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Article

Association between cardiothoracic ratio, left ventricular size and systolic function in patients undergoing computed tomography coronary angiography

  • Authors:
    • Yinsu Zhu
    • Hai Xu
    • Xiaomei Zhu
    • Yongyue Wei
    • Guanyu Yang
    • Yi Xu
    • Lijun Tang
  • View Affiliations / Copyright

    Affiliations: Department of Radiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu 210029, P.R. China, Department of Biostatistics, School of Public Health, Nanjing Medical University, Nanjing, Jiangsu 210029, P.R. China, Laboratory of Image Science and Technology, School of Computer Science and Engineering, Southeast University, Nanjing, Jiangsu 210096, P.R. China
  • Pages: 1757-1763
    |
    Published online on: October 13, 2014
       https://doi.org/10.3892/etm.2014.2016
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Abstract

The present study aimed to investigate the association between cardiothoracic ratio (CTR) and left ventricular (LV) systolic function parameters in patients with or without preserved LV ejection fraction (LVEF). A total of 203 subjects suspected with coronary artery disease underwent chest radiography and dual source computed tomography coronary angiography (DSCT‑CA). The LV systolic function parameters: LV end‑diastolic volume index (LVEDVI), LV end‑systolic volume index (LVESVI), and LVEF were measured from the DSCT‑CA. The association between CTR and LV systolic function parameters was analyzed according to LVEF value (<55%, depressed LVEF group; versus ≥55%, preserved LVEF group) and CTR value (<0.5, normal range CTR group; versus ≥0.5, larger CTR group). The LVEDVI and LVESVI were higher in the depressed LVEF group compared with the preserved LVEF group (108.56±57.15 vs. 67.52±14.56 ml/m2, P<0.001; and 64.07±37.81 vs. 20.23±7.23 ml/m2, P<0.001, respectively) and lower in the normal range CTR group compared with the larger CTR group (67.10±15.00 vs. 77.30±34.32 ml/m2, P=0.009 and 21.94±8.96 vs. 28.97±26.54 ml/m2, P=0.017, respectively). Significant correlations were found between CTR and LVEDVI, and LVESVI and LVEF in the depressed LVEF group (r=0.66, P<0.001; r=0.65, P<0.001; and r=‑0.46, P=0.018, respectively). However, there was no significant association detected between CTR and LV systolic function parameters in the other subgroups. The LVEDVI and LVESVI showed an inverse correlation with the LVEF in each group. Although the CTR was not a reliable indicator of LV size and systolic function in patients with preserved LVEF, it was correlated with LV size and LVEF in patients with depressed LVEF.
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Copy and paste a formatted citation
Spandidos Publications style
Zhu Y, Xu H, Zhu X, Wei Y, Yang G, Xu Y and Tang L: Association between cardiothoracic ratio, left ventricular size and systolic function in patients undergoing computed tomography coronary angiography. Exp Ther Med 8: 1757-1763, 2014.
APA
Zhu, Y., Xu, H., Zhu, X., Wei, Y., Yang, G., Xu, Y., & Tang, L. (2014). Association between cardiothoracic ratio, left ventricular size and systolic function in patients undergoing computed tomography coronary angiography. Experimental and Therapeutic Medicine, 8, 1757-1763. https://doi.org/10.3892/etm.2014.2016
MLA
Zhu, Y., Xu, H., Zhu, X., Wei, Y., Yang, G., Xu, Y., Tang, L."Association between cardiothoracic ratio, left ventricular size and systolic function in patients undergoing computed tomography coronary angiography". Experimental and Therapeutic Medicine 8.6 (2014): 1757-1763.
Chicago
Zhu, Y., Xu, H., Zhu, X., Wei, Y., Yang, G., Xu, Y., Tang, L."Association between cardiothoracic ratio, left ventricular size and systolic function in patients undergoing computed tomography coronary angiography". Experimental and Therapeutic Medicine 8, no. 6 (2014): 1757-1763. https://doi.org/10.3892/etm.2014.2016
Copy and paste a formatted citation
x
Spandidos Publications style
Zhu Y, Xu H, Zhu X, Wei Y, Yang G, Xu Y and Tang L: Association between cardiothoracic ratio, left ventricular size and systolic function in patients undergoing computed tomography coronary angiography. Exp Ther Med 8: 1757-1763, 2014.
APA
Zhu, Y., Xu, H., Zhu, X., Wei, Y., Yang, G., Xu, Y., & Tang, L. (2014). Association between cardiothoracic ratio, left ventricular size and systolic function in patients undergoing computed tomography coronary angiography. Experimental and Therapeutic Medicine, 8, 1757-1763. https://doi.org/10.3892/etm.2014.2016
MLA
Zhu, Y., Xu, H., Zhu, X., Wei, Y., Yang, G., Xu, Y., Tang, L."Association between cardiothoracic ratio, left ventricular size and systolic function in patients undergoing computed tomography coronary angiography". Experimental and Therapeutic Medicine 8.6 (2014): 1757-1763.
Chicago
Zhu, Y., Xu, H., Zhu, X., Wei, Y., Yang, G., Xu, Y., Tang, L."Association between cardiothoracic ratio, left ventricular size and systolic function in patients undergoing computed tomography coronary angiography". Experimental and Therapeutic Medicine 8, no. 6 (2014): 1757-1763. https://doi.org/10.3892/etm.2014.2016
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