Diagnosis and treatment of SAPHO syndrome: A case report

Song,Xinghua; Sun,Wenwen; Meng,Zhaowei; Gong,Lu; Tan,Jian; Jia,Qiang; Yu,Chunshui; Yu,Tielian

doi:10.3892/etm.2014.1758

August-2014 Volume 8 Issue 2

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August-2014 Volume 8 Issue 2

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Case Report

Diagnosis and treatment of SAPHO syndrome: A case report

Authors:
- Xinghua Song
- Wenwen Sun
- Zhaowei Meng
- Lu Gong
- Jian Tan
- Qiang Jia
- Chunshui Yu
- Tielian Yu
View Affiliations / Copyright

Affiliations: Department of Nuclear Medicine, Tianjin Medical University General Hospital, Tianjin 300052, P.R.China, Department of Rheumatology and Immunological Diseases, Tianjin Medical University General Hospital, Tianjin 300052, P.R.China, Department of Radiology, Tianjin Medical University General Hospital, Tianjin 300052, P.R.China
Pages: 419-422
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Published online on: June 4, 2014

https://doi.org/10.3892/etm.2014.1758
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Abstract

The present study reports a rare case of synovitis, acne, pustulosis, hyperostosis and osteitis (SAPHO) syndrome in an adult male. The 42‑year‑old man complained of skin lesions, chest pain and lumbago. Laboratory evaluations demonstrated an elevated erythrocyte sedimentation rate and increased levels of C‑reactive protein. Computerized tomography, bone scintigraphy and magnetic resonance imaging revealed multiple bone lesions. A diagnosis of SAPHO syndrome was made. Non‑steroidal anti‑inflammatory drugs, alendronate sodium and steroids were administered, which resulted in clinical improvement. The current case study demonstrates that skin manifestation and multiple imaging modalities are important in generating a definite diagnosis of SAPHO syndrome, and that early treatment is vital for a positive outcome.

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Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

Diagnosis and treatment of SAPHO syndrome: A case report

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