Successful treatment of relapsed Ménière's disease using selective serotonin reuptake inhibitors: A report of three cases

Goto,Fumiyuki; Tsutsumi,Tomoko; Ogawa,Kaoru

doi:10.3892/etm.2013.1412

2014-February Volume 7 Issue 2

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2014-February Volume 7 Issue 2

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Article

Successful treatment of relapsed Ménière's disease using selective serotonin reuptake inhibitors: A report of three cases

Authors:
- Fumiyuki Goto
- Tomoko Tsutsumi
- Kaoru Ogawa
View Affiliations / Copyright

Affiliations: Department of Otorhinolaryngology, National Hospital Organization, Tokyo Medical Center, Tokyo 152-0021, Japan, Department of Otorhinolaryngology, Hino Municipal Hospital, Tokyo 191-0062, Japan, Department of Otorhinolaryngology, Keio University, Tokyo 160-8520, Japan
Pages: 488-490
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Published online on: November 15, 2013

https://doi.org/10.3892/etm.2013.1412
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Abstract

Patients with Ménière's disease who have relapsed following endolymphatic sac surgery (EDS) or intratympanic gentamicin injection are occasionally treated with intratympanic gentamicin injections or revision surgery. However, there is a potential link between Ménière's disease and anxiety or depression. The use of serotonin selective reuptake inhibitors (SSRIs) is likely be beneficial in the treatment of patients with Ménière's disease. The aim of this report is to describe the benefits of SSRIs in patients with relapsed Meniere's disease. Over the course of two years, three patients were treated for symptoms associated with Ménière's disease with an SSRI (sertraline), with the complete resolution, or significant improvement, of symptoms. In these cases, the SSRI may have treated the associated morbidity and not Ménière's disease itself. Ménière's disease that appears to be resistant to typical otological treatment may not be just Ménière's disease. Ménière's disease may co-exist with three other conditions that are able to cause vestibular symptoms and respond to SSRIs: migraine-associated vertigo (MAV), panic disorders and chronic subjective dizziness (CSD).

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Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

Successful treatment of relapsed Ménière's disease using selective serotonin reuptake inhibitors: A report of three cases

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