Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Oncology Letters
      • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Biomedical Reports
      • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • Information for Authors
    • Information for Reviewers
    • Information for Librarians
    • Information for Advertisers
    • Conferences
  • Language Editing
Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • For Authors
    • For Reviewers
    • For Librarians
    • For Advertisers
    • Conferences
  • Language Editing
Login Register Submit
  • This site uses cookies
  • You can change your cookie settings at any time by following the instructions in our Cookie Policy. To find out more, you may read our Privacy Policy.

    I agree
Search articles by DOI, keyword, author or affiliation
Search
Advanced Search
presentation
Experimental and Therapeutic Medicine
Join Editorial Board Propose a Special Issue
Print ISSN: 1792-0981 Online ISSN: 1792-1015
Journal Cover
April 2013 Volume 5 Issue 4

Full Size Image

Sign up for eToc alerts
Recommend to Library

Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

Journal Cover
April 2013 Volume 5 Issue 4

Full Size Image

Sign up for eToc alerts
Recommend to Library

  • Article
  • Citations
    • Cite This Article
    • Download Citation
    • Create Citation Alert
    • Remove Citation Alert
    • Cited By
  • Similar Articles
    • Related Articles (in Spandidos Publications)
    • Similar Articles (Google Scholar)
    • Similar Articles (PubMed)
  • Download PDF
  • Download XML
  • View XML
Article

Protective effects of Radix Pseudostellariae polysaccharides against exercise‑induced oxidative stress in male rats

  • Authors:
    • Zichao Chen
    • Shanshan Li
    • Xiaoqin Wang
    • Chuan Long Zhang
  • View Affiliations / Copyright

    Affiliations: Department of Physical Education, Sichuan University, Chengdu, Sichuan 610064, P.R. China, Department of Physical Education, Sichuan University, Chengdu, Sichuan 610064, P.R. China, West China Second University Hospital, Sichuan University, Chengdu, Sichuan 610041, P.R. China, Luoyang Institute of Science and Technology, Luoyang, Henan 471023, P.R. China
  • Pages: 1089-1092
    |
    Published online on: January 31, 2013
       https://doi.org/10.3892/etm.2013.942
  • Expand metrics +
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Metrics: Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )
Cited By (CrossRef): 0 citations Loading Articles...

This article is mentioned in:



Abstract

The main purpose of this study was to examine the effect of Radix Pseudostellariae polysaccharides (RPPs) against swimming exercise-induced oxidative stress in male rats. A total of 40 male Wistar rats were randomized into four groups: the control (C), low-dose RPP supplementation (LRS), medium-dose RPP supplementation (MRS) and high‑dose RPP supplementation (HRS) groups. The control group received saline solution and the supplementation groups received different doses of RPPs (100, 200 and 400 mg/kg body weight, respectively). The animals were medicated orally and daily for 28 days. On day 28, the rats were made to swim until exhausted. The exhaustive swimming time and various biochemical parameters, including blood lactate, hemoglobin, catalase (CAT), superoxide dismutase (SOD), glutathione peroxidase (GSH-Px) and malondialdehyde (MDA), were measured. The results showed that RPP supplementation elevates the exercise tolerance and decreases the blood lactate level of rats following exhaustive swimming exercise. RPP supplementation augments the levels of hemoglobin and antioxidant enzymes (CAT, SOD and GSH-Px), and effectively decreases the MDA content of the skeletal muscle of rats, which suggests that RPP supplementation has a protective effect against exercise-induced oxidative stress.
View Figures

Figure 1

Figure 2

Figure 3

Figure 4

View References

1 

Alessio HM: Exercise-induced oxidative stress. Med Sci Sports Exerc. 25:218–224. 1993. View Article : Google Scholar

2 

Bejma J and Ji LL: Aging and acute exercise enhance free radical generation in rat skeletal muscle. J Appl Physiol. 87:465–470. 1999.PubMed/NCBI

3 

Akhtar M, Pillai KK and Vohora D: Effect of thioperamide on modified forced swimming test-induced oxidative stress in mice. Basic Clin Pharmacol Toxicol. 97:218–221. 2005. View Article : Google Scholar : PubMed/NCBI

4 

Pepe H, Balci SS, Revan S, Akalin PP and Kurtoğlu F: Comparison of oxidative stress and antioxidant capacity before and after running exercises in both sexes. Gend Med. 6:587–595. 2009. View Article : Google Scholar : PubMed/NCBI

5 

Banerjee AK, Mandal A, Chanda D and Chakraborti S: Oxidant, antioxidant and physical exercise. Mol Cell Biochem. 253:307–312. 2003. View Article : Google Scholar : PubMed/NCBI

6 

Viña J, Gomez-Cabrera MC, Lloret A, Marquez R, Miñana JB, Pallardó FV and Sastre J: Free radicals in exhaustive physical exercise: mechanism of production, and protection by anti-oxidants. IUBMB Life. 50:271–277. 2000.PubMed/NCBI

7 

Taysi S, Oztasan N, Efe H, Polat MF, Gumustekin K, Siktar E, Canakci E, Akcay F, Dane S and Gul M: Endurance training attenuates the oxidative stress due to acute exhaustive exercise in rat liver. Acta Physiol Hung. 95:337–347. 2008. View Article : Google Scholar : PubMed/NCBI

8 

Powers SK, DeRuisseau KC, Quindry J and Hamilton KL: Dietary antioxidants and exercise. J Sports Sci. 22:81–94. 2004. View Article : Google Scholar : PubMed/NCBI

9 

Gong Z, Dai Y, Ma H, Wang Z and Yu G: The effect of Radix Pseudostellariae from 8 habitats on spleen-deficiency and immunologic function. Zhong Yao Cai. 24:281–282. 2001.(In Chinese).

10 

Lin H, Chen Q, Zhao J and Zhou P: Determination of free amino acid content in Radix Pseudostellariae using near infrared (NIR) spectroscopy and different multivariate calibrations. J Pharm Biomed Anal. 50:803–808. 2009. View Article : Google Scholar : PubMed/NCBI

11 

Wong CK, Leung KN, Fung KP and Choy YM: The immunostimulating activities of anti-tumor polysaccharides from Pseudostellaria heterophylla. Immunopharmacology. 28:47–54. 1994. View Article : Google Scholar : PubMed/NCBI

12 

Ng TB, Liu F and Wang HX: The antioxidant effects of aqueous and organic extracts of Panax quinquefolium, Panax notoginseng, Codonopsis pilosula, Pseudostellaria heterophylla and Glehnia littoralis. J Ethnopharmacol. 93:285–288. 2004.PubMed/NCBI

13 

Cai J, Li X, Chen X, et al: The immune effects of crude extract of Pseudostellaria polysaccharide in mice. Journal of Fujian College of Traditional Chinese Medicine. 15:33–35. 2005.(In Chinese).

14 

Li J and Fu Y: Effect of IgY, Coptis chinensis and Radix Pseudostellariae on gastric mucous membrane in mice with Helicobacter pylori infection. Chinese Journal of Clinical Rehabilitation. 10:78–80. 2006.(In Chinese).

15 

Wang WK: Recent advances in studies on Pseudostellariae Radix. Chinese Journal of Experimental Traditional Medical Formulae. 17:264–267. 2011.(In Chinese).

16 

(NRC) Institute of Laboratory Animal Resources, Commission on Life Sciences, National Research Council: Guide for the Care and Use of Laboratory Animals. National Academies Press; Washington, DC: pp. 11–45. 1996

17 

Chen YY, Ding Y, Wang W, Wang RF, Su H and Du LJ: Determination of polysaccharide in Radix pseudostellariae extract by size-exclusion high-performance liquid chromatography. Tsinghua Sci Tech. 12:389–393. 2007.

18 

Sheng R, Xu X, Tang Q, Bian D, Li Y, Qian C, He X, Gao X, Pan R, Wang C, Luo Y, Xia Y and Dai Y: Polysaccharide of Radix Pseudostellariae improves chronic fatigue syndrome induced by poly I:C in mice. Evid Based Complement Alternat Med. 2011:8405162011. View Article : Google Scholar : PubMed/NCBI

19 

Lee SP, Mar GY and Ng LT: Effects of tocotrienol-rich fraction on exercise endurance capacity and oxidative stress in forced swimming rats. Eur J Appl Physiol. 107:587–595. 2009. View Article : Google Scholar : PubMed/NCBI

20 

Misra DS, Maiti R and Ghosh D: Protection of swimming-induced oxidative stress in some vital organs by the treatment of composite extract of Withania somnifera, Ocimum sanctum and Zingiber officinalis in male rat. Afr J Tradit Complement Altern Med. 6:534–543. 2009.PubMed/NCBI

21 

Ou PF and Zhang L: Stimulatory effects of soybean isoflavones on exercise performance. Int J Phys Sci. 5:2272–2277. 2010.

22 

Wei W, Zheng LY, Yu MY, Jiang N, Yang ZR and Luo X: Anti-fatigue activity of extract form the submerged fermentation of Ganoderma Lucidum using Radix astragali as substrate. J Anim Plant Sci. 6:677–684. 2010.

23 

Ikeuchi M, Yamaguchi K, Koyama T, Sono Y and Yazawa K: Effects of fenugreek seeds (Trigonella foenum greaecum) extract on endurance capacity in mice. J Nutr Sci Vitaminol (Tokyo). 52:287–292. 2006.

24 

Kato J, Ruram AA, Singh SS, Devi SB, Devi TI and Singh WG: Lipid peroxidation and antioxidant vitamins in urolithiasis. Indian J Clin Biochem. 22:128–130. 2007. View Article : Google Scholar : PubMed/NCBI

25 

Li F, Tang H, Xiao F, Gong J, Peng Y and Meng X: Protective effect of salidroside from Rhodiolae Radix on diabetes-induced oxidative stress in mice. Molecules. 16:9912–9924. 2011. View Article : Google Scholar : PubMed/NCBI

26 

Kanter MM, Nolte LA and Holloszy JO: Effects of an antioxidant vitamin mixture on lipid peroxidation at rest and postexercise. J Appl Physiol. 74:965–969. 1993.PubMed/NCBI

27 

Zhang M, Izumi I, Kagamimori S, Sokejima S, Yamagami T, Liu Z and Qi B: Role of taurine supplementation to prevent exercise-induced oxidative stress in healthy young men. Amino Acids. 26:203–207. 2004. View Article : Google Scholar : PubMed/NCBI

28 

Huang CC, Lin TJ, Lu YF, Chen CC, Huang CY and Lin WT: Protective effects of L-arginine supplementation against exhaustive exercise-induced oxidative stress in young rat tissues. Chin J Physiol. 52:306–315. 2009. View Article : Google Scholar

29 

Cotgreave IA, Moldéus P and Orrenius S: Host biochemical defense mechanisms against prooxidants. Annu Rev Pharmacol Toxicol. 28:189–212. 1988. View Article : Google Scholar : PubMed/NCBI

Related Articles

  • Abstract
  • View
  • Download
  • Twitter
Copy and paste a formatted citation
Spandidos Publications style
Chen Z, Li S, Wang X and Zhang CL: Protective effects of Radix Pseudostellariae polysaccharides against exercise‑induced oxidative stress in male rats. Exp Ther Med 5: 1089-1092, 2013.
APA
Chen, Z., Li, S., Wang, X., & Zhang, C.L. (2013). Protective effects of Radix Pseudostellariae polysaccharides against exercise‑induced oxidative stress in male rats. Experimental and Therapeutic Medicine, 5, 1089-1092. https://doi.org/10.3892/etm.2013.942
MLA
Chen, Z., Li, S., Wang, X., Zhang, C. L."Protective effects of Radix Pseudostellariae polysaccharides against exercise‑induced oxidative stress in male rats". Experimental and Therapeutic Medicine 5.4 (2013): 1089-1092.
Chicago
Chen, Z., Li, S., Wang, X., Zhang, C. L."Protective effects of Radix Pseudostellariae polysaccharides against exercise‑induced oxidative stress in male rats". Experimental and Therapeutic Medicine 5, no. 4 (2013): 1089-1092. https://doi.org/10.3892/etm.2013.942
Copy and paste a formatted citation
x
Spandidos Publications style
Chen Z, Li S, Wang X and Zhang CL: Protective effects of Radix Pseudostellariae polysaccharides against exercise‑induced oxidative stress in male rats. Exp Ther Med 5: 1089-1092, 2013.
APA
Chen, Z., Li, S., Wang, X., & Zhang, C.L. (2013). Protective effects of Radix Pseudostellariae polysaccharides against exercise‑induced oxidative stress in male rats. Experimental and Therapeutic Medicine, 5, 1089-1092. https://doi.org/10.3892/etm.2013.942
MLA
Chen, Z., Li, S., Wang, X., Zhang, C. L."Protective effects of Radix Pseudostellariae polysaccharides against exercise‑induced oxidative stress in male rats". Experimental and Therapeutic Medicine 5.4 (2013): 1089-1092.
Chicago
Chen, Z., Li, S., Wang, X., Zhang, C. L."Protective effects of Radix Pseudostellariae polysaccharides against exercise‑induced oxidative stress in male rats". Experimental and Therapeutic Medicine 5, no. 4 (2013): 1089-1092. https://doi.org/10.3892/etm.2013.942
Follow us
  • Twitter
  • LinkedIn
  • Facebook
About
  • Spandidos Publications
  • Careers
  • Cookie Policy
  • Privacy Policy
How can we help?
  • Help
  • Live Chat
  • Contact
  • Email to our Support Team