulmonary angiography: Comparison with right‑heart catheterization and association with N-terminal pro-B-type natriuretic peptide. Exp Ther Med 6: 1350-1358, 2013.
APA
Tang, Q., Liu, M., Ma, Z., Guo, X., Kuang, T., & Yang, Y. (2013). Non-invasive evaluation of hemodynamics in pulmonary hypertension by a Septal angle measured by computed tomography pulmonary angiography: Comparison with right‑heart catheterization and association with N-terminal pro-B-type natriuretic peptide. Experimental and Therapeutic Medicine, 6, 1350-1358. https://doi.org/10.3892/etm.2013.1324
MLA
Tang, Q., Liu, M., Ma, Z., Guo, X., Kuang, T., Yang, Y."Non-invasive evaluation of hemodynamics in pulmonary hypertension by a Septal angle measured by computed tomography pulmonary angiography: Comparison with right‑heart catheterization and association with N-terminal pro-B-type natriuretic peptide". Experimental and Therapeutic Medicine 6.6 (2013): 1350-1358.
Chicago
Tang, Q., Liu, M., Ma, Z., Guo, X., Kuang, T., Yang, Y."Non-invasive evaluation of hemodynamics in pulmonary hypertension by a Septal angle measured by computed tomography pulmonary angiography: Comparison with right‑heart catheterization and association with N-terminal pro-B-type natriuretic peptide". Experimental and Therapeutic Medicine 6, no. 6 (2013): 1350-1358. https://doi.org/10.3892/etm.2013.1324
Copy and paste a formatted citation
x
Spandidos Publications style
Tang Q, Liu M, Ma Z, Guo X, Kuang T and Yang Y: Non-invasive evaluation of hemodynamics in pulmonary hypertension by a Septal angle measured by computed tomography pulmonary angiography: Comparison with right‑heart catheterization and association with N-terminal pro-B-type natriuretic peptide. Exp Ther Med 6: 1350-1358, 2013.
APA
Tang, Q., Liu, M., Ma, Z., Guo, X., Kuang, T., & Yang, Y. (2013). Non-invasive evaluation of hemodynamics in pulmonary hypertension by a Septal angle measured by computed tomography pulmonary angiography: Comparison with right‑heart catheterization and association with N-terminal pro-B-type natriuretic peptide. Experimental and Therapeutic Medicine, 6, 1350-1358. https://doi.org/10.3892/etm.2013.1324
MLA
Tang, Q., Liu, M., Ma, Z., Guo, X., Kuang, T., Yang, Y."Non-invasive evaluation of hemodynamics in pulmonary hypertension by a Septal angle measured by computed tomography pulmonary angiography: Comparison with right‑heart catheterization and association with N-terminal pro-B-type natriuretic peptide". Experimental and Therapeutic Medicine 6.6 (2013): 1350-1358.
Chicago
Tang, Q., Liu, M., Ma, Z., Guo, X., Kuang, T., Yang, Y."Non-invasive evaluation of hemodynamics in pulmonary hypertension by a Septal angle measured by computed tomography pulmonary angiography: Comparison with right‑heart catheterization and association with N-terminal pro-B-type natriuretic peptide". Experimental and Therapeutic Medicine 6, no. 6 (2013): 1350-1358. https://doi.org/10.3892/etm.2013.1324
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